4.7 Article

Fibrin(ogen) engagement of S. aureus promotes the host antimicrobial response and suppression of microbe dissemination following peritoneal infection

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Summary: This study identifies the essential role of the fibrinogen in combating Staphylococcus aureus infection, which relies on the coagulant function of thrombin. The bacteria-derived prothrombin activator vWbp is crucial for the fibrinogen-mediated bacterial clearance.

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