Inverse problem solver for multiple light scattering using modified Born series

The inverse scattering problem, whose goal is to reconstruct an unknown scattering object from its scattered wave, is essential in fundamental wave physics and its wide applications in imaging sciences. However, it remains challenging to invert multiple scattering accurately and efficiently. Here, we exploit the modified Born series to demonstrate an inverse problem solver that efficiently and directly computes inverse multiple scattering without making any assumptions. The inversion process is based on a physically intuitive approach and can be easily extended to other exact forward solvers. We utilize the proposed method in optical diffraction tomography and numerically and experimentally demonstrate 3D reconstruction of optically thick specimens with higher fidelity than those obtained using conventional methods based on the weak scattering approximation. (C) 2022 Optica Publishing Group under the terms of the Optica Open Access Publishing Agreement

Automated summary

The inverse scattering problem is crucial in fundamental wave physics and imaging sciences, but accurately and efficiently inverting multiple scattering remains challenging. In this study, we propose an inverse problem solver based on the modified Born series, which allows for efficient and direct computation of inverse multiple scattering without any assumptions. We apply this method to optical diffraction tomography and demonstrate numerically and experimentally the 3D reconstruction of optically thick specimens with higher fidelity than conventional methods based on the weak scattering approximation.