4.7 Article

Astragalus mongholicus Bunge Water Extract Exhibits Anti-inflammatory Effects in Human Neutrophils and Alleviates Imiquimod-Induced Psoriasis-Like Skin Inflammation in Mice

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Biochemical Research Methods

Quantification by LC-MS/MS of astragaloside IV and isoflavones inAstragali radixcan be more accurate by using standard addition

Bijay Kafle et al.

Summary: Astragali radix, a traditional Chinese medical herb, contains bioactive components such as astragalosides that require accurate measurement. The study found that LC-MS/MS quantification using standard addition is a powerful approach for measuring phytochemicals, overcoming ion suppression effects caused by sample matrix.

PHYTOCHEMICAL ANALYSIS (2021)

Article Immunology

Astragaloside IV promotes microglia/macrophages M2 polarization and enhances neurogenesis and angiogenesis through PPARγ pathway after cerebral ischemia/reperfusion injury in rats

Lin Li et al.

Summary: The study demonstrated that AS-IV can improve long-term brain injury after cerebral ischemia/reperfusion by promoting the polarization of microglia/macrophages and increasing the expression of PPAR-γ, leading to enhanced neurogenesis and angiogenesis.

INTERNATIONAL IMMUNOPHARMACOLOGY (2021)

Article Pharmacology & Pharmacy

Astragali Radix Isoflavones Synergistically Alleviate Cerebral Ischemia and Reperfusion Injury Via Activating Estrogen Receptor-PI3K-Akt Signaling Pathway

Yong Gu et al.

Summary: In this study, it was found that isoflavones from Astragali Radix can synergistically alleviate cerebral ischemia-reperfusion injury by activating the ER-PI3K-Akt signaling pathway, demonstrating their neuroprotective effects against neural death induced by ischemia-reperfusion.

FRONTIERS IN PHARMACOLOGY (2021)

Article Pediatrics

Dysregulation of Ki-67 Expression in T Cells of Children with Autism Spectrum Disorder

Khaled Alhosaini et al.

Summary: The study found significantly increased Ki-67 expression in autistic children, with higher numbers of CD3+Ki-67+, CD4+Ki-67+, CD8+Ki-67+ cells compared to typically developing controls. This suggests that Ki-67 may play an important role in autism spectrum disorder.

CHILDREN-BASEL (2021)

Review Immunology

β2 Integrin Regulation of Neutrophil Functional Plasticity and Fate in the Resolution of Inflammation

Meriem Sekheri et al.

Summary: Neutrophils play a crucial role in defending against pathogens and tissue injury, with their functions being tightly regulated and essential for immune responses. Understanding their mechanisms and functional diversity is key to developing novel therapies for resolving inflammation.

FRONTIERS IN IMMUNOLOGY (2021)

Article Immunology

Astragaloside IV Alleviates the Experimental DSS-Induced Colitis by Remodeling Macrophage Polarization Through STAT Signaling

Lianlian Tian et al.

Summary: Inflammatory bowel disease (IBD) is characterized by chronic and relapsing intestinal inflammation, with a lack of safe and effective medicine. Studies have shown that Astragaloside IV (AS-IV) extracted from traditional Chinese medicine can alleviate experimental colitis symptoms by modulating macrophage phenotype transition, potentially offering a new approach for IBD treatment.

FRONTIERS IN IMMUNOLOGY (2021)

Review Biochemistry & Molecular Biology

Interleukin-17A and Keratinocytes in Psoriasis

Masutaka Furue et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2020)

Article Multidisciplinary Sciences

Neutrophil extracellular trap-associated RNA and LL37 enable self-amplifying inflammation in psoriasis

Franziska Herster et al.

NATURE COMMUNICATIONS (2020)

Review Immunology

Role of Neutrophils in Psoriasis

Wen-Ming Wang et al.

JOURNAL OF IMMUNOLOGY RESEARCH (2020)

Review Biochemistry & Molecular Biology

Psoriasis Pathogenesis and Treatment

Adriana Rendon et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2019)

Article Materials Science, Biomaterials

Anti-tumor potential of astragalus polysaccharides on breast cancer cell line mediated by macrophage activation

Wenfang Li et al.

