4.6 Article

Transcriptomic profiling in canines and humans reveals cancer specific gene modules and biological mechanisms common to both species

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Multidisciplinary Sciences

Fat1 deletion promotes hybrid EMT state, tumour stemness and metastasis

Ievgenia Pastushenko et al.

Summary: This study reveals that mutation of the FAT1 gene promotes tumor initiation, progression, invasiveness, stemness, and metastasis. Loss of function of FAT1 activates a CAMK2-CD44-SRC axis while inactivates EZH2, playing important roles in the expression of YAP1 and ZEB1.

NATURE (2021)

Review Cell Biology

MYC's Fine Line Between B Cell Development and Malignancy

Oriol de Barrios et al.

Article Biochemistry & Molecular Biology

Nucleotide depletion reveals the impaired ribosome biogenesis checkpoint as a barrier against DNA damage

Joffrey Pelletier et al.

EMBO JOURNAL (2020)

Article Genetics & Heredity

Application of Transcriptional Gene Modules to Analysis of Caenorhabditis elegans' Gene Expression Data

Michael Cary et al.

G3-GENES GENOMES GENETICS (2020)

Review Oncology

Improving human cancer therapy through the evaluation of pet dogs

Amy K. LeBlanc et al.

NATURE REVIEWS CANCER (2020)

Article Biochemistry & Molecular Biology

Genomic and transcriptomic profiling expands precision cancer medicine: the WINTHER trial

Jordi Rodon et al.

NATURE MEDICINE (2019)

Article Genetics & Heredity

A modular transcriptome map of mature B cell lymphomas

Henry Loeffler-Wirth et al.

GENOME MEDICINE (2019)

Article Genetics & Heredity

Cross-Species Gene Expression Analysis Reveals Gene Modules Implicated in Human Osteosarcoma

Zheng Jin et al.

FRONTIERS IN GENETICS (2019)

Article Biochemistry & Molecular Biology

COSMIC: the Catalogue Of Somatic Mutations In Cancer

John G. Tate et al.

NUCLEIC ACIDS RESEARCH (2019)

Review Oncology

The biology and role of CD44 in cancer progression: therapeutic implications

Chen Chen et al.

JOURNAL OF HEMATOLOGY & ONCOLOGY (2018)

Review Clinical Neurology

Review: The past, present and future challenges in epilepsy-related and sudden deaths and biobanking

M. Thom et al.

NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY (2018)

Review Cell Biology

Exosome-Based Cell-Cell Communication in the Tumor Microenvironment

Joana Maia et al.

FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY (2018)

Article Biochemistry & Molecular Biology

Pharos: Collating protein information to shed light on the druggable genome

Dac-Trung Nguyen et al.

NUCLEIC ACIDS RESEARCH (2017)

Article Biochemistry & Molecular Biology

The Comparative Toxicogenomics Database: update 2017

Allan Peter Davis et al.

NUCLEIC ACIDS RESEARCH (2017)

Article Biochemistry & Molecular Biology

KEGG: new perspectives on genomes, pathways, diseases and drugs

Minoru Kanehisa et al.

NUCLEIC ACIDS RESEARCH (2017)

Review Cell Biology

Ethical Legal and Social Issues of Biobanking: Past, Present, and Future

Marianna J. Bledsoe

BIOPRESERVATION AND BIOBANKING (2017)

Article Endocrinology & Metabolism

Molecular genetics of osteosarcoma

Kirby Rickel et al.

Article Biotechnology & Applied Microbiology

A comprehensive genomic pan-cancer classification using The Cancer Genome Atlas gene expression data

Yuanyuan Li et al.

BMC GENOMICS (2017)

Article Oncology

Defining the Value of a Comparative Approach to Cancer Drug Development

Amy K. LeBlanc et al.

CLINICAL CANCER RESEARCH (2016)

Article Oncology

FAT1: a potential target for monoclonal antibody therapy in colon cancer

Piero Pileri et al.

BRITISH JOURNAL OF CANCER (2016)

Editorial Material Cell Biology

Using the mouse to model human disease: increasing validity and reproducibility

Monica J. Justice et al.

DISEASE MODELS & MECHANISMS (2016)

Article Hematology

High miR-34a expression improves response to doxorubicin in diffuse large B-cell lymphoma

Sara Correia Marques et al.

