4.6 Review

Multiple roles of ribosomal antimicrobial peptides in tackling global antimicrobial resistance

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Letter Gastroenterology & Hepatology

Global prediction of primary liver cancer incidences and mortality in 2040

Chenxi Li et al.

JOURNAL OF HEPATOLOGY (2023)

Article Biochemistry & Molecular Biology

DRAMP 3.0: an enhanced comprehensive data repository of antimicrobial peptides

Guobang Shi et al.

Summary: The new version of the antimicrobial peptide database (DRAMP) focuses on the development of stapled antimicrobial peptides and includes a subclass for storing information on these special chemically modified AMPs. It also adds cytotoxicity property of AMPs and expands newly discovered AMP data, with a total of 22259 entries and links to experimentally determined structures in the Protein Data Bank.

NUCLEIC ACIDS RESEARCH (2022)

Review Biotechnology & Applied Microbiology

Strategies for antimicrobial peptide coatings on medical devices: a review and regulatory science perspective

Mehdi Kazemzadeh-Narbat et al.

Summary: This review discusses the use of antimicrobial peptides (AMPs) as an alternative to conventional antibiotics to reduce infections in medical devices, focusing on their broad-spectrum antimicrobial activity and strategies for incorporating them into medical devices materials. The regulatory perspective on AMP coatings, specifically in the US market, aims to bridge the gap between academic studies and preclinical testing to advance the regulatory science of antimicrobial coatings.

CRITICAL REVIEWS IN BIOTECHNOLOGY (2021)

Article Infectious Diseases

WHO 2020 report on the antibacterial production and development pipeline

Priya Venkatesan

Lancet Microbe (2021)

Review Chemistry, Multidisciplinary

De Novo Design of Flavonoid-Based Mimetics of Cationic Antimicrobial Peptides: Discovery, Development, and Applications

Shuimu Lin et al.

Summary: The rapid development of pathogen resistance to traditional antibiotics poses a major challenge to public health. Plant-derived flavonoids, such as xanthones and flavones, are active components with significant pharmacological actions. By designing and synthesizing flavonoid-based mimics, it may be possible to overcome the limitations associated with CAMPs and develop new therapeutic antimicrobial agents.

ACCOUNTS OF CHEMICAL RESEARCH (2021)

Article Biochemistry & Molecular Biology

Development of Antimicrobial Stapled Peptides Based on Magainin 2 Sequence

Motoharu Hirano et al.

Summary: Magainin 2, an antimicrobial peptide, relies on 17 amino acid residues for its antimicrobial activity, and derivatives with hydrocarbon stapling side chains can enhance this activity by stabilizing helical structures. The study found that hydrocarbon stapling significantly stabilizes helical structures of peptides, leading to improved antimicrobial activity without significant hemolytic effects. These findings suggest potential for developing novel antimicrobial agents based on Magainin 2 derivatives.

MOLECULES (2021)

Article Chemistry, Physical

Protonectin peptides target lipids, act at the interface and selectively kill metastatic breast cancer cells while preserving morphological integrity

Danubia Batista Martins et al.

Summary: This study investigated the natural peptide protonectin (PTN) and its N-terminal fragment (PTN1-6) on the activity mechanism against cancer cells. The results showed that the aggregation of PTN/PTN1-6 in model membranes reduced, but it had a selective interaction on breast cancer cells and epithelial cells.

JOURNAL OF COLLOID AND INTERFACE SCIENCE (2021)

Article Fisheries

Identification and characterization of novel bi-functional cathelicidins from the black-spotted frog (Pelophylax nigromaculata) with both anti-infective and antioxidant activities

Yan Wang et al.

Summary: The novel antimicrobial peptides PN-CATH1 and 2 discovered from Pelophylax nigromaculata exhibit moderate, but broad-spectrum and rapid antimicrobial activities by inducing bacterial membrane disruption and possibly generating intracellular ROS formation. They also possess potent anti-biofilm and persister cell killing activity, as well as anti-inflammatory and antioxidant activities, making them potential candidates for the development of new antimicrobial and antioxidant drugs.

DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY (2021)

Article Biochemistry & Molecular Biology

The effect of acidic pH on the adsorption and lytic activity of the peptides Polybia-MP1 and its histidine-containing analog in anionic lipid membrane: a biophysical study by molecular dynamics and spectroscopy

Ingrid Bernardes Santana Martins et al.

Summary: Antimicrobial peptides are short sequences rich in charged and non-polar residues that act on the lipid phase of cell membranes. Polybia-MP1, a broad-spectrum bactericide from native wasps, and its analog H-MP1 showed sensitivity to bulk pH in terms of their adsorption, insertion, and lytic activity to model membranes. Molecular dynamics simulations provided atomistic details of the peptides' interactions with lipid bilayers, highlighting the importance of pH in modulating their efficiency.

