期刊
CURRENT CARDIOLOGY REPORTS
卷 23, 期 11, 页码 -出版社
SPRINGER
DOI: 10.1007/s11886-021-01594-0
关键词
Intracerebral hemorrhage; Stroke prevention; Blood pressure; Statin; Antithrombotic therapy; Atrial fibrillation
Stroke prevention after intracerebral hemorrhage is crucial for long-term outcomes, with interventions such as blood pressure management, cholesterol control, statin therapy, anticoagulation in atrial fibrillation, and left atrial appendage occlusion showing promise in improving patient prognosis. However, further research is needed to address current controversies and knowledge gaps in this area.
Purpose of Review Patients after intracerebral hemorrhage (ICH) are at high risk of both ischemic stroke and recurrent ICH, and stroke prevention after ICH is important to improve the long-term outcomes in this patient population. The objective of this article is to review the current guidelines on stroke prevention measures after ICH as well as the new findings and controversies for future guidance. Recent Findings Intensive blood pressure reduction might benefit ICH survivors significantly. Cholesterol levels and the risk of ICH have an inverse relationship, but statin therapy after ICH might be still beneficial. Anticoagulation in atrial fibrillation after ICH specifically with novel oral anticoagulants may be associated with better long-term outcomes. Left atrial appendage occlusion may be an alternative for stroke prevention in ICH survivors with atrial fibrillation for whom long-term anticoagulation therapy is contraindicated. While complete individualized risk assessment is imperative to prevent stroke after ICH, future research is required to address current controversies and knowledge gap in this topic.
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