期刊
ADVANCED SCIENCE
卷 9, 期 8, 页码 -出版社
WILEY
DOI: 10.1002/advs.202104372
关键词
human macrophages; IFN gamma Iota IGF2BP2; LPS; macrophage polarization; mouse macrophages; species difference
资金
- Deutsche Forschungsgemeinschaft [KI702]
This study provides initial insights into the regulation and role of IMP2 in macrophage activation. Differences in the regulation of IMP2 between inflammatory and anti-inflammatory macrophages were observed.
Recently, first insights into the regulation and the role of the RNA-binding protein IMP2 in macrophage activation have been published by Wang et al. This study addresses differences in the regulation of IMP2 between the human and murine system. While the expression of IMP2 in anti-inflammatory macrophages is synchronous in mice and men, IMP2 expression is regulated differently in inflammatory macrophages.
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