Synthesis of Conjugated Dienes in Natural Compounds

This review describes the various synthetic methods commonly used to obtain molecules possessing conjugated dienes. We focus on methods involving cross-coupling reactions using various metals such as nickel, palladium, ruthenium, cobalt, cobalt/zinc, manganese, zirconium, or iron, mainly through examples that aimed to access natural molecules or their analogues. Among the natural molecules covered in this review, we discuss the total synthesis of a phytohormone, Acid Abscisic (ABA), carried out by our team involving the development of a conjugated diene chain.

Automated summary

This review focuses on commonly used synthetic methods to obtain molecules with conjugated dienes. The methods discussed mainly involve cross-coupling reactions using metals such as nickel, palladium, ruthenium, cobalt, cobalt/zinc, manganese, zirconium, or iron. Through examples, the review explores the synthesis of natural molecules or their analogues. Specifically, the total synthesis of the phytohormone Acid Abscisic (ABA) by the author's team is discussed, which involves the development of a conjugated diene chain.