4.8 Article

Similarities and Differences in the Acute-Phase Response to SARS-CoV-2 in Rhesus Macaques and African Green Monkeys

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Hematology

A meta-analysis of SARS-CoV-2 patients identifies the combinatorial significance of D-dimer, C-reactive protein, lymphocyte, and neutrophil values as a predictor of disease severity

Kunwar Singh et al.

Summary: This study aimed to evaluate the significance of multiple laboratory blood values in patients with SARS-CoV-2 and develop COVID-19 predictive equations. The results showed that the generated predictive equations exhibited high specificity, sensitivity, positive predictive values, and negative predictive values in adult and pediatric populations.

INTERNATIONAL JOURNAL OF LABORATORY HEMATOLOGY (2021)

Article Biochemistry & Molecular Biology

Baricitinib treatment resolves lower-airway macrophage inflammation and neutrophil recruitment in SARS-CoV-2-infected rhesus macaques

Timothy N. Hoang et al.

Summary: The study found that in a rhesus macaque model of SARS-CoV-2 infection, baricitinib did not reduce viral shedding, but did decrease inflammation and suppress the production of cytokines and chemokines, suggesting its potential as an effective treatment for COVID-19 inflammation.
Article Immunology

Establishment of an African green monkey model for COVID-19 and protection against re-infection

Courtney Woolsey et al.

Summary: African green monkeys infected with SARS-CoV-2 exhibit symptoms closely resembling those in humans, making them a valuable model for studying COVID-19 pathogenesis and testing medical interventions.

NATURE IMMUNOLOGY (2021)

Article Multidisciplinary Sciences

SARS-CoV-2 induces robust germinal center CD4 T follicular helper cell responses in rhesus macaques

Yashavanth Shaan Lakshmanappa et al.

Summary: Induction of CD4 T follicular helper (Tfh) cells is crucial for antibody responses to viral infections, as shown in a rhesus macaque model of mild COVID-19 where SARS-CoV-2 infection resulted in transient accumulation of proliferating Tfh cells with a Th1 profile in peripheral blood and the generation of germinal center Tfh cells specific for viral proteins.

NATURE COMMUNICATIONS (2021)

Article Microbiology

Responses to acute infection with SARS-CoV-2 in the lungs of rhesus macaques, baboons and marmosets

Dhiraj Kumar Singh et al.

Summary: Non-human primate models, particularly macaques and baboons, demonstrate acute respiratory distress and immune responses similar to COVID-19 progression in humans, making them valuable for testing vaccines and therapies. Age appears to affect viral shedding, lung inflammation, and immune response in these animal models.

NATURE MICROBIOLOGY (2021)

Article Pathology

Acute Respiratory Distress in Aged, SARS-CoV-2-Infected African Green Monkeys but Not Rhesus Macaques

Robert V. Blair et al.

Summary: This study reported two cases of ARDS in AGMs infected with SARS-CoV-2, as well as a comparatively mild COVID-19 phenotype in two surviving AGMs and four infected RMs. The results suggest that aged AGMs may be useful for modeling severe disease manifestations related to COVID-19.

AMERICAN JOURNAL OF PATHOLOGY (2021)

Article Virology

Neutralizing antibody-dependent and -independent immune responses against SARS-CoV-2 in cynomolgus macaques

Hirohito Ishigaki et al.

Summary: Cynomolgus macaques were used to establish an animal model of COVID-19 to develop vaccines and antiviral drugs, showing similar symptoms to human patients. The study found that both neutralizing antibodies and cellular immunity play important roles in eliminating SARS-CoV-2.

VIROLOGY (2021)

Article Medicine, General & Internal

Clinical Characteristics of Coronavirus Disease 2019 in China

W. Guan et al.

NEW ENGLAND JOURNAL OF MEDICINE (2020)

Article Biochemistry & Molecular Biology

Imbalanced Host Response to SARS-CoV-2 Drives Development of COVID-19

Daniel Blanco-Melo et al.

Review Immunology

Targeting potential drivers of COVID-19: Neutrophil extracellular traps

Betsy J. Barnes et al.

JOURNAL OF EXPERIMENTAL MEDICINE (2020)

Article Multidisciplinary Sciences

DNA vaccine protection against SARS-CoV-2 in rhesus macaques

Jingyou Yu et al.

