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Dengue Virus Capsid Protein Binding to Hepatic Lipid Droplets (LD) Is Potassium Ion Dependent and Is Mediated by LD Surface Proteins
Filomena A. Carvalho et al.
JOURNAL OF VIROLOGY (2012)
Identification of the Niemann-Pick C1-like 1 cholesterol absorption receptor as a new hepatitis C virus entry factor
Bruno Sainz et al.
NATURE MEDICINE (2012)
Early Dengue Virus Protein Synthesis Induces Extensive Rearrangement of the Endoplasmic Reticulum Independent of the UPR and SREBP-2 Pathway
Jose Pena et al.
PLOS ONE (2012)
Dengue Virus Infection Perturbs Lipid Homeostasis in Infected Mosquito Cells
Rushika Perera et al.
PLOS PATHOGENS (2012)
mTOR Complex 1 Regulates Lipin 1 Localization to Control the SREBP Pathway
Timothy R. Peterson et al.
CELL (2011)
Effects of Hypolipidemic Agent Nordihydroguaiaretic Acid on Lipid Droplets and Hepatitis C Virus
Gulam H. Syed et al.
HEPATOLOGY (2011)
Statins Reduce Dengue Virus Production via Decreased Virion Assembly
Marlen Martinez-Gutierrez et al.
INTERVIROLOGY (2011)
Biochemical and Morphological Properties of Hepatitis C Virus Particles and Determination of Their Lipidome
Andreas Merz et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
Flavivirus NS4A-induced Autophagy Protects Cells against Death and Enhances Virus Replication
Jeffrey E. McLean et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
Ebola virus entry requires the cholesterol transporter Niemann-Pick C1
Jan E. Carette et al.
NATURE (2011)
AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1
Joungmok Kim et al.
NATURE CELL BIOLOGY (2011)
Molecular mechanisms involved in the early steps of flavivirus cell entry
Baerbel Kaufmann et al.
MICROBES AND INFECTION (2011)
West Nile Virus Replication Requires Fatty Acid Synthesis but Is Independent on Phosphatidylinositol-4-Phosphate Lipids
Miguel A. Martin-Acebes et al.
PLOS ONE (2011)
Host Defense against Viral Infection Involves Interferon Mediated Down-Regulation of Sterol Biosynthesis
Mathieu Blanc et al.
PLOS BIOLOGY (2011)
The Epidemiology of Dengue in the Americas Over the Last Three Decades: A Worrisome Reality
Jose Luis San Martin et al.
AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE (2010)
Simvastatin potentiates the anti-hepatitis B virus activity of FDA-approved nucleoside analogue inhibitors in vitro
Ted Bader et al.
ANTIVIRAL RESEARCH (2010)
Dengue Virus-Induced Autophagy Regulates Lipid Metabolism
Nicholas S. Heaton et al.
CELL HOST & MICROBE (2010)
Role of KLF15 in Regulation of Hepatic Gluconeogenesis and Metformin Action
Mototsugu Takashima et al.
DIABETES (2010)
New Translational Research on Novel Drugs for Hepatitis C Virus 1b Infection by Using a Replicon System and Human Induced Pluripotent Stem Cells
Hisashi Moriguchi et al.
HEPATOLOGY (2010)
Characterization of the functional requirements of West Nile virus membrane fusion
Bastiaan Moesker et al.
JOURNAL OF GENERAL VIROLOGY (2010)
Antibody-dependent enhancement of dengue virus infection in U937 cells requires cholesterol-rich membrane microdomains
Henry Puerta-Guardo et al.
JOURNAL OF GENERAL VIROLOGY (2010)
Involvement of Ceramide in the Propagation of Japanese Encephalitis Virus
Hideki Tani et al.
JOURNAL OF VIROLOGY (2010)
Activation of a Metabolic Gene Regulatory Network Downstream of mTOR Complex 1
Katrin Duevel et al.
MOLECULAR CELL (2010)
Bifurcation of insulin signaling pathway in rat liver: mTORC1 required for stimulation of lipogenesis, but not inhibition of gluconeogenesis
Shijie Li et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
Enhanced hepatitis C virus genome replication and lipid accumulation mediated by inhibition of AMP-activated protein kinase
Jamel Mankouri et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
Dengue virus nonstructural protein 3 redistributes fatty acid synthase to sites of viral replication and increases cellular fatty acid synthesis
Nicholas S. Heaton et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
Roles of Small GTPase Rac1 in the Regulation of Actin Cytoskeleton during Dengue Virus Infection
Jia-Li Wang et al.
