4.7 Article

Gut microbiota depletion from early adolescence alters anxiety and depression-related behaviours in male mice with Alzheimer-like disease

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Review Clinical Neurology

Emerging role of gut microbiota in modulation of neuroinflammation and neurodegeneration with emphasis on Alzheimer's disease

Divya Goyal et al.

Summary: Recent studies have shown that the gut microbiota interacts with the brain, influencing the pathogenesis of neurodegenerative diseases like Alzheimer's. The bidirectional communication between the gut and the brain suggests that the gut microbiota may play a crucial role in the development of Alzheimer's disease.

PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY (2021)

Article Neurosciences

Antibiotic-induced gut microbiota depletion from early adolescence exacerbates spatial but not recognition memory impairment in adult male C57BL/6 mice with Alzheimer-like disease

Belal Mosaferi et al.

Summary: The study found that antibiotic treatment impaired object recognition memory in healthy mice, while significantly exacerbating spatial memory impairment in mice with Alzheimer-like disease. There were significant correlations between the behavioral tests conducted. Antibiotic treatment also led to a reduction in brain IL-6 levels in healthy animals and decreased cytokines TNF-alpha and IL-6 in Alzheimer's disease-induced mice, showing that gut microbiota manipulation from early adolescence to adulthood may negatively impact cognitive functions.

BRAIN RESEARCH BULLETIN (2021)

Article Developmental Biology

Region-specific sex modulation of central oxytocin receptor by gut microbiota: An ontogenic study

Felix Effah et al.

Summary: This study identified a sex-specific role of gut microbiota on the central oxytocin receptor system in rats, which may have implications in behavioral regulation and the etiology of certain neurodevelopmental disorders.

DEVELOPMENTAL NEUROBIOLOGY (2021)

Article Behavioral Sciences

Environmental enrichment alters neurobehavioral development following maternal immune activation in mice offspring with epilepsy

Maryam Zeraati et al.

Summary: Maternal immune activation can increase seizure susceptibility and psychiatric comorbidities in offspring, leading to anxiety and cognitive deficits with impact on inflammatory parameters, without sex differences in offspring. Environmental enrichment is shown to reverse these effects and can be considered as a potential treatment approach for behavioral abnormalities following maternal immune activation in offspring with epilepsy.

BEHAVIOURAL BRAIN RESEARCH (2021)

Article Psychology, Biological

Treadmill exercise sex-dependently alters susceptibility to depression-like behaviour, cytokines and BDNF in the hippocampus and prefrontal cortex of rats with sporadic Alzheimer-like disease

Saeed Naghibi et al.

Summary: The study demonstrated that treadmill exercise could reduce depression-related behaviors in rats with Alzheimer-like disease, with varying effects in males and females. Exercise decreased body weight, food intake, depression symptoms, and inflammatory cytokines, while increasing anti-inflammatory factors and BDNF levels.

PHYSIOLOGY & BEHAVIOR (2021)

Article Multidisciplinary Sciences

The combination of fluoxetine and environmental enrichment reduces postpartum stress-related behaviors through the oxytocinergic system and HPA axis in mice

Hamideh Bashiri et al.

Summary: Studies suggest that gestational stress may increase the risk of postpartum depression, with drug treatment potentially causing adverse effects on the fetus, while environmental enrichment shows promise in reducing stress. In mouse experiments, a subthreshold dose of FLX in combination with EE reduced the impact of gestational stress on behavior, HPA axis function, and oxytocin levels in dams.

SCIENTIFIC REPORTS (2021)

Editorial Material Neurosciences

The continued need for animals to advance brain research

Judith R. Homberg et al.

Summary: Policymakers are working towards promoting animal-free alternatives in scientific research and have implemented strict regulations for animal research. However, in the field of neuroscience research, it is argued that the use of animals should not be compromised until viable and translational alternatives are available and proven to be valuable.

NEURON (2021)

Article Reproductive Biology

Perinatal fluoxetine dose-dependently affects prenatal stress-induced neurobehavioural abnormalities, HPA-axis functioning and underlying brain alterations in rat dams and their offspring

Mohammad Amani et al.

Summary: Our study found that prenatal stress induced anxiety and depressive behaviors in pregnant and postpartum dams, and in offspring, as well as affecting HPA-axis function. Maternal stress impaired object recognition but did not affect spatial memory in offspring. Prenatal stress decreased whole-brain serotonin and brain-derived neurotrophic factor, and increased interleukin-17 and malondialdehyde, but did not affect oxytocin and interleukin-6 in the brains of offspring.

REPRODUCTIVE TOXICOLOGY (2021)

Review Clinical Neurology

Gut microbiota and major depressive disorder: A systematic review and meta-analysis

Kenji Sanada et al.

JOURNAL OF AFFECTIVE DISORDERS (2020)

Review Neurosciences

The microbiota and the hypothalamus-pituitary-adrenocortical (HPA) axis, implications for anxiety and stress disorders

Linoy Mia Frankiensztajn et al.

CURRENT OPINION IN NEUROBIOLOGY (2020)

Article Immunology

Long-Term Exposure to Ceftriaxone Sodium Induces Alteration of Gut Microbiota Accompanied by Abnormal Behaviors in Mice

Zhongyi Zhao et al.

FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY (2020)

Review Psychiatry

Altered Composition of Gut Microbiota in Depression: A Systematic Review

Zahra Amirkhanzadeh Barandouzi et al.

FRONTIERS IN PSYCHIATRY (2020)

Review Immunology

Gut microbiota in neurodegenerative disorders

Suparna Roy Sarkar et al.

