Invited review: Remediation strategies for mycotoxin control in feed

Mycotoxins are secondary metabolites of different species of fungi. Aflatoxin B-1 (AFB(1)), deoxynivalenol (DON), zearalenone (ZEN) and fumonisin B-1 (FB1) are the main mycotoxins contaminating animal feedstuffs. These mycotoxins can primarily induce hepatotoxicity, immunotoxicity, neurotoxicity and nephrotoxicity, consequently cause adverse effects on the health and performance of animals. Therefore, physical, chemical, biological and nutritional regulation approaches have been developed as primary strategies for the decontamination and detoxification of these mycotoxins in the feed industry. Meanwhile, each of these techniques has its drawbacks, including inefficient, costly, or impractically applied on large scale. This review summarized the advantages and disadvantages of the different remediation strategies, as well as updates of the research progress of these strategies for AFB(1), DON, ZEN and FB1 control in the feed industry.

Automated summary

Mycotoxins, secondary metabolites of fungi, are a major concern in animal feed with adverse effects on animal health. Various strategies including physical, chemical, biological, and nutritional approaches have been developed for the decontamination and detoxification of mycotoxins. However, each strategy has its limitations. This review provides an overview of the advantages and disadvantages of different remediation strategies and updates on the research progress in controlling mycotoxins in the feed industry.