期刊
FRONTIERS IN PHARMACOLOGY
卷 12, 期 -, 页码 -出版社
FRONTIERS MEDIA SA
DOI: 10.3389/fphar.2021.790784
关键词
chemotherapy; nausea; vomiting; traditional Chinese medicine; review
资金
- National Natural Science Foundation of China [82174143, 81673779]
- Key Subject Research Projects of Guangdong Province in China [2019-GDXK-0011]
Chemotherapy-induced nausea and vomiting significantly affects the quality of life in cancer patients. Traditional Chinese medicine has been recognized for its potential in treating these side effects, leading to increased research attention.
Chemotherapy-induced nausea and vomiting (CINV), a common side effect in antineoplastic treatment, dramatically decreases the quality of life as well as the compliance of cancer patients. Although numerous antiemetic agents have been used for CINV treatment, its adverse reactions as well as its inadequate control toward delayed emesis still limit its clinical usage. Traditional Chinese medicine (TCM), with more than 3,000 years of practical history in Asia, has been successfully applied to mitigate chemotherapy-induced side effects. Growing attention is drawn to the antiemetic effect of TCM against CINV due to its promising therapeutic property and higher safety recently. In this review, we summarize the classic antiemetic TCM-based treatment and its mechanisms, so as to provide a theoretical basis for further investigations of TCM against CINV in the future.
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