4.7 Review

Natural Biomaterials from Biodiversity for Healthcare Applications

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Review Food Science & Technology

A review on recent advances and applications of fish collagen

Fazli Subhan et al.

Summary: Fish collagen, extracted from discarded fishery resources, has drawn considerable attention from biomedical researchers for its enhanced physicochemical properties, stability, mechanical strength, biocompatibility, and biodegradability. Its growing role in various biomedical applications, such as wound healing, tissue engineering, drug delivery, and cell culture, signifies its commercial importance for the fishing industry, food processors, and biomedical sector.

CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION (2021)

Article Engineering, Biomedical

In vivo osseointegration and erosion of nacre screws in an animal model

Jean-Daniel Kun-Darbois et al.

Summary: The study compared the in vivo osseointegration and erosion of titanium and nacre screws in the femoral condyles of adult rats, demonstrating similar clinical osseointegration but progressive erosion of nacre screws over time. Titanium screws showed stable bone volume/tissue volume (BV/TV) and no erosion, while nacre screws exhibited decreasing volume and erosion specifically within the bone shaft in contact with bone marrow.

JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART B-APPLIED BIOMATERIALS (2021)

Article Materials Science, Textiles

Investigation and comparison of antibacterial property of bamboo plants, natural bamboo fibers and commercial bamboo viscose textiles

Bahrum Prang Rocky et al.

Summary: The study tested the antibacterial activity of various bamboo fiber samples against Staphylococcus aureus and Klebsiella pneumoniae, finding that natural bamboo fiber showed better antibacterial effectiveness compared to commercial bamboo products. The research also revealed that processed bamboo fibers contain more bacteria-killing compounds, leading to higher reductions of bacteria compared to raw bamboo specimens.

JOURNAL OF THE TEXTILE INSTITUTE (2021)

Article Biochemistry & Molecular Biology

Anti-Herpes simplex virus (HSV-1) activity and antioxidant capacity of carrageenan-rich enzymatic extracts from Solieria filiformis (Gigartinales, Rhodophyta)

Penuela Ana et al.

Summary: This study investigated the use of environmentally friendly extraction methods to obtain bioactive compounds from Solieria filiformis. The 2:1 PRO:AMG combination showed the highest extraction yields and antiviral activity, suggesting its potential for promoting hydrolytic breakdown of high molecular weight polysaccharides and enhancing bioactivity of the extracts. Further research, including separation and purification techniques, is needed to explore the full potential of these extracts.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2021)

Review Biochemistry & Molecular Biology

Pullulan in biomedical research and development - A review

Ram Sarup Singh et al.

Summary: Pullulan is a microbial exo-polymer produced by yeast like fungus Aureobasidium pullulans, with distinctive physico-chemical properties that make it a potent candidate for biomedical applications.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2021)

Review Biotechnology & Applied Microbiology

Grand Challenges for Industrializing Polyhydroxyalkanoates (PHAs)

Dan Tan et al.

Summary: Traditional microbial platforms for PHA production have high costs, while next-generation industrial biotechnology utilizing Halomonas spp. enables stable continuous processing of low-cost PHAs, which is expected to reduce production costs and improve process economics.

TRENDS IN BIOTECHNOLOGY (2021)

Article Multidisciplinary Sciences

Antiviral activity of lambda-carrageenan against influenza viruses and severe acute respiratory syndrome coronavirus 2

Yejin Jang et al.

Summary: The study demonstrated that lambda-carrageenan from marine red algae exhibited broad spectrum antiviral activity against influenza A and B viruses as well as SARS-CoV-2, without causing toxicity to host cells. It acts by targeting viral attachment to cell surface receptors and preventing virus entry, showing promise as a potential antiviral agent for preventing respiratory virus infections.

SCIENTIFIC REPORTS (2021)

Article Chemistry, Multidisciplinary

Nano-Hydroxyapatite Derived from Biogenic and Bioinspired Calcium Carbonates: Synthesis and In Vitro Bioactivity

Francesca Cestari et al.

Summary: The study investigated the synthesis of bioactive calcium phosphates using different biogenic calcium carbonates and their effects on cell adhesion and proliferation. The phase composition and densification of the sintered materials were found to be influenced by the source of CaCO3 and sintering temperature. Preliminary in vitro tests showed good cell adhesion and proliferation, with variations observed among different materials.

NANOMATERIALS (2021)

Article Chemistry, Multidisciplinary

Cellulose Nanocrystals for Skin Barrier Protection by Preparing a Versatile Foundation Liquid

Jie Tang et al.

Summary: A novel foundation liquid based on hemp/cellulose nanocrystals has been developed to address post-makeup skin cleaning problems, featuring easy-wiping properties that help prevent damage to the skin barrier caused by excessive cleansing. This innovative formula replaces mineral oil and titanium oxide with hemp/CNCs, creating a moisture barrier with excellent biological compatibility and water resistance. The use of discarded industrial hemp stalk to produce hemp/CNCs showcases its potential as a sustainable alternative in cosmetic research.

