Recent advances in catalytic enantioselective direct C-H bond functionalization of electron-deficient N-containing heteroarenes

Catalytic enantioselective direct C-H bond functionalization of electron-deficient N-containing heteroarenes represents one of the most straightforward and powerful protocols to construct diverse enantioenriched highly functionalized N-heteroarene products. Efficient catalytic systems and a variety of strategies for highly chemo- and stereoselective C-H functionalization of electron-deficient N-containing heteroarenes have been developed over the past few decades. This review summarized the rapid progress in the catalytic asymmetric C-H functionalization of N-containing heteroarenes and discussed the challenges and potential of the field in the current stage.

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This review summarizes the rapid progress in the catalytic asymmetric C-H functionalization of N-containing heteroarenes and discusses the challenges and potential of the field in the current stage.