相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。Molecular mechanism and potential target indication of TAK-931, a novel CDC7-selective inhibitor
Kenichi Iwai et al.
SCIENCE ADVANCES (2019)
MTBP, the partner of Treslin, contains a novel DNA-binding domain that is essential for proper initiation of DNA replication
Akiko Kumagai et al.
MOLECULAR BIOLOGY OF THE CELL (2017)
Reversal of DDK-Mediated MCM Phosphorylation by Rif1-PP1 Regulates Replication Initiation and Replisome Stability Independently of ATR/Chk1
Robert C. Alver et al.
CELL REPORTS (2017)
The High-Affinity Interaction between ORC and DNA that Is Required for Replication Licensing Is Inhibited by 2-Arylquinolin-4-Amines
Nicola J. Gardner et al.
CELL CHEMICAL BIOLOGY (2017)
Human RIF1 and protein phosphatase 1 stimulate DNA replication origin licensing but suppress origin activation
Shin-ichiro Hiraga et al.
EMBO REPORTS (2017)
Phosphopeptide binding by Sld3 links Dbf4-dependent kinase to MCM replicative helicase activation
Tom D. Deegan et al.
EMBO JOURNAL (2016)
RecQL4 is required for the association of Mcm10 and Ctf4 with replication origins in human cells
Jun-Sub Im et al.
CELL CYCLE (2015)
Cyclin-dependent kinase regulates the length of S phase through TICRR/TRESLIN phosphorylation
Courtney G. Sansam et al.
GENES & DEVELOPMENT (2015)
Regulated eukaryotic DNA replication origin firing with purified proteins
Joseph T. P. Yeeles et al.
NATURE (2015)
The quaternary structure of the eukaryotic DNA replication proteins Sld7 and Sld3
Hiroshi Itou et al.
ACTA CRYSTALLOGRAPHICA SECTION D-STRUCTURAL BIOLOGY (2015)
Oncogenic Protein MTBP Interacts with MYC to Promote Tumorigenesis
Brian C. Grieb et al.
CANCER RESEARCH (2014)
Rif1 controls DNA replication by directing Protein Phosphatase 1 to reverse Cdc7-mediated phosphorylation of the MCM complex
Shin-ichiro Hiraga et al.
GENES & DEVELOPMENT (2014)
MTBP Is Overexpressed in Triple-Negative Breast Cancer and Contributes to Its Growth and Survival
Brian C. Grieb et al.
MOLECULAR CANCER RESEARCH (2014)
Xenopus Cdc7 executes its essential function early in S phase and is counteracted by checkpoint-regulated protein phosphatase 1
Wei Theng Poh et al.
OPEN BIOLOGY (2014)
Loading and activation of DNA replicative helicases: the key step of initiation of DNA replication
Yan Li et al.
GENES TO CELLS (2013)
Kinetochores Coordinate Pericentromeric Cohesion and Early DNA Replication by Cdc7-Dbf4 Kinase Recruitment
Toyoaki Natsume et al.
MOLECULAR CELL (2013)
Identification of a Heteromeric Complex That Promotes DNA Replication Origin Firing in Human Cells
Dominik Boos et al.
SCIENCE (2013)
Titration of Four Replication Factors Is Essential for the Xenopus laevis Midblastula Transition
Clara Collart et al.
SCIENCE (2013)
Preparation and use of Xenopus egg extracts to study DNA replication and chromatin associated proteins
Peter J. Gillespie et al.
METHODS (2012)
Regulation of DNA Replication through Sld3-Dpb11 Interaction Is Conserved from Yeast to Humans
Dominik Boos et al.
CURRENT BIOLOGY (2011)
Origin Association of SId3, SId7, and Cdc45 Proteins Is a Key Step for Determination of Origin-Firing Timing
Seiji Tanaka et al.
CURRENT BIOLOGY (2011)
Sld7, an Sld3-associated protein required for efficient chromosomal DNA replication in budding yeast
Tamon Tanaka et al.
EMBO JOURNAL (2011)
Limiting replication initiation factors execute the temporal programme of origin firing in budding yeast
Davide Mantiero et al.
EMBO JOURNAL (2011)
MCM2-7 Form Double Hexamers at Licensed Origins in Xenopus Egg Extract
Agnieszka Gambus et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
Direct regulation of Treslin by cyclin-dependent kinase is essential for the onset of DNA replication
Akiko Kumagai et al.
