☆ 4.6 Article

The Construction of a Prognostic Model Based on a Peptidyl Prolyl Cis-Trans Isomerase Gene Signature in Hepatocellular Carcinoma

FRONTIERS IN GENETICS (2021)

相关参考文献

注意：仅列出部分参考文献，下载原文获取全部文献信息。

Article Cell Biology

Prognostic model and nomogram construction based on autophagy signatures in lower grade glioma

Chunhui Wang et al.

Summary: The study established a prognostic risk score model based on seven ATG genes for LGG, showing significant differences in overall survival between high and low risk patients. The final prognostic model, incorporating age, WHO grade, 1p19q codeletion status, and ATG risk score, was validated as an independent prognostic indicator and a nomogram for individualized survival prediction.

JOURNAL OF CELLULAR PHYSIOLOGY (2021)

添加到收藏夹

Article Medicine, General & Internal

Hepatocellular carcinoma

Josep M. Llovet et al.

Summary: Liver cancer, particularly hepatocellular carcinoma (HCC), poses a significant global health challenge with rising incidence projected to exceed 1 million cases by 2025. Infection by hepatitis B and C viruses remains a major risk factor for HCC, while non-alcoholic steatohepatitis is emerging as a more common risk factor in Western countries. Advances in systemic therapies for HCC, including immunotherapies and targeted therapies, are expected to revolutionize the management of this disease.

NATURE REVIEWS DISEASE PRIMERS (2021)

添加到收藏夹

Article Oncology

A prognostic nomogram based on LASSO Cox regression in patients with alpha-fetoprotein-negative hepatocellular carcinoma following non-surgical therapy

Dongdong Zhou et al.

Summary: The novel nomogram based on LASSO Cox regression provides more accurate and useful prognostic prediction for patients with AFP-NHCC following non-surgical therapy, facilitating personalized prognostic evaluation.

BMC CANCER (2021)

添加到收藏夹

Article Oncology

Global cancer statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries

Hyuna Sung et al.

Summary: The global cancer burden in 2020 saw an estimated 19.3 million new cancer cases and almost 10.0 million cancer deaths. Female breast cancer surpassed lung cancer as the most commonly diagnosed cancer, while lung cancer remained the leading cause of cancer death. These trends are expected to rise in 2040, with transitioning countries experiencing a larger increase compared to transitioned countries due to demographic changes and risk factors associated with globalization and a growing economy. Efforts to improve cancer prevention measures and provision of cancer care in transitioning countries will be crucial for global cancer control.

CA-A CANCER JOURNAL FOR CLINICIANS (2021)

添加到收藏夹

Article Oncology

Nomogram for Predicting the Prognosis of Patients with Hepatocellular Carcinoma Presenting with Pulmonary Metastasis

Yongjie Zhou et al.

Summary: This study evaluated the prevalence, risk factors, and prognostic factors related to pulmonary metastasis in patients with hepatocellular carcinoma (HCC) at the initial diagnosis, and constructed a nomogram to predict patient outcomes. The nomogram accurately predicted prognosis and included factors such as sex, T stage, bone metastasis, AFP levels, treatment, radiation, and chemotherapy.

CANCER MANAGEMENT AND RESEARCH (2021)

添加到收藏夹

Article Oncology

Nomogram Based on Ultrasonography and Clinical Features for Predicting Malignancy in Soft Tissue Tumors

Mengjie Wu et al.

Summary: The study developed a predictive nomogram for soft tissue tumor patients based on ultrasound and clinical features, showing good accuracy and discrimination in predicting malignancy with high sensitivity and specificity.

CANCER MANAGEMENT AND RESEARCH (2021)

添加到收藏夹

Article Oncology

Development of an Autophagy-Related Gene Prognostic Model and Nomogram for Estimating Renal Clear Cell Carcinoma Survival

Ying Wang et al.

Summary: The study evaluated the prognostic value of autophagy-related genes in kidney renal clear cell carcinoma (KIRC) and developed an ARG prognostic signature using gene analysis and clinical data. The ARG nomogram showed proper calibration and discrimination in predicting KIRC prognosis, indicating potential clinical usefulness.

JOURNAL OF ONCOLOGY (2021)

添加到收藏夹

Article Biotechnology & Applied Microbiology

m6A RNA Methylation Regulators Elicit Malignant Progression and Predict Clinical Outcome in Hepatocellular Carcinoma

Wenli Li et al.

Summary: The expression levels of m(6)A RNA methylation regulators are correlated with clinical characteristics in HCC patients, and a signature based on these regulators can effectively stratify high-risk patients and predict prognosis. Immune cell analysis and functional enrichment suggest the involvement of these regulators in genetic and epigenetic events linked to HCC. The constructed nomogram incorporating the signature and clinicopathological factors demonstrates good performance in predicting overall survival in HCC patients.

DISEASE MARKERS (2021)

添加到收藏夹

Article Oncology

A Tumor Progression Related 7-Gene Signature Indicates Prognosis and Tumor Immune Characteristics of Gastric Cancer

Fen Liu et al.

