☆ 4.6 Article

Batch and Flow Nitroaldol Synthesis Catalysed by Granulicella tundricola Hydroxynitrile Lyase Immobilised on Celite R-633

CATALYSTS (2022)

相关参考文献

注意：仅列出部分参考文献，下载原文获取全部文献信息。

Article Energy & Fuels

Bioprocess intensification: A route to efficient and sustainable biocatalytic transformations for the future

K. V. K. Boodhoo et al.

Summary: Bioprocessing is an ideal choice for sustainable processing. By developing intensified bioprocesses and utilizing advanced technologies such as biocatalyst engineering and high density cell immobilization, the productivity and competitiveness of bioprocessing can be enhanced. However, there are still challenges to overcome in bioprocess intensification.

CHEMICAL ENGINEERING AND PROCESSING-PROCESS INTENSIFICATION (2022)

添加到收藏夹

Review Chemistry, Multidisciplinary

Reaching New Biocatalytic Reactivity Using Continuous Flow Reactors

Sebastian C. Cosgrove et al.

Summary: The use of flow reactors in biocatalysis has increased significantly in recent years, with chemists designing flow systems that allow enzymes to go beyond the limitations of batch reactions. There is a growing trend towards fully continuous systems, with flow chemistry being seen as an enabling technology for automated synthesis. Advances in AI-assisted enzyme design have opened up the possibility of fully automating the development and implementation of continuous biocatalytic processes, leading to significant improvements in enzyme processes for synthesis.

CHEMISTRY-A EUROPEAN JOURNAL (2022)

添加到收藏夹

Article Biochemistry & Molecular Biology

Immobilized Arabidopsis thaliana Hydroxynitrile Lyase-Catalyzed Retro-Henry Reaction in the Synthesis of (S)-β-Nitroalcohols

D. H. Sreenivasa Rao et al.

Summary: Enantiopure beta-nitroalcohols are versatile intermediates for the synthesis of pharmaceuticals and chiral synthons. This study demonstrated that immobilized AtHNL catalyzes the preparation of (S)-beta-nitroalcohols from racemic mixtures through retro-Henry reaction with increased efficiency and pH stability. The enzyme showed a broad substrate selectivity and produced products with high enantiomeric excess up to 98.5%.

APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY (2021)

添加到收藏夹

Article Environmental Sciences

Value Conflicts in Designing for Safety: Distinguishing Applications of Safe-by-Design and the Inherent Safety Principles

Britte Bouchaut et al.

Summary: This paper examines the differences between Inherent Safety Principles (ISP) and Safe-by-Design (SbD), focusing on their different emphasis on safety values and their suitability for fundamental and applied research. The conclusion drawn is that ISP is better at handling lock-ins in applied research, while SbD may be more suitable for fundamental research.

INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH (2021)

添加到收藏夹

Review Chemistry, Multidisciplinary

Immobilisation and flow chemistry: tools for implementing biocatalysis

Jose Coloma et al.

Summary: The merger of enzyme immobilisation and flow chemistry has attracted attention for its potential in enhancing efficiency and sustainability. Important metrics for successful enzyme immobilisation and reporting flow biocatalytic processes include recycling and relevant examples in different systems. Recent developments have also focused on addressing the hurdle of cofactor recycling.

CHEMICAL COMMUNICATIONS (2021)

添加到收藏夹

Review Chemistry, Multidisciplinary

Development of a continuous-flow system with immobilized biocatalysts towards sustainable bioprocessing

Apisit Naramittanakul et al.

Summary: Immobilization methods are important for increasing the reusability of biocatalysts and simplifying their separation from products in continuous-flow systems. Considerations for developing successful biocatalyst-based continuous-flow systems include immobilization techniques, mass transfer, and reactor design, with sustainability aspects highlighted.

REACTION CHEMISTRY & ENGINEERING (2021)

添加到收藏夹

Review Chemistry, Multidisciplinary

Flow biocatalysis 101: design, development and applications

Ana I. Benitez-Mateos et al.

Summary: This tutorial review introduces the key concepts of flow biocatalysis, guides the reader through its advantages, and highlights current trends in the field to encourage innovative applications of enzymes in flow reactors.

REACTION CHEMISTRY & ENGINEERING (2021)

添加到收藏夹

Review Chemistry, Organic

Biocatalytic approaches for enantio and diastereoselective synthesis of chiral β-nitroalcohols

D. H. Sreenivasa Rao et al.

Summary: Chiral beta-nitroalcohols are important building blocks in organic synthesis, and biocatalytic methods have gained significant importance for their asymmetric synthesis. Different biocatalytic strategies, such as kinetic resolution and Henry reaction, have been developed for the asymmetric synthesis of beta-nitroalcohol stereoisomers.

