期刊
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
卷 93, 期 -, 页码 1338-1353出版社
ELSEVIER
DOI: 10.1016/j.ijbiomac.2016.03.041
关键词
Bioceramics; Chitin; Chitosan; Nanocomposite scaffolds; Bone tissue engineering
资金
- SERB Division, Department of Science and Technology (DST), Government of India [SR/S1/OC-19/2012]
- Council of Scientific and Industrial Research under the CSIR-SRF [9/963(0034)2K13-EMR-I]
Chitin and chitosan based nanocomposite scaffolds have been widely used for bone tissue engineering. These chitin and chitosan based scaffolds were reinforced with nanocomponents viz Hydroxyapatite (HAp), Bioglass ceramic (BGC), Silicon dioxide (SiO2), Titanium dioxide (TiO2) and Zirconium oxide (ZrO2) to develop nanocomposite scaffolds. Plenty of works have been reported on the applications and characteristics of the nanoceramic composites however, compiling the work done in this field and presenting it in a single article is a thrust area. This review is written with an aim to fill this gap and focus on the preparations and applications of chitin or chitosan/nHAp, chitin or chitosan/nBGC, chitin or chitosan/nSiO(2), chitin or chitosan/nTiO(2) and chitin or chitosan/nZrO(2) in the field of bone tissue engineering in detail. Many reports so far exemplify the importance of ceramics in bone regeneration. The effect of nanoceramics over native ceramics in developing composites, its role in osteogenesis etc. are the gist of this review. (C) 2016 Elsevier B.V. All rights reserved.
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