PLOS NEGLECTED TROPICAL DISEASES (2010)
Dengue Virus Ensures Its Fusion in Late Endosomes Using Compartment-Specific Lipids
Elena Zaitseva et al.
PLOS PATHOGENS (2010)
Membrane microdomains: Role of ceramides in the maintenance of their structure and functions
Galya Staneva et al.
BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES (2009)
Cholesterol-induced fluid membrane domains: A compendium of lipid-raft ternary phase diagrams
Derek Marsh
BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES (2009)
Composition and Three-Dimensional Architecture of the Dengue Virus Replication and Assembly Sites
Sonja Welsch et al.
CELL HOST & MICROBE (2009)
Alternative infectious entry pathways for dengue virus serotypes into mammalian cells
Eliana G. Acosta et al.
CELLULAR MICROBIOLOGY (2009)
Evaluation of the efficacy and safety of a statin/caffeine combination against H5N1, H3N2 and H1N1 virus infection in BALB/c mice
Zeyu Liu et al.
EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES (2009)
Ezetimibe/simvastatin
Fabrizio Montecucco et al.
EXPERT OPINION ON DRUG SAFETY (2009)
Statins Potentiate the In Vitro Anti-Hepatitis C Virus Activity of Selective Hepatitis C Virus Inhibitors and Delay or Prevent Resistance Development
Leen Delang et al.
HEPATOLOGY (2009)
Co-localization of constituents of the dengue virus translation and replication machinery with amphisomes
Mingkwan Panyasrivanit et al.
JOURNAL OF GENERAL VIROLOGY (2009)
Cross-talk between Rac1 and Cdc42 GTPases regulates formation of filopodia required for dengue virus type-2 entry into HMEC-1 cells
Horacio Zamudio-Meza et al.
JOURNAL OF GENERAL VIROLOGY (2009)
A role for autophagolysosomes in dengue virus 3 production in HepG2 cells
Atefeh Khakpoor et al.
JOURNAL OF GENERAL VIROLOGY (2009)
AMPK in the brain: its roles in energy balance and neuroprotection
Gabriele V. Ronnett et al.
JOURNAL OF NEUROCHEMISTRY (2009)
Autophagy regulates lipid metabolism
Rajat Singh et al.
NATURE (2009)
Influenza Morbidity and Mortality in Elderly Patients Receiving Statins: A Cohort Study
Jeffrey C. Kwong et al.
PLOS ONE (2009)
Antidiabetic drug metformin (GlucophageR) increases biogenesis of Alzheimer's amyloid peptides via up-regulating BACE1 transcription
Yaomin Chen et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
Cholesterol biosynthesis modulation regulates dengue viral replication
Christopher Rothwell et al.
VIROLOGY (2009)
Do statins reduce hepatitis C RNA titers during routine clinical use?
Kimberly A. Forde et al.
WORLD JOURNAL OF GASTROENTEROLOGY (2009)
Dengue Virus Capsid Protein Usurps Lipid Droplets for Viral Particle Formation
Marcelo M. Samsa et al.
PLOS PATHOGENS (2009)
Fluvastatin inhibits hepatitis C replication in humans
Ted Bader et al.
AMERICAN JOURNAL OF GASTROENTEROLOGY (2008)
Interplay of unsaturated phospholipids and cholesterol in membranes:: Effect of the double-bond position
Hector Martinez-Seara et al.
BIOPHYSICAL JOURNAL (2008)
SREBP activity is regulated by mTORC1 and contributes to Akt-dependent cell growth
Thomas Porstmann et al.
CELL METABOLISM (2008)
The cholesterol absorption inhibitor ezetimibe acts by blocking the sterol-induced internalization of NPC1L1
Liang Ge et al.
CELL METABOLISM (2008)
Autophagy and antiviral immunity
Heung Kyu Lee et al.
CURRENT OPINION IN IMMUNOLOGY (2008)
Targeting the PI3K/Akt/mTOR pathway: Effective combinations and clinical considerations
Jaclyn LoPiccolo et al.
DRUG RESISTANCE UPDATES (2008)
Critical role of virion-associated cholesterol and sphingolipid in hepatitis C virus infection
Hideki Aizaki et al.
JOURNAL OF VIROLOGY (2008)
West nile virus entry requires cholesterol-rich membrane microdomains and is independent of αvβ3 integrin
Guruprasad R. Medigeshi et al.
JOURNAL OF VIROLOGY (2008)
Differential cholesterol binding by class II fusion proteins determines membrane fusion properties
M. Umashankar et al.
JOURNAL OF VIROLOGY (2008)
Cholesterol effectively blocks entry of flavivirus
Chyan-Jang Lee et al.
