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NATURE COMMUNICATIONS (2012)
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Targeting the brain with PEG-PLGA nanoparticles modified with phage-displayed peptides
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EXPERT OPINION ON DRUG DELIVERY (2011)
Analyses of nanoformulated antiretroviral drug charge, size, shape and content for uptake, drug release and antiviral activities in human monocyte-derived macrophages
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Targeting the insulin receptor: nanoparticles for drug delivery across the blood-brain barrier (BBB)
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Quantitative targeted absolute proteomics of human blood-brain barrier transporters and receptors
Yasuo Uchida et al.
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Development of a three-dimensional, all-human in vitro model of the blood-brain barrier using mono-, co-, and tri-cultivation Transwell models
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In Vitro Primary Human and Animal Cell-Based Blood-Brain Barrier Models as a Screening Tool in Drug Discovery
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Surface Characteristics of Nanoparticles Determine Their Intracellular Fate in and Processing by Human Blood-Brain Barrier Endothelial Cells In Vitro
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REVIEWS IN THE NEUROSCIENCES (2011)
Blood-Brain Barrier Pathophysiology in Traumatic Brain Injury
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TRANSLATIONAL STROKE RESEARCH (2011)
Evaluation of various PAMPA models to identify the most discriminating method for the prediction of BBB permeability
Jurgen Mensch et al.
EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS (2010)
In Vitro Blood-Brain Barrier Models - Latest Advances and Therapeutic Applications in a Chronological Perspective
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MINI-REVIEWS IN MEDICINAL CHEMISTRY (2010)
Characterization of endocytosis of transferrin-coated PLGA nanoparticles by the blood-brain barrier
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In Vivo, In Vitro and In Silico Methods for Small Molecule Transfer Across the BBB
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NEUROCHEMISTRY INTERNATIONAL (2009)
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BIOMATERIALS (2008)
In silico prediction of brain and CSF permeation of small molecules using PLS regression models
Stefanie Bendels et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2008)
The human brain endothelial cell line hCMEC/D3 as a human blood-brain barrier model for drug transport studies
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Modelling of the blood-brain barrier in drug discovery and development
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NATURE REVIEWS DRUG DISCOVERY (2007)
Translocation of poly(ethylene glycol-co-hexadecyl)cyanoacrylate nanoparticles into rat brain endothelial cells:: Role of apolipoproteins in receptor-mediated endocytosis
Hyun R. Kim et al.
BIOMACROMOLECULES (2007)
Exogenous expression of claudin-5 induces barrier properties in cultured rat brain capillary endothelial cells
Sumio Ohtsuki et al.
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Toxicity of cationic lipids and cationic polymers in gene delivery
Hongtao Lv et al.
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Covalent linkage of apolipoprotein E to albumin nanoparticles strongly enhances drug transport into the brain
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In silico predictions of blood-brain barrier penetration: Considerations to keep in mind
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Double-coated poly (butylcynanoacrylate) nanoparticulate delivery systems for brain targeting of dalargin via oral administration
D Das et al.
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Cationic albumin conjugated pegylated nanoparticle with its transcytosis ability and little toxicity against blood-brain barrier
W Lu et al.
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Permeability studies on in vitro blood-brain barrier models: Physiology, pathology, and pharmacology
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Computational models to predict blood-brain barrier permeation and CNS activity
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Characterisation of the brain multidrug resistance protein (BMDP/ABCG2/BCRP) expressed at the blood-brain barrier
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BRAIN RESEARCH (2003)
Assessment of sensorimotor and cognitive deficits induced by a moderate traumatic injury in the right parietal cortex of the rat
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NEUROBIOLOGY OF DISEASE (2001)
Progress and limitations in the use of in vitro cell cultures to serve as a permeability screen for the blood-brain barrier
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