AMINO ACIDS (2021)

Article Biochemistry & Molecular Biology

C-terminus amidation influences biological activity and membrane interaction of maculatin 1.1

Shiying Zhu et al.

Summary: Cationic antimicrobial peptides can combat infections by targeting the cell membrane of microbes, with C-terminus amidation enhancing stability and antibacterial ability, while also increasing membrane disruptive ability.

AMINO ACIDS (2021)

Review Biochemistry & Molecular Biology

Chemical approaches in the development of natural nontoxic peptide Polybia-MP1 as a potential dual antimicrobial and antitumor agent

Huy L. Xuan et al.

Summary: Polybia-MP1 is a natural antimicrobial peptide with therapeutic potential, showing potent antibacterial, antifungal, and anticancer properties, with relatively low hemolytic activity compared to other similar peptides. Efforts have been made to develop this peptide into a more druggable form.

AMINO ACIDS (2021)

Article Multidisciplinary Sciences

Identification of potential therapeutic antimicrobial peptides against Acinetobacter baumannii in a mouse model of pneumonia

Chiau-Jing Jung et al.

Summary: Antimicrobial peptides (AMP) are considered an ideal strategy for treating Acinetobacter baumannii-induced pneumonia due to their broad-spectrum antimicrobial activity and low bacterial resistance rates. In a mouse model, two AMPs (SMAP-29 and TP4) showed prophylactic effects, while derivatives of TP4 (dN4 and dC4) exhibited therapeutic activity in inhibiting and eliminating A. baumannii biofilms.

SCIENTIFIC REPORTS (2021)

Article Biochemistry & Molecular Biology

Cutaneous antimicrobial peptides: New ?actors? in pollution related inflammatory conditions

Brittany Woodby et al.

Summary: Exposure to O3 is reported to affect AMP levels in the skin, playing a role in skin inflammatory conditions, indicating a possible defensive strategy against pollution-associated skin conditions.

REDOX BIOLOGY (2021)

Review Pharmacology & Pharmacy

Antimicrobial peptides towards clinical application: Delivery and formulation

Cheng Wang et al.

Summary: This article reviews recent studies on the delivery and formulation of antimicrobial peptides, categorizing strategies driven by physical interactions or chemical conjugation reactions, and covering carriers from inorganic solid nanoparticles to organic micelles, liposomes, and hydrogels. Targeted delivery, responsive release, and strategies to increase oral bioavailability of antimicrobial peptides are discussed, highlighting the recent progress towards clinical application.

ADVANCED DRUG DELIVERY REVIEWS (2021)

Article Biochemistry & Molecular Biology

Comparative Antimicrobial Activity of Hp404 Peptide and Its Analogs against Acinetobacter baumannii

Min Ji Hong et al.

Summary: The analog peptides derived from Hp1404 exhibit antimicrobial activity against multidrug-resistant Acinetobacter baumannii with lower cytotoxicity. They effectively permeate bacterial membranes and inhibit biofilm formation, showing potential as therapeutic agents for A. baumannii infection.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2021)

Article Chemistry, Medicinal

Amphipathic Barbiturates as Mimics of Antimicrobial Peptides and the Marine Natural Products Eusynstyelamides with Activity against Multi-resistant Clinical Isolates

Marianne H. Paulsen et al.

Summary: This study presents a series of synthetic cationic amphipathic barbiturates with potent antimicrobial activity against multi-resistant bacteria. Inspired by the pharmacophore model of small antimicrobial peptides and marine antimicrobials, these compounds show promising in vivo antibiotic efficacy and strong membrane disruptive effects. The results suggest that the design strategy based on small AMPs and marine compounds can lead to the development of highly effective peptidomimetics against multi-drug resistant bacteria.

JOURNAL OF MEDICINAL CHEMISTRY (2021)

Article Chemistry, Medicinal

First-in-Class Cyclic Temporin L Analogue: Design, Synthesis, and Antimicrobial Assessment

Rosa Bellavita et al.

Summary: This study aimed to increase the alpha-helicity content of temporin L by introducing diverse side-chain tethering strategies, leading to the development of novel cyclic analogues. The results showed that these cyclic analogues exhibited potential antimicrobial and cytotoxic activities, paving the way for the development of improved antibiotic cyclic AMP analogues.

JOURNAL OF MEDICINAL CHEMISTRY (2021)

Review Chemistry, Multidisciplinary

Design, optimization, and nanotechnology of antimicrobial peptides: From exploration to applications

Peng Tan et al.

Summary: The abuse of antibiotics causing antibiotic resistance is a serious threat to human health, and antimicrobial peptides have become potential antibiotic alternatives due to their unique mechanisms. Despite the problems with natural AMPs, advancements in molecular design, optimization strategies, and nanotechnology have shown potential to improve their properties. Progress in the design and optimization strategies of AMPs lay a theoretical foundation for the development of peptide-based antimicrobial nanomaterials, providing more effective antibiotic alternatives.

