Roles of Type VI Secretion System in Transport of Metal Ions

The type VI secretion system (T6SS) is a transmembrane protein nanomachine employed by many gram-negative bacteria to directly translocate effectors into adjacent cells or the extracellular milieu, showing multiple functions in both interbacterial competition and bacteria-host interactions. Metal ion transport is a newly discovered T6SS function. This review summarizes the identified T6SS functions and highlights the features of metal ion transport mediated by T6SS and discusses its regulation.

Automated summary

The type VI secretion system (T6SS) in gram-negative bacteria has multiple functions, including the newly discovered function of metal ion transport. The review provides a summary of identified T6SS functions and discusses the features and regulation of metal ion transport mediated by T6SS.