ACS OMEGA (2021)

Review Biotechnology & Applied Microbiology

Lignin nanoparticles enter the scene: A promising versatile green tool for multiple applications

Willian Daniel Hahn Schneider et al.

Summary: Lignin nanoparticles are considered a green and sustainable way to utilize renewable resources in various applications. Produced from different lignin types using different methods, these nanoparticles exhibit varying characteristics in terms of morphology, size, and stability. Studies have shown their potential in fields such as antioxidants, drug carriers, and more, making them a promising area of research in biotechnology and green chemistry.

BIOTECHNOLOGY ADVANCES (2021)

Review Biochemistry & Molecular Biology

Chitosan: A review of sources and preparation methods

Shijie (Gabriel) Kou et al.

Summary: This article discusses the production methods and different sources of chitosan, focusing on chemical and biological approaches, and suggests lobster cephalothorax as a potential source for industrial scale chitosan preparation.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2021)

Article Engineering, Biomedical

A comparative study on the mechanical and structural design of nacre in gastropod and bivalve molluscs

A. Goswami

Summary: The study examines shells from four mollusc species to learn lessons from nature, focusing on the structure, stress distribution, and properties of organic material. Various experimental techniques and mechanical models are utilized to determine the mechanical properties of the shells, while DSC and TG-DTA data aid in identifying the composition of organic material in the shells.

JOURNAL OF THE MECHANICAL BEHAVIOR OF BIOMEDICAL MATERIALS (2021)

Review Chemistry, Medicinal

Cosmetic, Biomedical and Pharmaceutical Applications of Fish Gelatin/Hydrolysates

Suhair Al-Nimry et al.

Summary: This review comprehensively covers the preparation, characteristics, modifications, and various applications of fish gelatin, emphasizing its potential in biomedical, cosmetic, and pharmaceutical fields. Fish gelatin is considered immunologically safe, environmentally friendly, and possesses unique rheological properties, making it suitable for specific applications and religious dietary restrictions. However, further research is needed to characterize gelatin hydrolysates and expand into cosmetic and drug delivery applications.

MARINE DRUGS (2021)

Article Multidisciplinary Sciences

Iota-carrageenan neutralizes SARS-CoV-2 and inhibits viral replication in vitro

Martina Morokutti-Kurz et al.

Summary: Iota-carrageenan has shown to inhibit cell entry of SARS-CoV-2 virus and replication, with potential antiviral effects demonstrated in vitro. Clinical studies have also indicated that iota-carrageenan can reduce severity and duration of symptoms caused by various respiratory viruses, suggesting it may be an effective prophylaxis or treatment for SARS-CoV-2 infections.

PLOS ONE (2021)

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Calcite seed-assisted microbial induced carbonate precipitation (MICP)

Jennifer Zehner et al.

Summary: MICP is a biological process inducing biomineralization of CaCO3 to form solid materials similar to concrete, with the crystallization surfaces potentially influencing the precipitation process. This study focuses on the influence of calcite seeds on the MICP process, analyzing the precipitation process through changes in pH and optical density signals. The research shows significant differences in pH evolution between samples with and without calcite seeds, with implications for consolidated MICP materials.

PLOS ONE (2021)

Article Chemistry, Physical

Preparation and Characterization of Fish Skin Collagen Material Modified with β-Glucan as Potential Wound Dressing

Marta Michalska-Sionkowska et al.

Summary: The study analyzed the influence of beta-glucan on collagen material, finding that the addition of beta-glucan can increase the roughness of the material's surface, making it more rigid and providing a more hydrophilic character. All materials showed antioxidant activity and did not cause erythrocyte hemolysis.

MATERIALS (2021)

Review Microbiology

Insect Derived Lauric Acid as Promising Alternative Strategy to Antibiotics in the Antimicrobial Resistance Scenario

Luca Borrelli et al.

Summary: This review focuses on the anti-infective effects of insect-derived MCFAs LA and its derivatives, emphasizing the potential of insect lipids in the current global scenario where a sustainable and circular economy is required.

FRONTIERS IN MICROBIOLOGY (2021)

Review Materials Science, Biomaterials

Plant-Based Scaffolds in Tissue Engineering

Asu Ceren Bilirgen et al.

Summary: This study explores the principles, applications, and advantages of plant-based decellularized scaffolds, including the use of cellulose skeleton as a scaffold, advantages over synthetic polymers or animal-derived scaffolds, and adjustable variables to modify scaffold properties.

ACS BIOMATERIALS SCIENCE & ENGINEERING (2021)

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Comparative study on the gel properties and nanostructures of gelatins from chicken, porcine, and tilapia skin

Ying Xin et al.

Summary: The study compared the gel properties and nanostructures of chicken skin gelatin with commercial gelatins from porcine skin and tilapia skin. It found that chicken skin gelatin exhibited superior properties due to its higher imino acid content and ability to form intramolecular hydrogen bonds. Additionally, atomic force microscopy results showed that chicken skin gelatin had larger spherical aggregates, leading to dense rigid gel formation.

