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注意:仅列出部分参考文献,下载原文获取全部文献信息。TAZ Is a Negative Regulator of PPARγ Activity in Adipocytes and TAZ Deletion Improves Insulin Sensitivity and Glucose Tolerance
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JOURNAL OF BIOLOGICAL CHEMISTRY (2018)
Hippo-mediated suppression of IRS2/AKT signaling prevents hepatic steatosis and liver cancer
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Hippo Signaling in the Liver Regulates Organ Size, Cell Fate, and Carcinogenesis
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YAP Suppresses Gluconeogenic Gene Expression Through PGC1α
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HEPATOLOGY (2017)
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mTOR Signaling in Growth, Metabolism, and Disease
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Hepatocyte TAZ/WWTR1 Promotes Inflammation and Fibrosis in Nonalcoholic Steatohepatitis
Xiaobo Wang et al.
CELL METABOLISM (2016)
Hepatic Glucocorticoid Receptor Plays a Greater Role Than Adipose GR in Metabolic Syndrome Despite Renal Compensation
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TRENDS IN ENDOCRINOLOGY AND METABOLISM (2015)
Flavin-containing monooxygenase 3 as a potential player in diabetes-associated atherosclerosis
Ji Miao et al.
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Hippo Pathway Activity Influences Liver Cell Fate
Dean Yimlamai et al.
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MOLECULAR ENDOCRINOLOGY (2014)
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Prevalence of oral glucocorticoid usage in the United States: A general population perspective
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Targeted deletion of liver glucose-6 phosphatase mimics glycogen storage disease type 1a including development of multiple adenomas
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JOURNAL OF HEPATOLOGY (2011)
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TEAD Transcription Factors Mediate the Function of TAZ in Cell Growth and Epithelial-Mesenchymal Transition
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JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
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SCIENCE (2009)
Mammalian Tead proteins regulate cell proliferation and contact inhibition as transcriptional mediators of Hippo signaling
Mitsunori Ota et al.
DEVELOPMENT (2008)
TEAD mediates YAP-dependent gene induction and growth control
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GENES & DEVELOPMENT (2008)
TAZ promotes cell proliferation and epithelial-mesenchymal transition and is inhibited by the hippo pathway
Qun-Ying Lei et al.
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Yap1 phosphorylation by c-AbI is a critical step in selective activation of proapoptotic genes in response to DNA damage
Dan Levy et al.
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PML, YAP, and p73 Are Components of a Proapoptotic Autoregulatory Feedback Loop
Eleonora Lapi et al.
MOLECULAR CELL (2008)
Multiple renal cysts, urinary concentration defects, and pulmonary emphysematous changes in mice lacking TAZ
Ryosuke Makita et al.
AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY (2008)
Glucocorticoid receptor physiology
Marjet D. Heitzer et al.
REVIEWS IN ENDOCRINE & METABOLIC DISORDERS (2007)
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MOLECULAR AND CELLULAR ENDOCRINOLOGY (2007)
A protocol for rapid generation of recombinant adenoviruses using the AdEasy system
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Functional inhibitory cross-talk between constitutive androstane receptor and hepatic nuclear factor-4 in hepatic lipid/glucose metabolism is mediated by competition for binding to the DR1 motif and to the common coactivators, GRIP-1 and PGC-1α
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JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Irs1 and Irs2 signaling is essential for hepatic glucose homeostasis and systemic growth
XC Dong et al.
JOURNAL OF CLINICAL INVESTIGATION (2006)
Defects in yolk sac vasculogenesis, chorioallantoic fusion, and embryonic axis elongation in mice with targeted disruption of Yap65
EM Morin-Kensicki et al.
MOLECULAR AND CELLULAR BIOLOGY (2006)
A WW domain protein TAZ is a critical coactivator for TBX5, a transcription factor implicated in Holt-Oram syndrome
M Murakami et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
The glucose-6-phosphatase catalytic subunit gene promoter contains both positive and negative glucocorticoid response elements
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MOLECULAR ENDOCRINOLOGY (2005)
TAZ, a transcriptional modulator of mesenchymal stem cell differentiation
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Hepatic glucocorticoid receptor antagonism is sufficient to reduce elevated hepatic glucose output and improve glucose control in animal models of type 2 diabetes
PB Jacobson et al.
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The search for safer glucocorticoid receptor ligands
J Rosen et al.
ENDOCRINE REVIEWS (2005)
Inactivation of the glucocorticoid receptor in hepatocytes leads to fasting hypoglycemia and ameliorates hyperglycemia in streptozotocin-induced diabetes mellitus
C Opherk et al.
MOLECULAR ENDOCRINOLOGY (2004)
WW domain-containing protein YAP associates with ErbB-4 and acts as a co-transcriptional activator for the carboxyl-terminal fragment of ErbB-4 that translocates to the nucleus
A Komuro et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
RU486-induced glucocorticoid receptor agonism is controlled by the receptor N terminus and by corepressor binding
M Schulz et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Repression of inflammatory responses in the absence of DNA binding by the glucocorticoid receptor
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EMBO JOURNAL (2001)
TAZ: a novel transcriptional co-activator regulated by interactions with 14-3-3 and PDZ domain proteins
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EMBO JOURNAL (2000)
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Phosphoenolpyruvate carboxykinase is necessary for the integration of hepatic energy metabolism
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