4.6 Review

Cerebral Microcirculation, Perivascular Unit, and Glymphatic System: Role of Aquaporin-4 as the Gatekeeper for Water Homeostasis

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Three distinct roles of aquaporin-4 in brain function revealed by knockout mice

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Aquaporin-4 gene deletion in mice increases focal edema associated with staphylococcal brain abscess

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Aquaporin-4 gene disruption in mice reduces brain swelling and mortality in pneumococcal meningitis

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JOURNAL OF BIOLOGICAL CHEMISTRY (2005)

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Loss of perivascular aquaporin 4 may underlie deficient water and K+ homeostasis in the human epileptogenic hippocampus

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Review Cell Biology

From structure to disease: The evolving tale of aquaporin biology

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NATURE REVIEWS MOLECULAR CELL BIOLOGY (2004)

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Aquaporin-4 is increased in the sclerotic hippocampus in human temporal lobe epilepsy

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ACTA NEUROPATHOLOGICA (2004)

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Aquaporin-4 facilitates reabsorption of excess fluid in vasogenic brain edema

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FASEB JOURNAL (2004)

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Delayed K+ clearance associated with aquaporin-4 mislocalization:: Phenotypic defects in brains of α-syntrophin-null mice

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PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)

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Aquaporin-4 square array assembly: Opposing actions of M1 and M23 isoforms

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PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)

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An α-syntrophin-dependent pool of AQP4 in astroglial end-feet confers bidirectional water flow between blood and brain

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PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)

Review Biochemistry & Molecular Biology

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CURRENT OPINION IN STRUCTURAL BIOLOGY (2002)

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Syntrophin-dependent expression and localization of Aquaporin-4 water channel protein

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PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)

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Regional differences in mechanisms of cerebral circulatory response to neuronal activation

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AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY (2001)

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Structural determinants of water permeation through aquaporin-1

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NATURE (2000)

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Cyclooxygenase-2 contributes to functional hyperemia in whisker-barrel cortex

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