4.7 Review

New Insights Into the Effects of Individual Chinese Herbal Medicines on Chronic Kidney Disease

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Review Pharmacology & Pharmacy

Mechanisms and Efficacy of Chinese Herbal Medicines in Chronic Kidney Disease

Mingming Zhao et al.

Summary: Through reviewing publications in peer-reviewed English-language journals, it is found that Chinese herbal medicines (CHMs) have anti-inflammatory, antioxidative, anti-apoptotic, autophagy-mediated, and antifibrotic effects in the treatment of chronic kidney disease (CKD). Some studies suggest that CHMs as an adjuvant therapy may benefit CKD patients. However, issues such as unknown active ingredients, low quality and small sample sizes in clinical trials limit the development and safety of CHMs. Further research and well-conducted randomized controlled trials (RCTs) are urgently needed to evaluate the efficacy and safety of CHMs in CKD treatment.

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