NANO TODAY (2021)

Review Agriculture, Dairy & Animal Science

Antimicrobial peptides as a feed additive alternative to animal production, food safety and public health implications: An overview

Raiza F. Silveira et al.

Summary: Feed additives have been beneficial in animal nutrition, but the use of antibiotics has led to antimicrobial resistance. Antimicrobial peptides are a promising alternative to prevent the development of resistant microorganisms and improve feed efficiency in animal nutrition.

ANIMAL NUTRITION (2021)

Review Chemistry, Multidisciplinary

Chemically modified and conjugated antimicrobial peptides against superbugs

Wenyi Li et al.

Summary: Antimicrobial resistance is a major threat to human health, and new antimicrobial peptides are emerging as a promising alternative with potent activity against a wide range of bacteria and low risk of inducing resistance. Chemical modifications can further enhance antimicrobial activity, leading to more effective solutions for biomedical challenges.

CHEMICAL SOCIETY REVIEWS (2021)

Article Biochemistry & Molecular Biology

Production of a Recombinant Peptide (Lasioglossin LL ΙΙΙ) and Assessment of Antibacterial and Antioxidant Activity

Abbas Tanhaeian et al.

INTERNATIONAL JOURNAL OF PEPTIDE RESEARCH AND THERAPEUTICS (2020)

Article Biochemistry & Molecular Biology

De Novo Hydrocarbon-Stapling Design of Single-Turn α-Helical Antimicrobial Peptides

Zhixia Chen et al.

INTERNATIONAL JOURNAL OF PEPTIDE RESEARCH AND THERAPEUTICS (2020)

Review Biotechnology & Applied Microbiology

Plantaricin bacteriocins: As safe alternative antimicrobial peptides in food preservation-A review

Raghda Abdulhussain Kareem et al.

JOURNAL OF FOOD SAFETY (2020)

Review Biotechnology & Applied Microbiology

Antimicrobial host defence peptides: functions and clinical potential

Neeloffer Mookherjee et al.

NATURE REVIEWS DRUG DISCOVERY (2020)

Review Chemistry, Multidisciplinary

Formulation technologies and advances for oral delivery of novel nitroimidazoles and antimicrobial peptides

John Ndayishimiye et al.

JOURNAL OF CONTROLLED RELEASE (2020)

Review Multidisciplinary Sciences

Antimicrobial peptides: Application informed by evolution

Brian P. Lazzaro et al.

SCIENCE (2020)

Article Multidisciplinary Sciences

Synthesis of proteins by automated flow chemistry

N. Hartrampf et al.

SCIENCE (2020)

Review Pharmacology & Pharmacy

Strategies for recombinant production of antimicrobial peptides with pharmacological potential

Kamila Botelho Sampaio de Oliveira et al.

EXPERT REVIEW OF CLINICAL PHARMACOLOGY (2020)

Review Microbiology

Critical analysis of antibacterial agents in clinical development

Ursula Theuretzbacher et al.

NATURE REVIEWS MICROBIOLOGY (2020)

Review Biotechnology & Applied Microbiology

Antimicrobial peptides as therapeutic agents: opportunities and challenges

Margit Mahlapuu et al.

CRITICAL REVIEWS IN BIOTECHNOLOGY (2020)

Article Biochemistry & Molecular Biology

Antimicrobial Peptides Display Strong Synergy with Vancomycin Against Vancomycin-Resistant E. faecium, S. aureus, and Wild-Type E. coli

Chih-Lung Wu et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2020)

Review Infectious Diseases

The value of antimicrobial peptides in the age of resistance

Maria Magana et al.

LANCET INFECTIOUS DISEASES (2020)

Review Biochemistry & Molecular Biology

Antimicrobial Peptides as Anticancer Agents: Functional Properties and Biological Activities

Anna Lucia Tornesello et al.

MOLECULES (2020)

Article Multidisciplinary Sciences

An amphipathic peptide with antibiotic activity against multidrug-resistant Gram-negative bacteria

Alysha G. Elliott et al.

NATURE COMMUNICATIONS (2020)

Review Biochemistry & Molecular Biology

Anti-cancer peptides: classification, mechanism of action, reconstruction and modification

Mingfeng Xie et al.

OPEN BIOLOGY (2020)

Article Multidisciplinary Sciences

Defining principles that influence antimicrobial peptide activity against capsulated Klebsiella pneumoniae

Renee M. Fleeman et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2020)

Review Microbiology

Resistance Mechanisms to Antimicrobial Peptides in Gram-Positive Bacteria

Lucas Assoni et al.

FRONTIERS IN MICROBIOLOGY (2020)

Review Chemistry, Medicinal

Antimicrobial peptides (AMPs): a patent review (2015-2020)

Giannamaria Annunziato et al.

