相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。Huntingtin and Its Role in Mechanisms of RNA-Mediated Toxicity
Annika Heinz et al.
TOXINS (2021)
Reducing Mutant Huntingtin Protein Expression in Living Cells by a Newly Identified RNA CAG Binder
Frank Matthes et al.
ACS CHEMICAL NEUROSCIENCE (2018)
Pharmacological disruption of the MID1/α4 interaction reduces mutant Huntingtin levels in primary neuronal cultures
Olivia Monteiro et al.
NEUROSCIENCE LETTERS (2018)
MicroRNAs miR-19, miR-340, miR-374 and miR-542 regulate MID1 protein expression
Kristoffer Unterbruner et al.
PLOS ONE (2018)
Metformin reverses early cortical network dysfunction and behavior changes in Huntington's disease
Isabelle Arnoux et al.
ELIFE (2018)
Inhibition of the MID1 protein complex: a novel approach targeting APP protein synthesis
Frank Matthes et al.
CELL DEATH DISCOVERY (2018)
Resveratrol induces dephosphorylation of Tau by interfering with the MID1-PP2A complex
Susann Schweiger et al.
SCIENTIFIC REPORTS (2017)
The MID1 protein is a central player during development and in disease
Jennifer Winter et al.
FRONTIERS IN BIOSCIENCE-LANDMARK (2016)
Regulation of mRNA Translation by MID1: A Common Mechanism of Expanded CAG Repeat RNAs
Nadine Griesche et al.
FRONTIERS IN CELLULAR NEUROSCIENCE (2016)
TNF-related apoptosis-inducing ligand (TRAIL) regulates midline-1, thymic stromal lymphopoietin, inflammation, and remodeling in experimental eosinophilic esophagitis
Adam M. Collison et al.
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY (2015)
A hormone-dependent feedback-loop controls androgen receptor levels by limiting MID1, a novel translation enhancer and promoter of oncogenic signaling
Andrea Koehler et al.
MOLECULAR CANCER (2014)
The Anti-Diabetic Drug Metformin Reduces BACE1 Protein Level by Interfering with the MID1 Complex
Moritz M. Hettich et al.
PLOS ONE (2014)
Rational design of antisense oligonucleotides targeting single nucleotide polymorphisms for potent and allele selective suppression of mutant Huntingtin in the CNS
Michael E. Ostergaard et al.
NUCLEIC ACIDS RESEARCH (2013)
Mechanisms of RNA-induced toxicity in CAG repeat disorders
R. Nalavade et al.
CELL DEATH & DISEASE (2013)
Translation of HTT mRNA with expanded CAG repeats is regulated by the MID1-PP2A protein complex
Sybille Krauss et al.
NATURE COMMUNICATIONS (2013)
Sustained Therapeutic Reversal of Huntington's Disease by Transient Repression of Huntingtin Synthesis
Holly B. Kordasiewicz et al.
NEURON (2012)
Reduced Mid1 expression and delayed neuromotor development in daDREAM transgenic mice
Mara Dierssen et al.
FRONTIERS IN MOLECULAR NEUROSCIENCE (2012)
Mutant CAG repeats of Huntingtin transcript fold into hairpins, form nuclear foci and are targets for RNA interference
Mateusz de Mezer et al.
NUCLEIC ACIDS RESEARCH (2011)
Control of mTORC1 signaling by the Opitz syndrome protein MID1
Enbo Liu et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
Atomic resolution structure of CAG RNA repeats: structural insights and implications for the trinucleotide repeat expansion diseases
Agnieszka Kiliszek et al.
NUCLEIC ACIDS RESEARCH (2010)
Biguanide metformin acts on tau phosphorylation via mTOR/protein phosphatase 2A (PP2A) signaling
Eva Kickstein et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
TRIM/RBCC, a novel class of 'single protein RING finger' E3 ubiquitin ligases
G Meroni et al.
BIOESSAYS (2005)
CAG repeats containing CAA interruptions form branched hairpin structures in spinocerebellar ataxia type 2 transcripts
K Sobczak et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
RNA structure of trinucleotide repeats associated with human neurological diseases
K Sobczak et al.
NUCLEIC ACIDS RESEARCH (2003)
MID1, mutated in Opitz syndrome, encodes an ubiquitin ligase that targets phosphatase 2A for degradation
A Trockenbacher et al.
NATURE GENETICS (2001)