4.6 Article

Promoting high T2 contrast in Dy-doped MSNs through Curie effects

期刊

JOURNAL OF MATERIALS CHEMISTRY B
卷 10, 期 2, 页码 302-305

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ROYAL SOC CHEMISTRY
DOI: 10.1039/d1tb01894a

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资金

  1. Novo Nordisk Foundation [NNF21OC0068683]
  2. British Heart Foundation [RE/08/004]

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By adjusting the Dy3+ loading density within a mesoporous silica architecture, the dominant Curie effect can be effectively tuned to optimize T-2 contrast at high magnetic fields up to 11.7 T, enhancing image sensitivity in MRI scans.
Contrast agents retaining high relaxivities at ultrahigh magnetic fields underpin an enhanced image sensitivity within derived MRI scans. By varying the Dy3+ loading density inside a mesoporous silica architecture the dominant Curie effect can be effectively tuned so as to optimise T-2 contrast at magnetic fields as high as 11.7 T.

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