EXPERT OPINION ON THERAPEUTIC PATENTS (2020)

Review Engineering, Biomedical

Mode-of-Action of Antimicrobial Peptides: Membrane Disruption vs. Intracellular Mechanisms

Aurelie H. Benfield et al.

FRONTIERS IN MEDICAL TECHNOLOGY (2020)

Article Medicine, Research & Experimental

Antimicrobial peptides - Advances in development of therapeutic applications

Huy Xuan Luong et al.

LIFE SCIENCES (2020)

Article Infectious Diseases

Designed Antimicrobial Peptides for Topical Treatment of Antibiotic Resistant Acne Vulgaris

Kathryn W. Woodburn et al.

ANTIBIOTICS-BASEL (2020)

Review Biochemistry & Molecular Biology

Biological Properties, Current Applications and Potential Therapeautic Applications of Brevinin Peptide Superfamily

Fatemeh Zohrab et al.

INTERNATIONAL JOURNAL OF PEPTIDE RESEARCH AND THERAPEUTICS (2019)

Article Biochemistry & Molecular Biology

Fast and potent bactericidal membrane lytic activity of PaDBS1R1, a novel cationic antimicrobial peptide

Luz N. Irazazabal et al.

BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES (2019)

Review Biochemistry & Molecular Biology

Antimicrobial Peptides: Amphibian Host Defense Peptides

Jiri Patocka et al.

CURRENT MEDICINAL CHEMISTRY (2019)

Article Chemistry, Organic

Sustainability Challenges in Peptide Synthesis and Purification: From R&D to Production

Albert Isidro-Llobet et al.

JOURNAL OF ORGANIC CHEMISTRY (2019)

Review Chemistry, Multidisciplinary

Using chemical synthesis to optimise antimicrobial peptides in the fight against antimicrobial resistance

Freda F. Li et al.

PURE AND APPLIED CHEMISTRY (2019)

Review Chemistry, Multidisciplinary

Combating bacterial resistance by combination of antibiotics with antimicrobial peptides

Dean E. Sheard et al.

PURE AND APPLIED CHEMISTRY (2019)

Review Microbiology

Drug repurposing for antimicrobial discovery

Maya A. Farha et al.

NATURE MICROBIOLOGY (2019)

Review Biochemistry & Molecular Biology

Antimicrobial Peptides and Vaccine Development to Control Multi-Drug Resistant Bacteria

Piyush Baindara et al.

PROTEIN AND PEPTIDE LETTERS (2019)

Review Multidisciplinary Sciences

The challenge of antimicrobial resistance: What economics can contribute

Laurence S. J. Roope et al.

SCIENCE (2019)

Article Chemistry, Analytical

Antimicrobial peptide arrays for wide spectrum sensing of pathogenic bacteria

Eric Pardoux et al.

TALANTA (2019)

Article Biochemistry & Molecular Biology

Synergistic and antibiofilm activity of the antimicrobial peptide P5 against carbapenem-resistant Pseudomonas aeruginosa

Melina Martinez et al.

BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES (2019)

Article Biotechnology & Applied Microbiology

Design of stapled antimicrobial peptides that are stable, nontoxic and kill antibiotic-resistant bacteria in mice

Rida Mourtada et al.

NATURE BIOTECHNOLOGY (2019)

Editorial Material Microbiology

Combinatory Therapy Antimicrobial Peptide-Antibiotic to Minimize the Ongoing Rise of Resistance

Luis R. Pizzolato-Cezar et al.

FRONTIERS IN MICROBIOLOGY (2019)

Article Multidisciplinary Sciences

DRAMP 2.0, an updated data repository of antimicrobial peptides

Xinyue Kang et al.

SCIENTIFIC DATA (2019)

Article Multidisciplinary Sciences

Integrated evolutionary analysis reveals antimicrobial peptides with limited resistance

Reka Spohn et al.

NATURE COMMUNICATIONS (2019)

Article Multidisciplinary Sciences

The antimicrobial peptide ZY4 combats multidrug-resistant Pseudomonas aeruginosa and Acinetobacter baumannii infection

James Mwangi et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2019)

Review Microbiology

Mechanisms of Action for Antimicrobial Peptides With Antibacterial and Antibiofilm Functions

Nigare Raheem et al.

FRONTIERS IN MICROBIOLOGY (2019)

Review Zoology

Antimicrobial peptides: new hope in the war against multidrug resistance

James Mwangi et al.

ZOOLOGICAL RESEARCH (2019)

Review Biochemistry & Molecular Biology

Antimicrobial peptides under clinical investigation

Hye Been Koo et al.

PEPTIDE SCIENCE (2019)

Article Multidisciplinary Sciences

Cathelicidins PMAP-36, LL-37 and CATH-2 are similar peptides with different modes of action

Maaike R. Scheenstra et al.

