Project-based learning course on metabolic network modelling in computational systems biology

Project-based learning (PBL) is a dynamic student-centred teaching method that encourages students to solve real-life problems while fostering engagement and critical thinking. Here, we report on a PBL course on metabolic network modelling that has been running for several years within the Master in Integrated Systems Biology (MISB) at the University of Luxembourg. This 2-week full-time block course comprises an introduction into the core concepts and methods of constraint-based modelling (CBM), applied to toy models and large-scale networks alongside the preparation of individual student projects in week 1 and, in week 2, the presentation and execution of these projects. We describe in detail the schedule and content of the course, exemplary student projects, and reflect on outcomes and lessons learned. PBL requires the full engagement of students and teachers and gives a rewarding teaching experience. The presented course can serve as a role model and inspiration for other similar courses.

Automated summary

This article introduces a long-standing project-based learning course within the Master in Integrated Systems Biology program at the University of Luxembourg, which aims to cultivate students' ability to solve real-life problems and promote engagement and critical thinking. The article provides a detailed description of the course schedule and content, showcases student projects, and reflects on the outcomes and lessons learned.