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Fusarium Keratitis-Review of Current Treatment Possibilities

期刊

JOURNAL OF CLINICAL MEDICINE
卷 10, 期 23, 页码 -

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MDPI
DOI: 10.3390/jcm10235468

关键词

Fusarium keratitis; Fusarium keratitis treatment; natamycin; voriconazole; amphotericin B

资金

  1. Wroclaw Medical University Subvention for the Department of Ophthalmology [SUB.C240.21.036]

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The management of Fusarium keratitis is challenging due to delays in the onset of symptoms from an injury and difficulties in differentiating fungal from bacterial infections. Therapeutic options are limited, including antifungals, antiseptics, and surgical interventions.
In many parts of the world, fungi are the predominant cause of infectious keratitis; among which, Fusarium is the most commonly isolated pathogen. The clinical management of this ophthalmic emergency is challenging. Due to the retardation of the first symptoms from an injury and the inability to differentiate fungal from bacterial infections based on clinical symptoms and difficult microbial diagnostics, proper treatment, in many cases, is postponed. Moreover, therapeutical options of Fusarium keratitis remain limited. This paper summarizes the available treatment modalities of Fusarium keratitis, including antifungals and their routes of administration, antiseptics, and surgical interventions.

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