4.5 Review

Applications of multimodality imaging for left atrial catheter ablation

期刊

出版社

OXFORD UNIV PRESS
DOI: 10.1093/ehjci/jeab205

关键词

atria; atrial fibrillation; MRI; CT; ablation

资金

  1. Medical Research Council Skills Development Fellowship [MR/S015086/1]
  2. British Heart Foundation [PG/15/91/31812, PG/13/37/30280, SP/18/6/33805, FS/20/26/34952, PG/19/44/34368]
  3. UK Engineering and Physical Sciences Research Council [EP/P01268X/1]
  4. US National Institutes of Health [NIH R01-HL152256]
  5. European Research Council [ERC PREDICT-HF 864055]

向作者/读者索取更多资源

Catheter ablation is an effective treatment for atrial arrhythmias such as atrial fibrillation and atrial flutter, with the use of advanced imaging techniques to inform key clinical decisions and treatment approaches. Advanced imaging, combined with specialized image analysis techniques and intra-procedural electrical measurements, may improve outcomes by personalizing ablation targets. Ongoing research aims to integrate imaging with advanced analyses for personalized ablation targets to enhance catheter ablation outcomes in the future.
Atrial arrhythmias, including atrial fibrillation and atrial flutter, may be treated through catheter ablation. The process of atrial arrhythmia catheter ablation, which includes patient selection, pre-procedural planning, intra-procedural guidance, and post-procedural assessment, is typically characterized by the use of several imaging modalities to sequentially inform key clinical decisions. Increasingly, advanced imaging modalities are processed via specialized image analysis techniques and combined with intra-procedural electrical measurements to inform treatment approaches. Here, we review the use of multimodality imaging for left atrial ablation procedures. The article first outlines how imaging modalities are routinely used in the peri-ablation period. We then describe how advanced imaging techniques may inform patient selection for ablation and ablation targets themselves. Ongoing research directions for improving catheter ablation outcomes by using imaging combined with advanced analyses for personalization of ablation targets are discussed, together with approaches for their integration in the standard clinical environment. Finally, we describe future research areas with the potential to improve catheter ablation outcomes.

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