ORGANIC & BIOMOLECULAR CHEMISTRY (2021)

添加到收藏夹

Article Chemistry, Physical

Bacillus subtilis Lipase A-Lipase or Esterase?

Paula Bracco et al.

CATALYSTS (2020)

添加到收藏夹

Article Chemistry, Physical

Immobilization ofArabidopsis thalianaHydroxynitrile Lyase (AtHNL) on EziG Opal

Jose Coloma et al.

CATALYSTS (2020)

添加到收藏夹

Review Chemistry, Multidisciplinary

The rise of continuous flow biocatalysis - fundamentals, very recent developments and future perspectives

Piera De Santis et al.

REACTION CHEMISTRY & ENGINEERING (2020)

添加到收藏夹

Article Biochemistry & Molecular Biology

Production of (S)-β-Nitro Alcohols by Enantioselective C-C Bond Cleavage with an R-Selective Hydroxynitrile Lyase

D. H. Sreenivasa Rao et al.

CHEMBIOCHEM (2019)

添加到收藏夹

Article Chemistry, Organic

Ketoreductase catalyzed stereoselective bioreduction of α-nitro ketones

Zexu Wang et al.

ORGANIC & BIOMOLECULAR CHEMISTRY (2019)

添加到收藏夹

Article Chemistry, Physical

Hydroxynitrile lyases covalently immobilized in continuous flow microreactors

Michelle P. van der Helm et al.

CATALYSIS SCIENCE & TECHNOLOGY (2019)

添加到收藏夹

Article Chemistry, Physical

Immobilization of Prunus amygdalus Hydroxynitrile Lyase on Celite

Paula Bracco et al.

CATALYSTS (2018)

添加到收藏夹

Article Chemistry, Physical

Biocatalytic Approach to Chiral β-Nitroalcohols by Enantioselective Alcohol Dehydrogenase-Mediated Reduction of α-Nitroketones

Francesca Tentori et al.

CATALYSTS (2018)

添加到收藏夹

Article Chemistry, Organic

An Orthogonal Biocatalytic Approach for the Safe Generation and Use of HCN in a Multistep Continuous Preparation of Chiral O-Acetylcyanohydrins

Aischarya Brahma et al.

SYNLETT (2016)

添加到收藏夹

Review Biochemistry & Molecular Biology

Candida parapsilosis: A versatile biocatalyst for organic oxidation-reduction reactions

Anju Chadha et al.

BIOORGANIC CHEMISTRY (2016)

添加到收藏夹

Article Chemistry, Multidisciplinary

Catalytic Promiscuity of Ancestral Esterases and Hydroxynitrile Lyases

Titu Devamani et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2016)

添加到收藏夹

Article Chemistry, Inorganic & Nuclear

Asymmetric Henry reaction catalyzed by Cu(II)-based chiral amino alcohol complexes with C2-symmetry

Gonghao Lu et al.

TETRAHEDRON-ASYMMETRY (2016)

添加到收藏夹

Article Chemistry, Physical

(R)-Selective Nitroaldol Reaction Catalyzed by Metal-Dependent Bacterial Hydroxynitrile Lyases

Myria Bekerle-Bogner et al.

CHEMCATCHEM (2016)

添加到收藏夹

Article Chemistry, Multidisciplinary

Evaluation of the nitroaldol reaction in the presence of metal ion-crosslinked alginates

Dennis Kuehbeck et al.

NEW JOURNAL OF CHEMISTRY (2015)

添加到收藏夹

Article Chemistry, Multidisciplinary

Enantio- & chemo-selective preparation of enantiomerically enriched aliphatic nitro alcohols using Candida parapsilosis ATCC 7330

Sowmyalakshmi Venkataraman et al.

RSC ADVANCES (2015)

添加到收藏夹

Article Chemistry, Physical

Improving the Properties of Bacterial R-Selective Hydroxynitrile Lyases for Industrial Applications

Romana Wiedner et al.

CHEMCATCHEM (2015)

添加到收藏夹

Article Biochemistry & Molecular Biology

Increasing the Reaction Rate of Hydroxynitrile Lyase from Hevea brasiliensis toward Mandelonitrile by Copying Active Site Residues from an Esterase that Accepts Aromatic Esters

Jan von Langermann et al.