SCIENCE (2020)

Article Immunology

TH17 responses in cytokine storm of COVID-19: An emerging target of JAK2 inhibitor Fedratinib

Dandan Wu et al.

JOURNAL OF MICROBIOLOGY IMMUNOLOGY AND INFECTION (2020)

Article Multidisciplinary Sciences

Virological assessment of hospitalized patients with COVID-2019

Roman Woelfel et al.

NATURE (2020)

Article Medicine, General & Internal

Mild or Moderate Covid-19

Rajesh T. Gandhi et al.

NEW ENGLAND JOURNAL OF MEDICINE (2020)

Article Biochemistry & Molecular Biology

Severe COVID-19 Is Marked by a Dysregulated Myeloid Cell Compartment

Jonas Schulte-Schrepping et al.

Article Medicine, Research & Experimental

COVID-19 severity associates with pulmonary redistribution of CD1c+ DCs and inflammatory transitional and nonclassical monocytes

Ildefonso Sanchez-Cerrillo et al.

JOURNAL OF CLINICAL INVESTIGATION (2020)

Article Multidisciplinary Sciences

Systems biological assessment of immunity to mild versus severe COVID-19 infection in humans

Prabhu S. Arunachalam et al.

SCIENCE (2020)

Article Multidisciplinary Sciences

Inborn errors of type I IFN immunity in patients with life-threatening COVID-19

Qian Zhang et al.

SCIENCE (2020)

Article Immunology

Continuous tracking of COVID-19 patients' immune status

Jingjing Guan et al.

INTERNATIONAL IMMUNOPHARMACOLOGY (2020)

Article Multidisciplinary Sciences

Cellular events of acute, resolving or progressive COVID-19 in SARS-CoV-2 infected non-human primates

M. D. Fahlberg et al.

NATURE COMMUNICATIONS (2020)

Article Medicine, Research & Experimental

High-fat diet exacerbates SIV pathogenesis and accelerates disease progression

Tianyu He et al.

JOURNAL OF CLINICAL INVESTIGATION (2019)

Article Microbiology

MERS-CoV Accessory ORFs Play Key Role for Infection and Pathogenesis

Vineet D. Menachery et al.

Article Virology

Animal models for SARS and MERS coronaviruses

Lisa M. Gretebeck et al.

CURRENT OPINION IN VIROLOGY (2015)

Article Biotechnology & Applied Microbiology

Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2

Michael I. Love et al.

GENOME BIOLOGY (2014)

Article Biochemical Research Methods

STAR: ultrafast universal RNA-seq aligner

Alexander Dobin et al.

BIOINFORMATICS (2013)

Article Multidisciplinary Sciences

Middle East respiratory syndrome coronavirus (MERS-CoV) causes transient lower respiratory tract infection in rhesus macaques

Emmie de Wit et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)

Article Biotechnology & Applied Microbiology

Characterization of a model of lethal dengue virus 2 infection in C57BL/6 mice deficient in the alpha/beta interferon receptor

Susana Orozco et al.

JOURNAL OF GENERAL VIROLOGY (2012)

Article Virology

Induction and function of type I and III interferon in response to viral infection

David E. Levy et al.

CURRENT OPINION IN VIROLOGY (2011)

Review Cell Biology

Neutrophil-derived azurocidin alarms the immune system

Oliver Soehnlein et al.

JOURNAL OF LEUKOCYTE BIOLOGY (2009)

Article Biochemical Research Methods

WGCNA: an R package for weighted correlation network analysis

Peter Langfelder et al.

BMC BIOINFORMATICS (2008)

Review Biotechnology & Applied Microbiology

The multifunctional NS1 protein of influenza A viruses

Benjamin G. Hale et al.

JOURNAL OF GENERAL VIROLOGY (2008)

Article Virology

Protective role of beta interferon in host defense against influenza A virus

Iris Koerner et al.

JOURNAL OF VIROLOGY (2007)

Article Multidisciplinary Sciences

IRF-7 is the master regulator of type-I interferon-dependent immune responses

K Honda et al.

NATURE (2005)

Article Biochemistry & Molecular Biology

Pegylated interferon-α protects type 1 pneumocytes against SARS coronavirus infection in macaques

BL Haagmans et al.

NATURE MEDICINE (2004)