SCIENTIFIC REPORTS (2019)

Review Biotechnology & Applied Microbiology

Drug repurposing: progress, challenges and recommendations

Sudeep Pushpakom et al.

NATURE REVIEWS DRUG DISCOVERY (2019)

Article Infectious Diseases

Prevention of ESKAPE pathogen biofilm formation by antimicrobial peptides WLBU2 and LL37

Qiao Lin et al.

INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS (2018)

Article Infectious Diseases

Surveillance for control of antimicrobial resistance

Evelina Tacconelli et al.

LANCET INFECTIOUS DISEASES (2018)

Article Microbiology

Antibiotic interceptors: Creating safe spaces for bacteria

Akshay Sabnis et al.

PLOS PATHOGENS (2018)

Review Pharmacology & Pharmacy

Antimicrobial Peptides and Their Therapeutic Potential for Bacterial Skin Infections and Wounds

Anja Pfalzgraff et al.

FRONTIERS IN PHARMACOLOGY (2018)

Review Biotechnology & Applied Microbiology

Breaking the frontiers of cosmetology with antimicrobial peptides

Thuany Alencar-Silva et al.

BIOTECHNOLOGY ADVANCES (2018)

Review Plant Sciences

The role of antimicrobial peptides in plant immunity

Marcelo Lattarulo Campos et al.

JOURNAL OF EXPERIMENTAL BOTANY (2018)

Review Biochemistry & Molecular Biology

Antimicrobial peptides from different plant sources: Isolation, characterisation, and purification

Swee-Seong Tang et al.

PHYTOCHEMISTRY (2018)

Article Chemistry, Medicinal

Effects of lysine-to-arginine substitution on antimicrobial activity of cationic stapled heptapeptides

Huy X. Luong et al.

ARCHIVES OF PHARMACAL RESEARCH (2018)

Article Microbiology

The cost of antimicrobial resistance

Ursula Hofer

NATURE REVIEWS MICROBIOLOGY (2018)

Article Chemistry, Multidisciplinary

C-Terminal Modification and Multimerization Increase the Efficacy of a Proline-Rich Antimicrobial Peptide

Wenyi Li et al.

CHEMISTRY-A EUROPEAN JOURNAL (2017)

Review Dermatology

Friends or Foes? Host defense (antimicrobial) peptides and proteins in human skin diseases

Francois Niyonsaba et al.

EXPERIMENTAL DERMATOLOGY (2017)

Review Infectious Diseases

Antimicrobial potential of bacteriocins: in therapy, agriculture and food preservation

Varish Ahmad et al.

INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS (2017)

Article Biochemistry & Molecular Biology

A fully automated flow-based approach for accelerated peptide synthesis

Alexander J. Mijalis et al.

NATURE CHEMICAL BIOLOGY (2017)

Review Neurosciences

Membrane Active Antimicrobial Peptides: Translating Mechanistic Insights to Design

Jianguo Li et al.

FRONTIERS IN NEUROSCIENCE (2017)

Review Chemistry, Multidisciplinary

Antimicrobial Peptides in Biomedical Device Manufacturing

Martijn Riool et al.

FRONTIERS IN CHEMISTRY (2017)

Article Biochemistry & Molecular Biology

Antimicrobial peptides are degraded by the cytosolic proteases of human erythrocytes

Charles G. Starr et al.

BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES (2017)

Article Biochemistry & Molecular Biology

The random co-polymer glatiramer acetate rapidly kills primary human leukocytes through sialic-acid-dependent cell membrane damage

Stig Hill Christiansen et al.

BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES (2017)

Article Chemistry, Medicinal

Antimicrobial activity and stability of stapled helices of polybia-MP1

Huy X. Luong et al.

ARCHIVES OF PHARMACAL RESEARCH (2017)

Review Pharmacology & Pharmacy

Antimicrobial peptides (AMPs): Ancient compounds that represent novel weapons in the fight against bacteria

J. M. Ageitos et al.

BIOCHEMICAL PHARMACOLOGY (2017)

Review Microbiology

Intracellular Targeting Mechanisms by Antimicrobial Peptides

Cheng-Foh Le et al.

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2017)

Article Infectious Diseases

NLF20: an antimicrobial peptide with therapeutic potential against invasive Pseudomonas aeruginosa infection

Praveen Papareddy et al.

JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY (2016)

Article Biochemistry & Molecular Biology

CAMPR3: a database on sequences, structures and signatures of antimicrobial peptides

Faiza Hanif Waghu et al.

NUCLEIC ACIDS RESEARCH (2016)

Article Biochemistry & Molecular Biology

DBAASP v.2: an enhanced database of structure and antimicrobial/cytotoxic activity of natural and synthetic peptides

Malak Pirtskhalava et al.

