4.6 Article

The MID1 Protein: A Promising Therapeutic Target in Huntington's Disease

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Summary: Huntington's disease is caused by a CAG-repeat expansion mutation in the Huntingtin gene, leading to progressive psychiatric and neurological symptoms. Recent studies indicate the contribution of mutant RNA transcript to cellular dysfunction besides the protein encoded by the HTT gene. Therapeutic approaches targeting the mutant HTT transcript offer hope for better treatment outcomes.

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