期刊
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
卷 92, 期 -, 页码 37-48出版社
ELSEVIER SCIENCE BV
DOI: 10.1016/j.ijbiomac.2016.06.100
关键词
Polysaccharide; Bioactivity; Isolation; Purification
资金
- Translational and Innovation Fund of Ministry of Education, Singapore [MOE2012-TIF-1-G-065]
Polysaccharides play multiple roles and have extensive bioactivities in life process and an immense potential in healthcare, food and cosmetic industries, due to their therapeutic effects and relatively low toxicity. This review describes their major functions involved in antitumor, anti-virus, and anti-inflammatory bioactivities. Due to their enormous structural heterogeneity, the approaches for isolation and purification of polysaccharides are distinct from that of the other macromolecules such as proteins, etc. Yet, to achieve the homogeneity is the initial step for studies of polysaccharide structure, pharmacology, and its structure-activity relationships. According to the experiences accumulated by our lab and the published literatures, this review also introduces the methods widely used in isolation and purification of polysaccharides. (C) 2016 Elsevier B.V. All rights reserved.
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