期刊
GENETICS
卷 220, 期 4, 页码 -出版社
GENETICS SOCIETY AMERICA
DOI: 10.1093/genetics/iyab223
关键词
model organism database; Schizosaccharomyces japonicus; genome; annotation; curation; evolution
资金
- Wellcome Trust [103741/Z/14/Z, 220790/Z/20/Z, FC001002, 218236/Z/19/Z]
- BBSRC [BB/T000481/1]
- Cancer Research UK [FC001002]
- UK Medical Research Council [FC001002]
- BBSRC [BB/T000481/1] Funding Source: UKRI
- Wellcome Trust [220790/Z/20/Z, 218236/Z/19/Z, 103741/Z/14/Z] Funding Source: Wellcome Trust
The fission yeast Schizosaccharomyces japonicus has become an important system for studying cellular process evolution, utilizing similarities and differences with the established model organism Schizosaccharomyces pombe. By deploying open-source code and tools, JaponicusDB provides a central resource for S. japonicus researchers, supporting their studies and integration of new data.
The fission yeast Schizosaccharomyces japonicus has recently emerged as a powerful system for studying the evolution of essential cellular processes, drawing on similarities as well as key differences between S. japonicus and the related, well-established model Schizosaccharomyces pombe. We have deployed the open-source, modular code and tools originally developed for PomBase, the S. pombe model organism database (MOD), to create JaponicusDB (www.japonicusdb.org), a new MOD dedicated to S. japonicus. By providing a central resource with ready access to a growing body of experimental data, ontology-based curation, seamless browsing and querying, and the ability to integrate new data with existing knowledge, JaponicusDB supports fission yeast biologists to a far greater extent than any other source of S. japonicus data. JaponicusDB thus enables S. japonicus researchers to realize the full potential of studying a newly emerging model species and illustrates the widely applicable power and utility of harnessing reusable PomBase code to build a comprehensive, community-maintainable repository of species-relevant knowledge.
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