CHEMBIOCHEM (2014)

添加到收藏夹

Article Chemistry, Physical

Immobilized Hydroxynitrile Lyase: A Comparative Study of Recyclability

Guzman Torrelo et al.

CHEMCATCHEM (2014)

添加到收藏夹

Article Chemistry, Multidisciplinary

Double parallel dynamic resolution through lipase-catalyzed asymmetric transformation

Yan Zhang et al.

CHEMICAL COMMUNICATIONS (2013)

添加到收藏夹

Review Chemistry, Organic

Biocatalytic Approaches to the Henry (Nitroaldol) Reaction

Sinead E. Milner et al.

EUROPEAN JOURNAL OF ORGANIC CHEMISTRY (2012)

添加到收藏夹

Article Chemistry, Applied

Hydroxynitrile Lyase from Arabidopsis thaliana: Identification of Reaction Parameters for Enantiopure Cyanohydrin Synthesis by Pure and Immobilized Catalyst

Daniel Okrob et al.

ADVANCED SYNTHESIS & CATALYSIS (2011)

添加到收藏夹

Article Biotechnology & Applied Microbiology

Synthesis of (R)-β-nitro alcohols catalyzed by R-selective hydroxynitrile lyase from Arabidopsis thaliana in the aqueous-organic biphasic system

Ken-ichi Fuhshuku et al.

JOURNAL OF BIOTECHNOLOGY (2011)

添加到收藏夹

Article Chemistry, Physical

Asymmetric Retro-Henry Reaction Catalyzed by Hydroxynitrile Lyase from Hevea brasiliensis

Ruslan Yuryev et al.

CHEMCATCHEM (2010)

添加到收藏夹

Article Chemistry, Multidisciplinary

Activity and Enantioselectivity of the Hydroxynitrile Lyase MeHNL in Dry Organic Solvents

Monica Paravidino et al.

CHEMISTRY-A EUROPEAN JOURNAL (2010)

添加到收藏夹

Review Chemistry, Multidisciplinary

Understanding enzyme immobilisation

Ulf Hanefeld et al.

CHEMICAL SOCIETY REVIEWS (2009)

添加到收藏夹

Article Chemistry, Applied

Direct asymmetric dynamic kinetic resolution by combined lipase catalysis and nitroaldol (Henry) reaction

Pornrapee Vongvilai et al.

ADVANCED SYNTHESIS & CATALYSIS (2008)

添加到收藏夹

Article Biochemistry & Molecular Biology

Catalytic promiscuity of halohydrin dehalogenase and its application in enantioselective epoxide ring opening

Ghannia Hasnaoui-Dijoux et al.

CHEMBIOCHEM (2008)

添加到收藏夹

Article Biochemistry & Molecular Biology

Stereoselective anti-Prelog reduction of ketones by whole cells of Comamonas testosteroni in a 'substrate-coupled' approach

Sabine R. Wallner et al.

JOURNAL OF MOLECULAR CATALYSIS B-ENZYMATIC (2008)

添加到收藏夹

Article Chemistry, Applied

Hydroxynitrile lyase-catalyzed enzymatic nitroaldol (Henry) reaction

Mandana Gruber-Khadjawi et al.

ADVANCED SYNTHESIS & CATALYSIS (2007)

添加到收藏夹

Article Chemistry, Multidisciplinary

Dynamic combinatorial resolution: Direct asymmetric lipase-mediated screening of a dynamic nitroaldol library

Pornrapee Vongvilai et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2007)

添加到收藏夹

Article Chemistry, Inorganic & Nuclear

Straightforward chemo-enzymatic synthesis of new aminocyclitols, analogues of valiolamine and their evaluation as glycosidase inhibitors

Lahssen El Blidi et al.

TETRAHEDRON-ASYMMETRY (2006)

添加到收藏夹

Article Chemistry, Multidisciplinary

A biocatalytic Henry reaction - The hydroxynitrile lyase from Hevea brasiliensis also catalyzes nitroaldol reactions

Thomas Purkarthofer et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2006)

添加到收藏夹

Article Chemistry, Inorganic & Nuclear

Nitrite-mediated hydrolysis of epoxides catalyzed by halohydrin dehalogenase from Agrobacterium radiobacter AD1:: a new tool for the kinetic resolution of epoxides

G Hasnaoui et al.

TETRAHEDRON-ASYMMETRY (2005)

添加到收藏夹

© Peeref 2019-2024. All rights reserved.