NUCLEIC ACIDS RESEARCH (2016)

Article Biochemistry & Molecular Biology

APD3: the antimicrobial peptide database as a tool for research and education

Guangshun Wang et al.

NUCLEIC ACIDS RESEARCH (2016)

Article Biochemistry & Molecular Biology

The interfacial properties of the peptide Polybia-MP1 and its interaction with DPPC are modulated by lateral electrostatic attractions

Dayane S. Alvares et al.

BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES (2016)

Article Biochemistry & Molecular Biology

Peptides with dual mode of action: Killing bacteria and preventing endotoxin-induced sepsis

Klaus Brandenburg et al.

BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES (2016)

Article Biochemistry & Molecular Biology

The human cathelicidin LL-37 A pore-forming antibacterial peptide and host-cell modulator

Daniela Xhindoli et al.

BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES (2016)

Editorial Material Biochemistry & Molecular Biology

Antimicrobial peptides

Ling-juan Zhang et al.

CURRENT BIOLOGY (2016)

Review Pharmacology & Pharmacy

Mechanisms and consequences of bacterial resistance to antimicrobial peptides

D. I. Andersson et al.

DRUG RESISTANCE UPDATES (2016)

Review Biophysics

The effect of amidation on the behaviour of antimicrobial peptides

Manuela Mura et al.

EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS (2016)

Review Dermatology

Antimicrobial peptides and wound healing: biological and therapeutic considerations

Maria Luisa Mangoni et al.

EXPERIMENTAL DERMATOLOGY (2016)

Review Biotechnology & Applied Microbiology

Biomedical applications of nisin

J. M. Shin et al.

JOURNAL OF APPLIED MICROBIOLOGY (2016)

Article Food Science & Technology

Bacteriocins from lactic acid bacteria and their applications in meat and meat products

Weerapong Woraprayote et al.

MEAT SCIENCE (2016)

Review Biology

Bacterial strategies of resistance to antimicrobial peptides

Hwang-Soo Joo et al.

PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES (2016)

Article Multidisciplinary Sciences

Use of recombinant porcine β-defensin 2 as a medicated feed additive for weaned piglets

Zixin Peng et al.

SCIENTIFIC REPORTS (2016)

Article Multidisciplinary Sciences

DRAMP: a comprehensive data repository of antimicrobial peptides

Linlin Fan et al.

SCIENTIFIC REPORTS (2016)

Review Biochemistry & Molecular Biology

Antimicrobial Peptides as Potential Alternatives to Antibiotics in Food Animal Industry

Shuai Wang et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2016)

Review Biotechnology & Applied Microbiology

Short antimicrobial peptides as cosmetic ingredients to deter dermatological pathogens

Mohammad Rahnamaeian et al.

APPLIED MICROBIOLOGY AND BIOTECHNOLOGY (2015)

Review Biochemistry & Molecular Biology

Cationic antimicrobial peptide resistance mechanisms of streptococcal pathogens

Christopher N. LaRock et al.

BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES (2015)

Article Biophysics

The Structure of a Melittin-Stabilized Pore

John M. Leveritt et al.

BIOPHYSICAL JOURNAL (2015)

Review Chemistry, Medicinal

Membrane-Active Small Molecules: Designs Inspired by Antimicrobial Peptides

Chandradhish Ghosh et al.

CHEMMEDCHEM (2015)

Article Biochemistry & Molecular Biology

Structural insights into Cn-AMP1, a short disulfide-free multifunctional peptide from green coconut water

Mabio J. Santana et al.

FEBS LETTERS (2015)

Article Immunology

Inhibition of Outer Membrane Proteases of the Omptin Family by Aprotinin

John R. Brannon et al.

INFECTION AND IMMUNITY (2015)

Article Biology

Antimicrobial resistance in humans, livestock and the wider environment

Mark Woolhouse et al.

PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES (2015)

Review Agriculture, Dairy & Animal Science

The application of antimicrobial peptides as growth and health promoters for swine

Hao Xiao et al.

JOURNAL OF ANIMAL SCIENCE AND BIOTECHNOLOGY (2015)

Article Multidisciplinary Sciences

Antimicrobial and antioxidant properties of the crude peptide extracts of Galatea paradoxa and Patella rustica

Lawrence Sheringham Borquaye et al.

SPRINGERPLUS (2015)

Article Chemistry, Multidisciplinary

Insect-Derived Proline-Rich Antimicrobial Peptides Kill Bacteria by Inhibiting Bacterial Protein Translation at the 70S Ribosome

Andor Krizsan et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2014)

Review Biotechnology & Applied Microbiology

Insect antimicrobial peptides and their applications

Hui-Yu Yi et al.

APPLIED MICROBIOLOGY AND BIOTECHNOLOGY (2014)

Review Biotechnology & Applied Microbiology

Challenges and opportunities in the purification of recombinant tagged proteins

Ana Sofia Pina et al.

