4.7 Review

Simple Serum Pancreatic Ductal Adenocarcinoma (PDAC) Protein Biomarkers-Is There Anything in Sight?

期刊

JOURNAL OF CLINICAL MEDICINE
卷 10, 期 22, 页码 -

出版社

MDPI
DOI: 10.3390/jcm10225463

关键词

PDAC biomarkers; early diagnostic; ELISA

资金

  1. Department of Digestive Tract Diseases, Medical University of Lodz [503/1-002-01/503-11-001-19-00]

向作者/读者索取更多资源

The poor prognosis of PDAC is attributed to a lack of effective treatment and late diagnosis, while early detection could significantly decrease mortality. Ideal biomarkers for PDAC should be cost-effective, detectable in easily accessible biological material, and present in sufficient concentration in the earliest possible phase of the disease.
A poor PDAC prognosis is due to a lack of effective treatment and late diagnosis. The early detection of PDAC could significantly decrease mortality and save lives. Idealbiomarkers for PDAC should be cost-effective, detectable in easily accessible biological material, and present in sufficient concentration in the earliest possible phase of the disease. This review addresses newly selected, simple protein biomarkers-new ones such as thrombospondin-2, insulin-linked binding protein 2, lysophosphatidic acid, and autotaxin and conventional ones such as Ca19-9, inflammatory factors, and coagulation factors. Their possible use in the early detection of PDAC, differentiation from benign diseases, prognosis, and treatment response prediction is discussed. We also address the usefulness of possible combinations of biomarkers in diagnostic panels.

作者

我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。

评论

主要评分

4.7
评分不足

次要评分

新颖性
-
重要性
-
科学严谨性
-
评价这篇论文

推荐

暂无数据
暂无数据