JOURNAL OF CELL BIOLOGY (2011)
Treslin Collaborates with TopBP1 in Triggering the Initiation of DNA Replication
Akiko Kumagai et al.
CELL (2010)
CDK-dependent complex formation between replication proteins Dpb11, Sld2, Pol ε, and GINS in budding yeast
Sachiko Muramatsu et al.
GENES & DEVELOPMENT (2010)
Replication factory activation can be decoupled from the replication timing program by modulating Cdk levels
Alexander M. Thomson et al.
JOURNAL OF CELL BIOLOGY (2010)
Chk1 inhibits replication factory activation but allows dormant origin firing in existing factories
Xin Quan Ge et al.
JOURNAL OF CELL BIOLOGY (2010)
A deficiency in Mdm2 binding protein inhibits Myc-induced B-cell proliferation and lymphomagenesis
J. Odvody et al.
ONCOGENE (2010)
A model for DNA replication showing how dormant origins safeguard against replication fork failure
J. Julian Blow et al.
EMBO REPORTS (2009)
A Cdc7 kinase inhibitor restricts initiation of DNA replication and has antitumor activity
Alessia Montagnoli et al.
NATURE CHEMICAL BIOLOGY (2008)
Excess MCM proteins protect human cells from replicative stress by licensing backup origins of replication
Arkaitz Ibarra et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
Dormant origins licensed by excess Mcm2-7 are required for human cells to survive replicative stress
Xin Quan Ge et al.
GENES & DEVELOPMENT (2007)
CDK-dependent phosphorylation of Sld2 and Sld3 initiates DNA replication in budding yeast
Seiji Tanaka et al.
NATURE (2007)
Phosphorylation of Sld2 and Sld3 by cyclin-dependent kinases promotes DNA replication in budding yeast
Philip Zegerman et al.
NATURE (2007)
Cdc7-Dbf4 phosphorylates MCM proteins via a docking site-mediated mechanism to promote S phase progression
Yi-Jun Sheu et al.
MOLECULAR CELL (2006)
Excess Mcm2-7 license dormant origins of replication that can be used under conditions of replicative stress
Anna M. Woodward et al.
JOURNAL OF CELL BIOLOGY (2006)
Distinct roles for Sld3 and GINS during establishment and progression of eukaryotic DNA replication forks
Masato Kanemaki et al.
EMBO JOURNAL (2006)
GINS maintains association of Cdc45 with MCM in replisome progression complexes at eukaryotic DNA replication forks
A Gambus et al.
NATURE CELL BIOLOGY (2006)
Analysis of the Xenopus Werner syndrome protein in DNA double-strand break repair
H Yan et al.
JOURNAL OF CELL BIOLOGY (2005)
Functional domains of the Xenopus replication licensing factor Cdt1
A Ferenbach et al.
NUCLEIC ACIDS RESEARCH (2005)
The role of Cdc6 in ensuring complete genome licensing and S phase checkpoint activation
M Oehlmann et al.
JOURNAL OF CELL BIOLOGY (2004)
Characterization of a novel ATR-dependent, Chk1-ndependent, intra-S-phase checkpoint that suppresses initiation of replication in Xenopus
MG Luciani et al.
JOURNAL OF CELL SCIENCE (2004)
MCM2-7 complexes bind chromatin in a distributed pattern surrounding the origin recognition complex in Xenopus egg extracts
MC Edwards et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
S-Cdk-dependent phosphorylation of Sld2 essential for chromosomal DNA replication in budding yeast
H Masumoto et al.
NATURE (2002)
Repression of origin assembly in metaphase depends on inhibition of RLF-B/Cdt1 by geminin
S Tada et al.
NATURE CELL BIOLOGY (2001)
Replication origins in Xenopus egg extract are 5-15 kilobases apart and are activated in clusters that fire at different times
JJ Blow et al.
JOURNAL OF CELL BIOLOGY (2001)
Inhibition of eukaryotic DNA replication by geminin binding to Cdt1
JA Wohlschlegel et al.
SCIENCE (2000)
Evidence for sequential action of cdc7 and cdk2 protein kinases during initiation of DNA replication in Xenopus egg extracts
JC Walter
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
A novel cellular protein (MTBP) binds to MDM2 and induces a G1 arrest that is suppressed by MDM2
MT Boyd et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
Sequential MCM/P1 subcomplex assembly is required to form a heterohexamer with replication licensing activity
TA Prokhorova et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)