BIOTECHNOLOGY ADVANCES (2014)

Article Chemistry, Multidisciplinary

De Novo Design and Their Antimicrobial Activity of Stapled Amphipathic Helices of Heptapeptides

Thuy T. T. Dinh et al.

BULLETIN OF THE KOREAN CHEMICAL SOCIETY (2014)

Article Biochemistry & Molecular Biology

The Host Antimicrobial Peptide Bac71-35 Binds to Bacterial Ribosomal Proteins and Inhibits Protein Synthesis

Mario Mardirossian et al.

CHEMISTRY & BIOLOGY (2014)

Article Dermatology

Will the wound-healing field earn its wings?

Aimee E. Anderson et al.

EXPERIMENTAL DERMATOLOGY (2014)

Article Biochemistry & Molecular Biology

A potential wound-healing-promoting peptide from salamander skin

Lixian Mu et al.

FASEB JOURNAL (2014)

Article Plant Sciences

Antimicrobial Peptides from Skin Secretions of Hypsiboas pulchellus (Anura: Hylidae)

Alvaro Siano et al.

JOURNAL OF NATURAL PRODUCTS (2014)

Review Chemistry, Medicinal

Avian Antimicrobial Host Defense Peptides: From Biology to Therapeutic Applications

Guolong Zhang et al.

PHARMACEUTICALS (2014)

Review Chemistry, Medicinal

Antimicrobial Peptides from Fish

Jorge A. Masso-Silva et al.

PHARMACEUTICALS (2014)

Article Biochemistry & Molecular Biology

Rapid bactericidal action of alpha-mangostin against MRSA as an outcome of membrane targeting

Jun-Jie Koh et al.

BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES (2013)

Article Biochemistry & Molecular Biology

Characterization of a Proteolytically Stable Multifunctional Host Defense Peptidomimetic

Rasmus D. Jahnsen et al.

CHEMISTRY & BIOLOGY (2013)

Review Microbiology

Bacterial resistance to cationic antimicrobial peptides

Jose Luis Anaya-Lopez et al.

CRITICAL REVIEWS IN MICROBIOLOGY (2013)

Article Multidisciplinary Sciences

LAMP: A Database Linking Antimicrobial Peptides

Xiaowei Zhao et al.

PLOS ONE (2013)

Article Multidisciplinary Sciences

De-Novo Design of Antimicrobial Peptides for Plant Protection

Benjamin Zeitler et al.

PLOS ONE (2013)

Article Multidisciplinary Sciences

A Small Peptide with Therapeutic Potential for Inflammatory Acne Vulgaris

Zhiye Zhang et al.

PLOS ONE (2013)

Article Multidisciplinary Sciences

Derivatives of the Antimicrobial Peptide BP100 for Expression in Plant Systems

Esther Badosa et al.

PLOS ONE (2013)

Article Biochemistry & Molecular Biology

Does cholesterol suppress the antimicrobial peptide induced disruption of lipid raft containing membranes?

Austin J. McHenry et al.

BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES (2012)

Article Biochemistry & Molecular Biology

Characterization of dual effects induced by antimicrobial peptides: Regulated cell death or membrane disruption

Edgar J. Paredes-Gamero et al.

BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS (2012)

Article Biochemistry & Molecular Biology

Cn-AMP1: A new promiscuous peptide with potential for microbial infections treatment

Osmar N. Silva et al.

BIOPOLYMERS (2012)

Review Microbiology

Resistance to antimicrobial peptides in Gram-negative bacteria

Samantha Gruenheid et al.

FEMS MICROBIOLOGY LETTERS (2012)

Article Infectious Diseases

YADAMP: yet another database of antimicrobial peptides

Stefano P. Piotto et al.

INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS (2012)

Review Biotechnology & Applied Microbiology

Natural antimicrobial peptides from bacteria: characteristics and potential applications to fight against antibiotic resistance

M. Hassan et al.

JOURNAL OF APPLIED MICROBIOLOGY (2012)

Article Chemistry, Multidisciplinary

Synthetic Mimics of Antimicrobial Peptides with Immunomodulatory Responses

Hitesh D. Thaker et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2012)

Article Biochemical Research Methods

Lactoferricin B Inhibits the Phosphorylation of the Two-Component System Response Regulators BasR and CreB

Yu-Hsuan Ho et al.

MOLECULAR & CELLULAR PROTEOMICS (2012)

Review Food Science & Technology

Bioactive peptides from marine processing waste and shellfish: A review

Padraigin A. Harnedy et al.

JOURNAL OF FUNCTIONAL FOODS (2012)

Editorial Material Immunology

Does cholesterol play a role in the bacterial selectivity of antimicrobial peptides?

Jeffrey R. Brender et al.

FRONTIERS IN IMMUNOLOGY (2012)

Review Biotechnology & Applied Microbiology

The expanding scope of antimicrobial peptide structures and their modes of action

Leonard T. Nguyen et al.

