4.7 Editorial Material

Exercise-microbiota interactions in aging-related sarcopenia

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Summary: This systematic review analyzed the evidence on the effects of gut microbiota on muscle/sarcopenia, showing that altering the gut microbiota can directly affect muscle phenotypes. Probiotics, prebiotics, short-chain fatty acids, and bacterial products are potential novel therapies to enhance muscle mass and physical performance. The potential mechanisms of microbiome modulating muscle include protein, energy, lipid, and glucose metabolism, inflammation level, neuromuscular junction, and mitochondrial function.

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