期刊
CURRENT STEM CELL RESEARCH & THERAPY
卷 17, 期 6, 页码 527-536出版社
BENTHAM SCIENCE PUBL LTD
DOI: 10.2174/1574888X17666211229155533
关键词
Human exfoliated deciduous teeth; stem cells; conditioned medium; exosomes; neurological diseases and injuries; therapy
资金
- National Natural Science Foundation of China [81671024]
This article summarizes the biological characteristics of stem cells from human exfoliated deciduous teeth (SHEDs) and their potential role in the prevention and treatment of neurological diseases and injuries.
Stem cells from human exfoliated deciduous teeth (SHEDs) are relatively easy to isolate from exfoliated deciduous teeth, which are obtained via dental therapy as biological waste. SHEDs originate from the embryonic neural crest, and therefore, have considerable potential for neurogenic differentiation. Currently, an increasing amount of research is focused on the therapeutic applications of SHEDs in neurological diseases and injuries. In this article, we summarize the biological characteristics of SHEDs and the potential role of SHEDs and their derivatives, including conditioned medium from SHEDs and the exosomes they secrete, in the prevention and treatment of neurological diseases and injuries.
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