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Herbal medicine derived carbon dots: synthesis and applications in therapeutics, bioimaging and sensing

期刊

JOURNAL OF NANOBIOTECHNOLOGY
卷 19, 期 1, 页码 -

出版社

BMC
DOI: 10.1186/s12951-021-01072-3

关键词

Herbal medicine; Carbon dots; Synthesis; Theranostics; Medical applications; Nanomedicine

资金

  1. Project of Inheritance Studio for National Famous Experts of Traditional Chinese Medicine [[2018]134]
  2. Fundamental Research Funds for the Central Universities of Central South University [2021zzts1028]
  3. Innovation-Driven Project of Central South University [2020CX047]

向作者/读者索取更多资源

This article outlines the current research status of herbal medicine as a precursor material for the synthesis of carbon dots in medical field, emphasizing its potential value in areas such as treatment and diagnosis. The analysis of herbal medicine precursors and HM-CDs synthetic methods and characteristics are provided, summarizing their applications in medical therapeutics, bioimaging, and other fields. The crucial challenges and future prospects of HM-CDs are also discussed.
Since the number of raw material selections for the synthesis of carbon dots (CDs) has grown extensively, herbal medicine as a precursor receives an increasing amount of attention. Compared with other biomass precursors, CDs derived from herbal medicine (HM-CDs) have become the most recent incomer in the family of CDs. In recent ten years, a great many studies have revealed that HM-CDs tend to be good at theranostics without drug loading. However, the relevant development and research results are not systematically reviewed. Herein, the origin and history of HM-CDs are outlined, especially their functional performances in medical diagnosis and treatment. Besides, we sort out the herbal medicine precursors, and analyze the primary synthetic methods and the key characteristics. In terms of the applications of HM-CDs, medical therapeutics, ion and molecular detection, bioimaging, as well as pH sensing are summarized. Finally, we discuss the crucial challenges and future prospects.

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