MATERIALS SCIENCE AND ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS (2019)

Review Biotechnology & Applied Microbiology

The Roles of Environmental Factors in Regulation of Oxidative Stress in Plant

Xiulan Xie et al.

BIOMED RESEARCH INTERNATIONAL (2019)

Review Biochemistry & Molecular Biology

Oxidative stress involvement in psoriasis: a systematic review

Serafinella Patrizia Cannavo et al.

FREE RADICAL RESEARCH (2019)

Review Immunology

Neutrophils in Psoriasis

Chih-Chao Chiang et al.

FRONTIERS IN IMMUNOLOGY (2019)

Article Nanoscience & Nanotechnology

Nanozymatic Antioxidant System Based on MoS2 Nanosheets

Tongming Chen et al.

ACS APPLIED MATERIALS & INTERFACES (2018)

Article Pharmacology & Pharmacy

Luteolin attenuates neutrophilic oxidative stress and inflammatory arthritis by inhibiting Raf1 activity

Shun-Chin Yang et al.

BIOCHEMICAL PHARMACOLOGY (2018)

Review Dermatology

Development of psoriasis by continuous neutrophil infiltration into the epidermis

Hiroshi Katayama

EXPERIMENTAL DERMATOLOGY (2018)

Review Biochemistry & Molecular Biology

Neutrophils and redox stress in the pathogenesis of autoimmune disease

Laurence Glennon-Alty et al.

FREE RADICAL BIOLOGY AND MEDICINE (2018)

Article Biochemistry & Molecular Biology

Alcohol-soluble polysaccharide from Astragalus membranaceus: Preparation, characteristics and antitumor activity

Juan Yu et al.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2018)

Article Biochemistry & Molecular Biology

Astragalus membranaceus Extract Attenuates Inflammation and Oxidative Stress in Intestinal Epithelial Cells via NF-κB Activation and Nrf2 Response

Simona Adesso et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2018)

Article Biochemistry & Molecular Biology

Interference of Quercetin on Astragalus Polysaccharide-Induced Macrophage Activation

Zhi-Peng Li et al.

MOLECULES (2018)

Article Clinical Neurology

Systemic inflammation in asocial BTBR T+ tf/J mice predisposes them to increased psoriatic inflammation

Ahmed Nadeem et al.

PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY (2018)

Review Medicine, Research & Experimental

Cycloastragenol: An exciting novel candidate for age-associated diseases

Yongjie Yu et al.

EXPERIMENTAL AND THERAPEUTIC MEDICINE (2018)

Review Immunology

Neutrophil extracellular traps in immunity and disease

Venizelos Papayannopoulos

NATURE REVIEWS IMMUNOLOGY (2018)

Review Pharmacology & Pharmacy

Research review on the pharmacological effects of astragaloside IV

Lei Li et al.

FUNDAMENTAL & CLINICAL PHARMACOLOGY (2017)

Article Dermatology

Sexy again: the renaissance of neutrophils in psoriasis

Michael P. Schoen et al.

EXPERIMENTAL DERMATOLOGY (2017)

Article Biochemistry & Molecular Biology

Immunomodulatory effect of APS and PSP is mediated by Ca2+-cAMP and TLR4/NF-κB signaling pathway in macrophage

Zhixue Wang et al.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2017)

Article Integrative & Complementary Medicine

Anti-Inflammatory and Immunostimulatory Activities of Astragalosides

Yan Qi et al.

AMERICAN JOURNAL OF CHINESE MEDICINE (2017)

Article Integrative & Complementary Medicine

The Anti-Oxidant and Antitumor Properties of Plant Polysaccharides

Rui Jiao et al.

AMERICAN JOURNAL OF CHINESE MEDICINE (2016)

Article Biochemistry & Molecular Biology

Astragalus polysaccharide modulates ER stress response in an OVA-LPS induced murine model of severe asthma

Yuan Lu et al.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2016)

Article Cell Biology

ROS-dependent signal transduction

Colleen R. Reczek et al.

