期刊
APPLIED SCIENCES-BASEL
卷 11, 期 23, 页码 -出版社
MDPI
DOI: 10.3390/app112311261
关键词
anticancer; seaweeds; polysaccharide; polyphenol; carotenoids; terpenoids
类别
资金
- National Research Foundation of Korea [NRF-2019K1A3A1A82113697]
- KIST Institutional Program [2Z06603, 2Z06481]
- National Research Council of Science and Technology (NST) [CRC-15-04-KIST]
- National Research Foundation of Korea [2019K1A3A1A82113697] Funding Source: Korea Institute of Science & Technology Information (KISTI), National Science & Technology Information Service (NTIS)
Seaweeds are rich in bioactive compounds that exhibit cytotoxicity against cancer cells and have the potential to induce apoptosis and inhibit tumor growth.
Cancer remains a major life-threatening disease worldwide. The development of anticancer drugs using natural products obtained from marine organisms has been proposed as an alternative approach. Seaweeds are the mainstay of marine ecosystems; therefore, they are highly enriched with diverse bioactive compounds. In the past decade, a vast number of natural compounds, such as polysaccharides, polyphenols, carotenoids, and terpenoids, have been isolated from seaweeds. Seaweeds have bioactive compounds that show cytotoxicity in various cancer cell lines. These compounds prevent tumor growth by inducing apoptotic cell death and arrest growth by interfering with different kinases and cell cycle pathways. This review discussed the anticancer properties of various bioactive compounds isolated from different types of seaweeds and their therapeutic potential against cancers.
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