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Biomaterials from the sea: Future building blocks for biomedical applications

Mei-chen Wan et al.

Summary: Marine resources hold great potential for developing high-value biomaterials, with materials such as chitin, marine-derived collagen, and more showcasing excellent biocompatibility, biodegradability, and bioactive characteristics. These marine biomaterials find important applications in medical, antimicrobial, drug delivery, rehabilitation, and industrial areas.

BIOACTIVE MATERIALS (2021)

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Hyperspectral interference tomography of nacre

Jad Salman et al.

Summary: This study presents an all-optical, rapid, and nondestructive imaging technique for mapping the structural parameters of nacre and other disordered layered materials. Through this technique, researchers observed a decrease in tablet thickness in red abalone shells at different stages of development.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2021)

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Global declines in coral reef calcium carbonate production under ocean acidification and warming

Christopher E. Cornwall et al.

Summary: Ocean warming and acidification pose a significant threat to the future growth of coral reefs, with projected declines in coral reef net carbonate production rates under different emission scenarios. Bleaching events leading to reduced coral cover are the main drivers of these declines, emphasizing the urgent need for stabilization of atmospheric CO2 emissions to ensure the functional roles of coral reefs are maintained.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2021)

Review Polymer Science

Biomedical Applications of Bacteria-Derived Polymers

Jonathan David Hinchliffe et al.

Summary: Plastics have been widely used in various fields, especially in biomedical applications. Recent focus has shifted to manufacturing polymers using biological methods to reduce environmental costs and reliance on toxic substances. Bacteria-derived polymers offer unique biological properties that meet the demands of the biomaterials industry for highly customized, biocompatible materials.

POLYMERS (2021)

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Combination of Computational Techniques to Obtain High-Quality Gelatin-Base Gels from Chicken Feet

Jose C. C. Santana et al.

Summary: Due to the increasing global population and demand, exploring new food sources with good sensory characteristics is necessary. Continuous innovation through new technologies and tools is essential for developing competitive food products.

POLYMERS (2021)

Review Biochemistry & Molecular Biology

Bioactive potential of natural biomaterials: identification, retention and assessment of biological properties

Kieran Joyce et al.

Summary: Biomaterials play a critical role in biomedical device design and tissue engineering, utilizing natural substrates with inherent bioactive potential. However, residual bioactivity is often overlooked. Research methods include initial material characterization, material processing, and biological evaluation, aimed at optimizing the bioactive potential of substrates to promote tissue regeneration.

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Esfahani Arezoo et al.

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Evaluation of the thermomechanical properties and biodegradation of brown rice starch-based chitosan biodegradable composite films

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Ulvan lyase assisted structural characterization of ulvan from Ulva pertusa and its antiviral activity against vesicular stomatitis virus

Yongzhou Chi et al.

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Ruth Naomi et al.

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Ulvan: A systematic review of extraction, composition and function

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Comparison of different types and sources of chitosan for the treatment of infections in the oral cavity

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Marine Collagen/Apatite Composite Scaffolds Envisaging Hard Tissue Applications

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MARINE DRUGS (2018)

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Extracellular matrix supports healing of transected rabbit Achilles tendon

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HELIYON (2018)

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Nacre, a natural, multi-use, and timely biomaterial for bone graft substitution

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JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A (2017)

Article Agriculture, Multidisciplinary

Nutritional composition of black soldier fly (Hermetia illucens) prepupae reared on different organic waste substrates

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JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE (2017)

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Accelerated wound-healing capabilities of a dressing fabricated from silkworm cocoon

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INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2017)

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Can fungi compete with marine sources for chitosan production?

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Nature's technical ceramic: the avian eggshell

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Heterologous fibrin sealant derived from snake venom: from bench to bedside - an overview

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Bio-functionalization of biomedical metals

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Amorphous calcium carbonate particles form coral skeletons

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PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2017)

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Biological control of aragonite formation in stony corals

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TOXICON (2017)

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Polyhydroxyalkanoates as biomaterials

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Keratin: dissolution, extraction and biomedical application

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Control of nacre biomineralization by Pif80 in pearl oyster

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JetValve: Rapid manufacturing of biohybrid scaffolds for biomimetic heart valve replacement

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Anisotropic tough double network hydrogel from fish collagen and its spontaneous in vivo bonding to bone

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In vitro evaluation of antioxidant and cytotoxic activities of lignin fractions extracted from Acacia nilotica

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Purification, optimization and physicochemical properties of collagen from soft-shelled turtle calipash

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Investigation of three lignin complexes with antioxidant and immunological capacities from Inonotus obliquus

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Does the physiology of chondrichthyan fishes constrain their distribution in the deep sea?

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Biocompatibility evaluation of tissue-engineered decellularized scaffolds for biomedical application

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In vivo erosion of orthopedic screws prepared from nacre (mother of pearl)

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