EXPERIMENTAL HEMATOLOGY (2016)

Article Biochemistry & Molecular Biology

Canine urothelial carcinoma: genomically aberrant and comparatively relevant

S. G. Shapiro et al.

CHROMOSOME RESEARCH (2015)

Review Medical Laboratory Technology

PI3K/Akt signaling in osteosarcoma

Jian Zhang et al.

CLINICA CHIMICA ACTA (2015)

Review Biology

Comparative oncology: what dogs and other species can teach us about humans with cancer

Joshua D. Schiffman et al.

PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES (2015)

Article Multidisciplinary Sciences

REDD1 Is Essential for Optimal T Cell Proliferation and Survival

Emma L. Reuschel et al.

PLOS ONE (2015)

Article Biochemical Research Methods

HTSeq-a Python framework to work with high-throughput sequencing data

Simon Anders et al.

BIOINFORMATICS (2015)

Article Statistics & Probability

fastcluster: Fast Hierarchical, Agglomerative Clustering Routines forRandPython

Daniel Müllner

Journal of Statistical Software (2015)

Article Biochemistry & Molecular Biology

Gene Ontology Consortium: going forward

J. A. Blake et al.

NUCLEIC ACIDS RESEARCH (2015)

Article Multidisciplinary Sciences

BRAF Mutations in Canine Cancers

Hiroyuki Mochizuki et al.

PLOS ONE (2015)

Editorial Material Veterinary Sciences

Naturally Occurring Diseases in Animals: Contributions to Translational Medicine Introduction

Michael D. Lairmore et al.

ILAR JOURNAL (2014)

Article Multidisciplinary Sciences

Characterization of Chemically Induced Liver Injuries Using Gene Co-Expression Modules

Gregory J. Tawa et al.

PLOS ONE (2014)

Review Oncology

The PT N/PI3K/AKT pathway in vivo, cancer mouse models

Amancio Carnero et al.

FRONTIERS IN ONCOLOGY (2014)

Article Immunology

Biobanking past, present and future: responsibilities and benefits

Yvonne G. De Souza et al.

Article Biochemical Research Methods

STAR: ultrafast universal RNA-seq aligner

Alexander Dobin et al.

BIOINFORMATICS (2013)

Editorial Material Oncology

The Promise of Patient-Derived Xenografts: The Best Laid Plans of Mice and Men

Scott Kopetz et al.

CLINICAL CANCER RESEARCH (2012)

Article Biochemistry & Molecular Biology

ChEMBL: a large-scale bioactivity database for drug discovery

Anna Gaulton et al.

NUCLEIC ACIDS RESEARCH (2012)

Editorial Material Multidisciplinary Sciences

Too many roads not taken

Aled M. Edwards et al.

NATURE (2011)

Article Genetics & Heredity

Statistical Design and Analysis of RNA Sequencing Data

Paul L. Auer et al.

GENETICS (2010)

Article Biochemistry & Molecular Biology

Analytical approaches to RNA profiling data for the identification of genes enriched in specific cells

Joseph D. Dougherty et al.

NUCLEIC ACIDS RESEARCH (2010)

Article Multidisciplinary Sciences

Independent filtering increases detection power for high-throughput experiments

Richard Bourgon et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)

Article Biochemical Research Methods

Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources

Da Wei Huang et al.

NATURE PROTOCOLS (2009)

Article Multidisciplinary Sciences

A Gene Expression Signature of Invasive Potential in Metastatic Melanoma Cells

Aaron R. Jeffs et al.

PLOS ONE (2009)

Review Oncology

Molecular targets in Gastrointestinal Stromal Tumors (GIST) therapy

C. Braconi et al.

CURRENT CANCER DRUG TARGETS (2008)

Review Oncology

Science and society - Translation of new cancer treatments from pet dogs to humans

Melissa Paoloni et al.

NATURE REVIEWS CANCER (2008)

Article Immunology

The SH3-SAM adaptor HACS1 is up-regulated in B cell activation signaling cascades

YX Zhu et al.

JOURNAL OF EXPERIMENTAL MEDICINE (2004)

Article Genetics & Heredity

Revealing modular organization in the yeast transcriptional network

J Ihmels et al.

NATURE GENETICS (2002)

Article Biochemistry & Molecular Biology

Characterization of an activated mutant of focal adhesion kinase: 'SuperFAK'

V Gabarra-Niecko et al.

BIOCHEMICAL JOURNAL (2002)