JOURNAL OF NEUROIMMUNOLOGY (2019)

Review Cell Biology

Gut Microbiota in Alzheimer's Disease, Depression, and Type 2 Diabetes Mellitus: The Role of Oxidative Stress

Maria Luca et al.

OXIDATIVE MEDICINE AND CELLULAR LONGEVITY (2019)

Review Clinical Neurology

Gut Microbiota and the Neuroendocrine System

Aitak Farzi et al.

NEUROTHERAPEUTICS (2018)

Review Cell Biology

Oxidative Stress and the Microbiota-Gut-Brain Axis

Laura Dumitrescu et al.

OXIDATIVE MEDICINE AND CELLULAR LONGEVITY (2018)

Article Clinical Neurology

Antidepressant drugs for beta amyloid-induced depression: A new standpoint?

Stefania Schiavone et al.

PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY (2017)

Article Immunology

Microbiota Modulate Anxiety-Like Behavior and Endocrine Abnormalities in Hypothalamic-Pituitary-Adrenal Axis

Ran Huo et al.

FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY (2017)

Article Behavioral Sciences

Absence of gut microbiota influences lipopolysaccharide-induced behavioral changes in mice

Alline C. Campos et al.

BEHAVIOURAL BRAIN RESEARCH (2016)

Article Clinical Neurology

The prevalence of neuropsychiatric symptoms in Alzheimer's disease: Systematic review and meta-analysis

Qing-Fei Zhao et al.

JOURNAL OF AFFECTIVE DISORDERS (2016)

Article Immunology

Gut microbiota depletion from early adolescence in mice: Implications for brain and behaviour

Lieve Desbonnet et al.

BRAIN BEHAVIOR AND IMMUNITY (2015)

Review Biochemical Research Methods

Gut brain axis: diet microbiota interactions and implications for modulation of anxiety and depression

Ruth Ann Luna et al.

CURRENT OPINION IN BIOTECHNOLOGY (2015)

Article Behavioral Sciences

Adolescent silymarin treatment increases anxiety-like behaviors in adult mice

Morteza Kosari-Nasab et al.

BEHAVIOURAL PHARMACOLOGY (2014)

Article Neurosciences

Oxidative Imbalance and Anxiety Disorders

R. Krolow et al.

CURRENT NEUROPHARMACOLOGY (2014)

Article Gastroenterology & Hepatology

Correlation between the human fecal microbiota and depression

A. Naseribafrouei et al.

NEUROGASTROENTEROLOGY AND MOTILITY (2014)

Review Behavioral Sciences

Making room for oxytocin in understanding depression

Robyn J. McQuaid et al.

NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS (2014)

Article Endocrinology & Metabolism

Absence of the gut microbiota enhances anxiety-like behavior and neuroendocrine response to acute stress in rats

Michele Crumeyrolle-Arias et al.

PSYCHONEUROENDOCRINOLOGY (2014)

Review Endocrinology & Metabolism

HPA axis and aging in depression: Systematic review and meta-analysis

Martino Belvederi Murri et al.

PSYCHONEUROENDOCRINOLOGY (2014)

Article Cell Biology

The gut microbiota influences blood-brain barrier permeability in mice

Viorica Braniste et al.

SCIENCE TRANSLATIONAL MEDICINE (2014)

Review Biotechnology & Applied Microbiology

Oxidative Stress, Prooxidants, and Antioxidants: The Interplay

Anu Rahal et al.

BIOMED RESEARCH INTERNATIONAL (2014)

Article Biotechnology & Applied Microbiology

Alterations of the gut microbiota in high-fat diet mice is strongly linked to oxidative stress

Yi Qiao et al.

APPLIED MICROBIOLOGY AND BIOTECHNOLOGY (2013)

Letter Biochemistry & Molecular Biology

Amyloid-β oligomers link depressive-like behavior and cognitive deficits in mice

J. H. Ledo et al.

MOLECULAR PSYCHIATRY (2013)

Article Geriatrics & Gerontology

Deregulation of hypothalamic-pituitary-adrenal axis functions in an Alzheimer's disease rat model

Anthony Brureau et al.

NEUROBIOLOGY OF AGING (2013)

Editorial Material Gastroenterology & Hepatology

Melancholic microbes: a link between gut microbiota and depression?

T. G. Dinan et al.

NEUROGASTROENTEROLOGY AND MOTILITY (2013)

Article Gastroenterology & Hepatology

The Intestinal Microbiota Affect Central Levels of Brain-Derived Neurotropic Factor and Behavior in Mice

Premysl Bercik et al.

GASTROENTEROLOGY (2011)

Article Multidisciplinary Sciences

Normal gut microbiota modulates brain development and behavior

Rochellys Diaz Heijtza et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)

Review Neurosciences

Oxidative stress in Alzheimer disease: A possibility for prevention

David J. Bonda et al.

NEUROPHARMACOLOGY (2010)

Review Neurosciences

Oxidative stress in anxiety and comorbid disorders

Iiris Hovatta et al.

NEUROSCIENCE RESEARCH (2010)

Article Immunology

Evidence that oxidative stress is linked to anxiety-related behaviour in mice

Hassan Rammal et al.

BRAIN BEHAVIOR AND IMMUNITY (2008)

Article Biochemistry & Molecular Biology

Brain oxidative stress in a triple-transgenic mouse model of Alzheimer disease

Rosa Resende et al.

FREE RADICAL BIOLOGY AND MEDICINE (2008)

Review Neurosciences

The HPA axis in major depression: classical theories and new developments

Carmine M. Pariante et al.

TRENDS IN NEUROSCIENCES (2008)