4.7 Article

Short-Term Efficacy and Safety Outcomes of Brolucizumab in the Real-Life Clinical Practice

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Ophthalmology

Short-term real-world outcomes following intravitreal brolucizumab for neovascular AMD: SHIFT study

Louisa Maria Bulirsch et al.

Summary: Switch to brolucizumab may be a viable treatment option for nAMD patients who are poorly responsive to other anti-VEGF agents, as indicated by the SHIFT study results. However, further long-term analyses are necessary to assess the efficacy and safety of brolucizumab in a routine clinical setting.

BRITISH JOURNAL OF OPHTHALMOLOGY (2022)

Editorial Material Ophthalmology

Brolucizumab-early real-world experience: BREW study

Ashish Sharma et al.

Article Ophthalmology

Early Experience With Brolucizumab Treatment of Neovascular Age-Related Macular Degeneration

Ana Bety Enriquez et al.

Summary: In this analysis of brolucizumab intravitreal injection for neovascular age-related macular degeneration, visual acuity remained stable with a reduction in central subfield thickness. Intraocular inflammation events ranged from mild and self-limited to severe occlusive retinal vasculitis in one eye.

JAMA OPHTHALMOLOGY (2021)

Letter Ophthalmology

Brolucizumab-related intraocular inflammation in Japanese patients with age-related macular degeneration: a short-term multicenter study

Ichiro Maruko et al.

GRAEFES ARCHIVE FOR CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY (2021)

Review Ophthalmology

Risk of Inflammation, Retinal Vasculitis, and Retinal Occlusion-Related Events with Brolucizumab Post Hoc Review of HAWK and HARRIER

Jordi Mones et al.

Summary: The analysis of intraocular inflammation cases after brolucizumab injection identified signs of retinal vasculitis with or without retinal vascular occlusion and an associated risk of visual acuity loss.

OPHTHALMOLOGY (2021)

Article Medicine, General & Internal

Switching to Brolucizumab in Neovascular Age-Related Macular Degeneration Incompletely Responsive to Ranibizumab or Aflibercept: Real-Life 6 Month Outcomes

Christof Haensli et al.

Summary: The study aimed to evaluate the effect of switching treatment to brolucizumab in eyes with neovascular age-related macular degeneration with treatment intervals of <= 6 weeks. Results showed improvement in visual performance and longer treatment intervals over 6 months, indicating the potential of brolucizumab to reduce treatment burden in nAMD, despite encountering two cases of intraocular inflammation.

JOURNAL OF CLINICAL MEDICINE (2021)

Article Ophthalmology

Expert Opinion on Management of Intraocular Inflammation, Retinal Vasculitis, and Vascular Occlusion after Brolucizumab Treatment

Caroline R. Baumal et al.

Summary: This study presents clinical presentations and management recommendations for ocular inflammatory events in neovascular age-related macular degeneration (nAMD) patients treated with brolucizumab. Recommendations include thorough ocular examinations and imaging modalities, prompt cessation of treatment and intensive therapy if diagnosed with inflammatory events, and consideration of individualized locally available standard of care based on clinical outcomes.

OPHTHALMOLOGY RETINA (2021)

Editorial Material Ophthalmology

Brolucizumab and fluid in neovascular age-related macular degeneration (n-AMD)

Ashish Sharma et al.

Article Ophthalmology

Brolucizumab and immunogenicity

Ashish Sharma et al.

Editorial Material Ophthalmology

Brolucizumab-key learnings from HAWK and HARRIER

Ashish Sharma et al.

Editorial Material Ophthalmology

Brolucizumab: the road ahead

Ashish Sharma et al.

BRITISH JOURNAL OF OPHTHALMOLOGY (2020)

Article Ophthalmology

HAWK and HARRIER

Pravin U. Dugel et al.

OPHTHALMOLOGY (2020)

Article Ophthalmology

Reply to Comment on: Is this a 737 Max Moment for Brolucizumab?

Philip J. Rosenfeld et al.

AMERICAN JOURNAL OF OPHTHALMOLOGY (2020)

Review Biochemistry & Molecular Biology

Neovascular Age-Related Macular Degeneration: Therapeutic Management and New-Upcoming Approaches

Federico Ricci et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2020)

Article Medicine, General & Internal

Case Series on Initial Responses to Intravitreal Brolucizumab in Patients with Recalcitrant Chronic Wet Age-Related Macular Degeneration

Jaycob Avaylon et al.

INTERNATIONAL MEDICAL CASE REPORTS JOURNAL (2020)

Review Medicine, General & Internal

Anti-vascular endothelial growth factor for neovascular age-related macular degeneration

Sharon D. Solomon et al.

COCHRANE DATABASE OF SYSTEMATIC REVIEWS (2019)

Article Ophthalmology

Geo-Epidemiology of Age-Related Macular Degeneration: New Clues Into the Pathogenesis

Michele Reibaldi et al.

AMERICAN JOURNAL OF OPHTHALMOLOGY (2016)

Editorial Material Ophthalmology

Standardization of uveitis nomenclature for reporting clinical data. Results of the First International Workshop

DA Jabs et al.

AMERICAN JOURNAL OF OPHTHALMOLOGY (2005)