Summary: Using WGCNA, the study identified hub genes related to gastric cancer progression, constructed a gastric cancer risk model, and identified high-risk patients, demonstrating that the risk score can be used as an independent prognostic factor for gastric cancer. High-risk patients had poorer prognosis and more immune characteristics suitable for immunotherapy.

FRONTIERS IN ONCOLOGY (2021)

添加到收藏夹

Article Biochemistry & Molecular Biology

Development and validation of autophagy-related-gene biomarker and nomogram for predicting the survival of cutaneous melanoma

Qi Wan et al.

IUBMB LIFE (2020)

添加到收藏夹

Review Gastroenterology & Hepatology

Advances in resection and transplantation for hepatocellular carcinoma

Eric Vibert et al.

JOURNAL OF HEPATOLOGY (2020)

添加到收藏夹

Article Oncology

Prognostic value of an autophagy-related gene expression signature for endometrial cancer patients

Hui Wang et al.

CANCER CELL INTERNATIONAL (2020)

添加到收藏夹

Review Medicine, General & Internal

New advances in the diagnosis and management of hepatocellular carcinoma

Ju Dong Yang et al.

BMJ-BRITISH MEDICAL JOURNAL (2020)

添加到收藏夹

Review Pharmacology & Pharmacy

FK506 binding proteins and inflammation related signalling pathways; basic biology, current status and future prospects for pharmacological intervention

Stephanie Annett et al.

PHARMACOLOGY & THERAPEUTICS (2020)

添加到收藏夹

Article Genetics & Heredity

LncRNA SNHG15 acts as an oncogene in prostate cancer by regulating miR-338-3p/FKBP1A axis

Yuelong Zhang et al.

GENE (2019)

添加到收藏夹

Article Oncology

External Replication of Urinary Bladder Cancer Prognostic Polymorphisms in the UK Biobank

Nadezda Lipunova et al.

FRONTIERS IN ONCOLOGY (2019)

添加到收藏夹

Editorial Material Biochemistry & Molecular Biology

SnapShot: TCGA-Analyzed Tumors

Amy Blum et al.

CELL (2018)

添加到收藏夹

Review Medicine, General & Internal

Hepatocellular carcinoma

Alejandro Forner et al.

LANCET (2018)

添加到收藏夹

Article Biochemistry & Molecular Biology

Gene set selection via LASSO penalized regression ( SLPR)

H. Robert Frost et al.

NUCLEIC ACIDS RESEARCH (2017)

添加到收藏夹

Review Surgery

A Review and Update of Treatment Options and Controversies in the Management of Hepatocellular Carcinoma

Mashaal Dhir et al.

ANNALS OF SURGERY (2016)

添加到收藏夹

Article Biochemistry & Molecular Biology

Genome-wide methylation profiling reveals Zinc finger protein 516 (ZNF516) and FK-506binding protein 6 (FKBP6) promoters frequently methylated in cervical neoplasia, associated with HPV status and ethnicity in a Chilean population

Priscilla Brebi et al.

EPIGENETICS (2014)

添加到收藏夹

Article Gastroenterology & Hepatology

Hepatocellular carcinoma: clinical frontiers and perspectives

Jordi Bruix et al.

GUT (2014)

添加到收藏夹

Article Biochemical Research Methods

Molecular signatures database (MSigDB) 3.0

Arthur Liberzon et al.

BIOINFORMATICS (2011)

添加到收藏夹

Article Biochemistry & Molecular Biology

FKBP51 Promotes Assembly of the Hsp90 Chaperone Complex and Regulates Androgen Receptor Signaling in Prostate Cancer Cells

Li Ni et al.

MOLECULAR AND CELLULAR BIOLOGY (2010)

添加到收藏夹

Article Hematology

The effect of FK506 on transforming growth factor β signaling and apaptosis in chronic lymphocytic leukemia B cells

Simona Romano et al.

HAEMATOLOGICA-THE HEMATOLOGY JOURNAL (2008)

添加到收藏夹

Article Oncology

How to build and interpret a nomogram for cancer prognosis

Alexia Iasonos et al.

JOURNAL OF CLINICAL ONCOLOGY (2008)

添加到收藏夹

Review Biochemistry & Molecular Biology

Prolyl cis-trans isomerization as a molecular timer

Kun Ping Lu et al.

NATURE CHEMICAL BIOLOGY (2007)

添加到收藏夹

Article Biochemistry & Molecular Biology

The protein phosphatase 2A phosphatase activator is a novel peptidyl-prolyl cis/trans-isomerase

J Jordens et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2006)

添加到收藏夹

Review Biochemistry & Molecular Biology

Insights into the catalytic mechanism of peptidyl prolyl cis/trans isomerases

J Fanghänel et al.

FRONTIERS IN BIOSCIENCE-LANDMARK (2004)

添加到收藏夹

Article Pathology

Prevalent overexpression of prolyl isomerase Pin1 in human cancers

L Bao et al.

AMERICAN JOURNAL OF PATHOLOGY (2004)

添加到收藏夹

© Peeref 2019-2024. All rights reserved.