期刊
JOURNAL OF CLINICAL MEDICINE
卷 10, 期 22, 页码 -出版社
MDPI
DOI: 10.3390/jcm10225263
关键词
peritoneal carcinomatosis; peritoneal metastases; gastric cancer; cytoreductive surgery; surgical technique; peritonectomy
资金
- NIH/NCI Cancer Center [P30 CA008748]
Peritoneal carcinomatosis of gastric origin is still considered a terminal disease with poor outcomes due to limited treatment options. However, recent evidence suggests that cytoreductive surgery may improve survival in selected patients with gastric cancer. These procedures are complex and require high surgical expertise to prevent postoperative complications.
Due to limited systemic treatment options, peritoneal carcinomatosis of gastric origin is still associated with a dismal outcome and is claimed a terminal disease. In the past, surgery had not been considered as a potential treatment option. However, there is emerging evidence that in selected patients, locoregional treatment modalities including cytoreductive surgery of peritoneal carcinomatosis can improve survival in patients with gastric cancer. These operative procedures are complex and challenging, and a high surgical expertise of the treating physician is necessary to prevent major postoperative morbidity and mortality with a delay of further systemic therapy. This review summarizes our current knowledge and personal experience regarding the techniques of cytoreductive surgery for peritoneal metastasis of gastric origin.
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