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New challenges in the use of nanomedicine in cancer therapy

期刊

BIOENGINEERED
卷 13, 期 1, 页码 759-773

出版社

TAYLOR & FRANCIS INC
DOI: 10.1080/21655979.2021.2012907

关键词

Nanomedicine; active targeting; passive targeting; nanomaterials; nanoshells

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Nanomedicines have been applied as alternative treatments for anticancer agents, utilizing their small size to achieve specific site targeting and reduce toxic side effects. They also offer cost savings by requiring minute amounts of drugs. Nanotechnology has been effectively utilized in the preparation of these drugs, and large nanomaterials have been used to develop novel cancer cures.
Nanomedicines are applied as alternative treatments for anticancer agents. For the treatment of cancer, due to the small size in nanometers (nm), specific site targeting can be achieved with the use of nanomedicines, increasing their bioavailability and conferring fewer toxic side effects. Additionally, the use of minute amounts of drugs can lead to cost savings. In addition, nanotechnology is effectively applied in the preparation of such drugs as they are in nm sizes, considered one of the earliest cutoff values for the production of products utilized in nanotechnology. Early concepts described gold nanoshells as one of the successful therapies for cancer and associated diseases where the benefits of nanomedicine include effective active or passive targeting. Common medicines are degraded at a higher rate, whereas the degradation of macromolecules is time-consuming. All of the discussed properties are responsible for executing the physiological behaviors occurring at the following scale, depending on the geometry. Finally, large nanomaterials based on organic, lipid, inorganic, protein, and synthetic polymers have also been utilized to develop novel cancer cures.

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