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FREE RADICAL BIOLOGY AND MEDICINE (2012)
Epidemiology of Viral Hepatitis and Hepatocellular Carcinoma
Hashem B. El-Serag
GASTROENTEROLOGY (2012)
An international, multicenter phase II trial of bortezomib in patients with hepatocellular carcinoma
George P. Kim et al.
INVESTIGATIONAL NEW DRUGS (2012)
Design, Synthesis, and Pharmacological Evaluation of Bis-2-(5-phenylacetamido-1,2,4-thiadiazol-2-yl)ethyl Sulfide 3 (BPTES) Analogs as Glutaminase Inhibitors
Krupa Shukla et al.
JOURNAL OF MEDICINAL CHEMISTRY (2012)
Fatty acid-binding protein 5 promotes cell proliferation and invasion in human intrahepatic cholangiocarcinoma
Chi-Young Jeong et al.
ONCOLOGY REPORTS (2012)
Increased expression of CYP4Z1 promotes tumor angiogenesis and growth in human breast cancer
Wei Yu et al.
TOXICOLOGY AND APPLIED PHARMACOLOGY (2012)
Pyruvate Kinase M2 Is a PHD3-Stimulated Coactivator for Hypoxia-Inducible Factor 1
Weibo Luo et al.
CELL (2011)
The Lipogenesis Pathway as a Cancer Target
Hanley N. Abramson
JOURNAL OF MEDICINAL CHEMISTRY (2011)
p53 regulates biosynthesis through direct inactivation of glucose-6-phosphate dehydrogenase
Peng Jiang et al.
NATURE CELL BIOLOGY (2011)
Fatty acid synthase as a potential therapeutic target in cancer
Richard Flavin et al.
FUTURE ONCOLOGY (2010)
Doxorubicin Plus Sorafenib vs Doxorubicin Alone in Patients With Advanced Hepatocellular Carcinoma A Randomized Trial
Ghassan K. Abou-Alfa et al.
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2010)
Genetic, structural and biochemical basis of carbamoyl phosphate synthetase 1 deficiency
Ana Isabel Martinez et al.
MOLECULAR GENETICS AND METABOLISM (2010)
Phosphate-activated glutaminase (GLS2), a p53-inducible regulator of glutamine metabolism and reactive oxygen species
Sawako Suzuki et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
GLUT1 Expression Is Increased in Hepatocellular Carcinoma and Promotes Tumorigenesis
Thomas Amann et al.
AMERICAN JOURNAL OF PATHOLOGY (2009)
Inhibition of energy-producing pathways of HepG2 cells by 3-bromopyruvate
Ana Paula Pereira da Silva et al.
BIOCHEMICAL JOURNAL (2009)
Novel roles for GAPDH in cell death and carcinogenesis
A. Colell et al.
CELL DEATH AND DIFFERENTIATION (2009)
The molecular determinants of de novo nucleotide biosynthesis in cancer cells
Xuemei Tong et al.
CURRENT OPINION IN GENETICS & DEVELOPMENT (2009)
Understanding the Warburg Effect: The Metabolic Requirements of Cell Proliferation
Matthew G. Vander Heiden et al.
SCIENCE (2009)
Cytochrome P450 omega hydroxylase (CYP4) function in fatty acid metabolism and metabolic diseases
James P. Hardwick
BIOCHEMICAL PHARMACOLOGY (2008)
Mitochondrial cholesterol contributes to chemotherapy resistance in hepatocellular carcinoma
Joan Montero et al.
CANCER RESEARCH (2008)
Chemoembolization Combined with Pravastatin Improves Survival in Patients with Hepatocellular Carcinoma
Hannah Graf et al.
DIGESTION (2008)
A new mechanism of drug resistance in breast cancer cells: fatty acid synthase overexpression-mediated palmitate overproduction
Hailan Liu et al.
MOLECULAR CANCER THERAPEUTICS (2008)
Sorafenib in advanced hepatocellular carcinoma
Josep M. Llovet et al.
NEW ENGLAND JOURNAL OF MEDICINE (2008)
Metformin inhibits mammalian target of rapamycin-dependent translation initiation in breast cancer cells
Ryan J. O. Dowling et al.
CANCER RESEARCH (2007)
trans-2-phenylcyclopropylamine is a mechanism-based inactivator of the histone demethylase LSD1
Dawn M. Z. Schmidt et al.
BIOCHEMISTRY (2007)
Expression of transketolase TKTL1 predicts colon and urothelial cancer patient survival: Warburg effect reinterpreted
S Langbein et al.
BRITISH JOURNAL OF CANCER (2006)
ATP citrate lyase inhibition can suppress tumor cell growth
G Hatzivassiliou et al.
CANCER CELL (2005)
Antitumoral actions of the anti-obesity drug orlistat (Xenical™) in breast cancer cells:: blockade of cell cycle progression, promotion of apoptotic cell death and PEA3-mediated transcriptional repression of Her2/neu (erbB-2) oncogene
JA Menendez et al.
ANNALS OF ONCOLOGY (2005)
Pyruvate kinase type M2 and its role in tumor growth and spreading
S Mazurek et al.
SEMINARS IN CANCER BIOLOGY (2005)
Selection of DNA aptamers against rat liver X receptors
I Surugiu-Wärnmark et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2005)
Identification of a novel mammary-restricted cytochrome P450, CYP4Z1, with overexpression in breast carcinoma
MA Rieger et al.
CANCER RESEARCH (2004)
The tumor suppressor LKB1 kinase directly activates AMP-activated kinase and regulates apoptosis in response to energy stress
RJ Shaw et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
Glutamine availability up-regulates expression of the amino acid transporter protein ASCT2 in HepG2 cells and stimulates the ASCT2 promoter
CI Bungard et al.
BIOCHEMICAL JOURNAL (2004)
HIf1 and oxygen sensing in the brain
FR Sharp et al.
NATURE REVIEWS NEUROSCIENCE (2004)
Alcohol and hepatocellular carcinoma
TR Morgan et al.
GASTROENTEROLOGY (2004)
Recent insights into stearoyl-CoA desaturase-1
JM Ntambi et al.
CURRENT OPINION IN LIPIDOLOGY (2003)
Lipoprotein lipase: structure, function, regulation, and role in disease
JR Mead et al.
JOURNAL OF MOLECULAR MEDICINE-JMM (2002)
The key role of anaplerosis and cataplerosis for citric acid cycle function
OE Owen et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
C75 increases peripheral energy utilization and fatty acid oxidation in diet-induced obesity
JN Thupari et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)
Expression of l-type amino acid transporter 1 (LAT1) and 4F2 heavy chain (4F2hc) in liver tumor lesions of rat models
H Ohkame et al.
JOURNAL OF SURGICAL ONCOLOGY (2001)