4.6 Article

Heart Rate Variability in Schizophrenia and Autism

期刊

FRONTIERS IN PSYCHIATRY
卷 12, 期 -, 页码 -

出版社

FRONTIERS MEDIA SA
DOI: 10.3389/fpsyt.2021.760396

关键词

autism; schizophrenia; heart rate variability; electrocardiography; autonomic functioning

资金

  1. NARSAD Young Investigator Grant from the Brain and Behavior Research Foundation [26282]
  2. National Institute of Mental Health [122935]
  3. NSF EPSCoR grant [1632849]

向作者/读者索取更多资源

In this study, suppressed HRV was found in adults with schizophrenia compared to controls, while those with autism showed slightly reduced HRV but no significant difference. The autism group reported feeling lonelier than the schizophrenia group, and HRV did not correlate with loneliness in any of the groups. However, in the schizophrenia group, suppressed HRV was linked to poorer performance on neuropsychological tests. This suggests that autonomic functioning abnormalities are more pronounced in schizophrenia than in autism and may reflect unique health factors associated with schizophrenia.
Suppressed heart rate variability (HRV) has been found in a number of psychiatric conditions, including schizophrenia and autism. HRV is a potential biomarker of altered autonomic functioning that can predict future physiological and cognitive health. Understanding the HRV profiles that are unique to each condition will assist in generating predictive models of health. In the current study, we directly compared 12 adults with schizophrenia, 25 adults with autism, and 27 neurotypical controls on their HRV profiles. HRV was measured using an electrocardiogram (ECG) channel as part of a larger electroencephalography (EEG) study. All participants also completed the UCLA Loneliness Questionnaire as a measure of social stress. We found that the adults with schizophrenia exhibited reduced variability in R-R peaks and lower low frequency power in the ECG trace compared to controls. The HRV in adults with autism was slightly suppressed compared to controls but not significantly so. Interestingly, the autism group reported feeling lonelier than the schizophrenia group, and HRV did not correlate with feelings of loneliness for any of the three groups. However, suppressed HRV was related to worse performance on neuropsychological tests of cognition in the schizophrenia group. Together, this suggests that autonomic functioning is more abnormal in schizophrenia than in autism and could be reflecting health factors that are unique to schizophrenia.

作者

我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。

评论

主要评分

4.6
评分不足

次要评分

新颖性
-
重要性
-
科学严谨性
-
评价这篇论文

推荐

暂无数据
暂无数据