JOURNAL OF VIROLOGY (2008)
Opinion -: Architects of assembly:: roles of Flaviviridae non-structural proteins in virion morphogenesis
Catherine L. Murray et al.
NATURE REVIEWS MICROBIOLOGY (2008)
Ceramide triggers budding of exosome vesicles into multivesicular Endosomes
Katarina Trajkovic et al.
SCIENCE (2008)
Endocytic pathway followed by dengue virus to infect the mosquito cell line C6/36 HT
Clemente Mosso et al.
VIROLOGY (2008)
Autophagic machinery activated by dengue virus enhances virus replication
Ying-Ray Lee et al.
VIROLOGY (2008)
Dissecting the Cell Entry Pathway of Dengue Virus by Single-Particle Tracking in Living Cells
Hilde M. van der Schaar et al.
PLOS PATHOGENS (2008)
Effect of genetic variation in the organic cation transporter 1, OCT1, on metformin pharmacokinetics
Y. Shu et al.
CLINICAL PHARMACOLOGY & THERAPEUTICS (2008)
Cholesterol manipulation by west nile virus perturbs the cellular immune response
Jason M. Mackenzie et al.
CELL HOST & MICROBE (2007)
The lipid droplet is an important organelle for hepatitis C virus production
Yusuke Miyanari et al.
NATURE CELL BIOLOGY (2007)
The non-structural protein 4A of dengue virus is an integral membrane protein inducing membrane alterations in a 2K-regulated manner
Sven Miller et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
Acetyl-coenzyme A carboxylases: Versatile targets for drug discovery
Liang Tong et al.
JOURNAL OF CELLULAR BIOCHEMISTRY (2006)
Lipid-lowering drugs
K. Pahan
CELLULAR AND MOLECULAR LIFE SCIENCES (2006)
The HIV lipidome:: A raft with an unusual composition
B Brügger et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
Flavivirus activates phosphatidylinositol 3-kinase signaling to block caspase-dependent apoptotic cell death at the early stage of virus infection
CJ Lee et al.
JOURNAL OF VIROLOGY (2005)
The target of ezetimibe is Niemann-Pick Cl-Like 1 (NPC1L1)
M Garcia-Calvo et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
Pharmacological inhibition of AMP-activated protein kinase provides neuroprotection in stroke
LD McCullough et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Role of curvature and phase transition in lipid sorting and fission of membrane tubules
A Roux et al.
EMBO JOURNAL (2005)
Heat shock protein 90 and heat shock protein 70 are components of dengue virus receptor complex in human cells
JRD Valle et al.
JOURNAL OF VIROLOGY (2005)
Hydroxymethyl-glutaryl coenzyme A reductase inhibition limits cytomegalovirus infection in human endothelial cells
L Potena et al.
CIRCULATION (2004)
Statins inhibit HIV-1 infection by down-regulating Rho activity
G del Real et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2004)
Effect of membrane curvature-modifying lipids on membrane fusion by tick-borne encephalitis virus
K Stiasny et al.
JOURNAL OF VIROLOGY (2004)
Effects of HMG-CoA reductase inhibition on hepatic expression of key cholesterol-regulatory enzymes and receptors in nephrotic syndrome
ND Vaziri et al.
AMERICAN JOURNAL OF NEPHROLOGY (2004)
Lipid rafts and HIV pathogenesis: Virion-associated cholesterol is required for fusion and infection of susceptible cells
ZH Liao et al.
AIDS RESEARCH AND HUMAN RETROVIRUSES (2003)
Involvement of lipids in different steps of the flavivirus fusion mechanism
K Stiasny et al.
JOURNAL OF VIROLOGY (2003)
Role for influenza virus envelope cholesterol in virus entry and infection
XJ Sun et al.
JOURNAL OF VIROLOGY (2003)
The surface of lipid droplets is a phospholipid monolayer with a unique fatty acid composition
K Tauchi-Sato et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Role of AMP-activated protein kinase in mechanism of metformin action
GC Zhou et al.
JOURNAL OF CLINICAL INVESTIGATION (2001)
Antiviral activity of lovastatin against respiratory syncytial virus in vivo and in vitro
TL Gower et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2001)
Membrane raft microdomains mediate lateral assemblies required for HIV-1 infection
S Mañes et al.
EMBO REPORTS (2000)
Vectorial budding of vesicles by asymmetrical enzymatic formation of ceramide in giant liposomes
JM Holopainen et al.
BIOPHYSICAL JOURNAL (2000)
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