TRENDS IN BIOTECHNOLOGY (2011)

Article Microbiology

Human Antimicrobial Peptide LL-37 Induces MefE/Mel-Mediated Macrolide Resistance in Streptococcus pneumoniae

Dorothea Zaehner et al.

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2010)

Article Microbiology

Antimicrobial Activity of a Halocidin-Derived Peptide Resistant to Attacks by Proteases

Yong Pyo Shin et al.

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2010)

Article Biochemistry & Molecular Biology

Cholesterol reduces pardaxin's dynamics-a barrel-stave mechanism of membrane disruption investigated by solid-state NMR

Ayyalusamy Ramamoorthy et al.

BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES (2010)

Article Infectious Diseases

The antimicrobial peptide Ci-MAM-A24 is highly active against multidrug-resistant and anaerobic bacteria pathogenic for humans

Henning Fedders et al.

INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS (2010)

Review Biochemistry & Molecular Biology

The dermaseptin superfamily: A gene-based combinatorial library of antimicrobial peptides

Pierre Nicolas et al.

BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES (2009)

Review Biochemistry & Molecular Biology

Antimicrobial peptide mimics for improved therapeutic properties

Shahar Rotem et al.

BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES (2009)

Review Biochemistry & Molecular Biology

Anionic Antimicrobial Peptides from Eukaryotic Organisms

Frederick Harris et al.

CURRENT PROTEIN & PEPTIDE SCIENCE (2009)

Article Biochemistry & Molecular Biology

The Proline-rich Antibacterial Peptide Bac7 Binds to and Inhibits in vitro the Molecular Chaperone DnaK

Marco Scocchi et al.

INTERNATIONAL JOURNAL OF PEPTIDE RESEARCH AND THERAPEUTICS (2009)

Review Biotechnology & Applied Microbiology

Potential of immunomodulatory host defense peptides as novel anti-infectives

Donna M. Easton et al.

TRENDS IN BIOTECHNOLOGY (2009)

Review Food Science & Technology

Nisin biotechnological production and application: a review

Luciana Juncioni de Arauz et al.

TRENDS IN FOOD SCIENCE & TECHNOLOGY (2009)

Article Biochemistry & Molecular Biology

Synthetic Mimic of Antimicrobial Peptide with Nonmembrane-Disrupting Antibacterial Properties

Gregory J. Gabriel et al.

BIOMACROMOLECULES (2008)

Review Biochemical Research Methods

De novo designed synthetic mimics of antimicrobial peptides

Richard W. Scott et al.

CURRENT OPINION IN BIOTECHNOLOGY (2008)

Article Biochemistry & Molecular Biology

A library of linear undecapeptides with bactericidal activity against phytopathogenic bacteria

Esther Badosa et al.

PEPTIDES (2007)

Article Biochemistry & Molecular Biology

Hydrophobic interactions in complexes of antimicrobial peptides with bacterial polysaccharides

Hsin H. Kuo et al.

CHEMICAL BIOLOGY & DRUG DESIGN (2007)

Review Biochemistry & Molecular Biology

Omptin proteins: an expanding family of outer membrane proteases in Gram-negative Enterobacteriaceae

Victoria Hritonenko et al.

MOLECULAR MEMBRANE BIOLOGY (2007)

Article Chemistry, Analytical

Antimicrobial peptides for detection of bacteria in biosensor assays

NV Kulagina et al.

ANALYTICAL CHEMISTRY (2005)

Article Biochemistry & Molecular Biology

Structural aspects and biological properties of the cathelicidin PMAP-36

M Scocchi et al.

FEBS JOURNAL (2005)

Article Biochemical Research Methods

Alginate as an auxiliary bacterial membrane: binding of membrane-active peptides by polysaccharides

C Chan et al.

JOURNAL OF PEPTIDE RESEARCH (2005)

Article Microbiology

Degradation of human antimicrobial peptide LL-37 by Staphylococcus aureus-derived proteinases

M Sieprawska-Lupa et al.

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2004)

Letter Chemistry, Medicinal

The pharmacophore of short cationic antibacterial peptides

MB Strom et al.

JOURNAL OF MEDICINAL CHEMISTRY (2003)

Article Dentistry, Oral Surgery & Medicine

Safety and clinical effects of topical histatin gels in humans with experimental gingivitis

DW Paquette et al.

JOURNAL OF CLINICAL PERIODONTOLOGY (2002)

Article Biochemistry & Molecular Biology

Structure and mechanism of action of an indolicidin peptide derivative with improved activity against gram-positive bacteria

CL Friedrich et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2001)

Article Biotechnology & Applied Microbiology

Design of self-processing antimicrobial peptides for plant protection

WA Powell et al.

LETTERS IN APPLIED MICROBIOLOGY (2000)