CURRENT OPINION IN CELL BIOLOGY (2015)

Article Biochemistry & Molecular Biology

Osthol attenuates neutrophilic oxidative stress and hemorrhagic shock-induced lung injury via inhibition of phosphodiesterase 4

Yung-Fong Tsai et al.

FREE RADICAL BIOLOGY AND MEDICINE (2015)

Article Medicine, General & Internal

Psoriasis

Wolf-Henning Boehncke et al.

LANCET (2015)

Review Immunology

Immunology of Psoriasis

Michelle A. Lowes et al.

ANNUAL REVIEW OF IMMUNOLOGY, VOL 32 (2014)

Article Integrative & Complementary Medicine

Astragalus membranaceus Injection combined with conventional treatment for viral myocarditis: A systematic review of randomized controlled trials

Piao Yuan-lin et al.

CHINESE JOURNAL OF INTEGRATIVE MEDICINE (2014)

Article Clinical Neurology

Stroke Alters Respiratory Burst in Neutrophils and Monocytes

Johanna Ruhnau et al.

STROKE (2014)

Article Dermatology

Genetic Epidemiology of Psoriasis

Rashmi Gupta et al.

CURRENT DERMATOLOGY REPORTS (2014)

Review Biochemistry & Molecular Biology

Secondary Metabolites of the Genus Astragalus: Structure and Biological-Activity Update

Li-Peng Yang et al.

CHEMISTRY & BIODIVERSITY (2013)

Review Integrative & Complementary Medicine

Recent Advances in Astragalus membranaceus Anti-Diabetic Research: Pharmacological Effects of Its Phytochemical Constituents

Kojo Agyemang et al.

EVIDENCE-BASED COMPLEMENTARY AND ALTERNATIVE MEDICINE (2013)

Review Cell Biology

ROS production in phagocytes: why, when, and where?

Sophie Dupre-Crochet et al.

JOURNAL OF LEUKOCYTE BIOLOGY (2013)

Article Biochemistry & Molecular Biology

Anti-Inflammatory Cycloartane-Type Saponins of Astragalus membranaceus

Dae-Young Lee et al.

MOLECULES (2013)

Article Biochemistry & Molecular Biology

Anti-neutrophilic inflammatory steroidal glycosides from Solanum torvum

Chia-Lin Lee et al.

PHYTOCHEMISTRY (2013)

Article Dermatology

Assessment of an imiquimod-induced psoriatic mouse model in relation to oxidative stress

Jin-Ok Baek et al.

ARCHIVES OF DERMATOLOGICAL RESEARCH (2012)

Article Biochemistry & Molecular Biology

Mitochondrial Protection and Anti-aging Activity of Astragalus Polysaccharides and Their Potential Mechanism

Xing-Tai Li et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2012)

Article Biochemical Research Methods

NIH Image to ImageJ: 25 years of image analysis

Caroline A. Schneider et al.

NATURE METHODS (2012)

Article Pharmacology & Pharmacy

NADPH oxidase (NOX) isoforms are inhibited by celastrol with a dual mode of action

Vincent Jaquet et al.

BRITISH JOURNAL OF PHARMACOLOGY (2011)

Review Biochemistry & Molecular Biology

Oxidative stress in the pathogenesis of psoriasis

Qiang Zhou et al.

FREE RADICAL BIOLOGY AND MEDICINE (2009)

Article Plant Sciences

Anti-inflammatory effects of the extract of indigo naturalis in human neutrophils

Yin-Ku Lin et al.

JOURNAL OF ETHNOPHARMACOLOGY (2009)

Article Immunology

Macrophage activation by polysaccharide isolated from Astragalus membranaceus

KY Lee et al.

INTERNATIONAL IMMUNOPHARMACOLOGY (2005)

Article Agriculture, Multidisciplinary

Free radicals scavenging efficiency of a few naturally occurring flavonoids: A comparative study

M Rajendran et al.

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY (2004)

Review Immunology

Neutrophil granules and secretory vesicles in inflammation

M Faurschou et al.

MICROBES AND INFECTION (2003)