相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。Targeting centrosome amplification, an Achilles' heel of cancer
Dorota Sabat-Pospiech et al.
BIOCHEMICAL SOCIETY TRANSACTIONS (2019)
GTP-tubulin loves microtubule plus ends but marries the minus ends
Linda Wordeman
JOURNAL OF CELL BIOLOGY (2019)
Vinca alkaloids and analogues as anti-cancer agents: Looking back, peering ahead
Emanuela Martino et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2018)
Microtubule dynamics: an interplay of biochemistry and mechanics
Gary J. Brouhard et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2018)
Coming into Focus: Mechanisms of Microtubule Minus-End Organization
Maud Martin et al.
TRENDS IN CELL BIOLOGY (2018)
Microtubules and Microtubule-Associated Proteins
Holly Goodson et al.
COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY (2018)
6α-Acetoxyanopterine: A Novel Structure Class of Mitotic Inhibitor Disrupting Microtubule Dynamics in Prostate Cancer Cells
Claire Levrier et al.
MOLECULAR CANCER THERAPEUTICS (2017)
Cell death response to anti-mitotic drug treatment in cell culture, mouse tumor model and the clinic
Jue Shi et al.
ENDOCRINE-RELATED CANCER (2017)
TOG-tubulin binding specificity promotes microtubule dynamics and mitotic spindle formation
Amy E. Byrnes et al.
JOURNAL OF CELL BIOLOGY (2017)
Precocious centriole disengagement and centrosome fragmentation induced by mitotic delay
Menuka Karki et al.
NATURE COMMUNICATIONS (2017)
Potential anticancer role of colchicine-based derivatives: an overview
Ashok Kumar et al.
ANTI-CANCER DRUGS (2017)
Structures of a diverse set of colchicine binding site inhibitors in complex with tubulin provide a rationale for drug discovery
Yuxi Wang et al.
FEBS JOURNAL (2016)
Mechanisms of Mitotic Spindle Assembly
Sabine Petry
ANNUAL REVIEW OF BIOCHEMISTRY, VOL 85 (2016)
Isolation of Functional Tubulin Dimers and of Tubulin- Associated Proteins from Mammalian Cells
Nuo Yu et al.
CURRENT BIOLOGY (2016)
The Molecular Biology of Spindle Assembly Checkpoint Signaling Dynamics
Andrea Musacchio
CURRENT BIOLOGY (2015)
γ-Tubulin complexes in microtubule nucleation and beyond
Berl R. Oakley et al.
MOLECULAR BIOLOGY OF THE CELL (2015)
Targeting Mitosis in Cancer: Emerging Strategies
Carmen Dominguez-Brauer et al.
MOLECULAR CELL (2015)
Control of microtubule organization and dynamics: two ends in the limelight
Anna Akhmanova et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2015)
One-Pot Tandem Palladium-Catalyzed Decarboxylative Cross-Coupling and CH Activation Route to Thienoisoquinolines
Fei Chen et al.
ADVANCED SYNTHESIS & CATALYSIS (2014)
Microtubule-targeting agents are clinically successful due to both mitotic and interphase impairment of microtubule function
Jessica J. Field et al.
BIOORGANIC & MEDICINAL CHEMISTRY (2014)
Increased microtubule assembly rates influence chromosomal instability in colorectal cancer cells
Norman Ertych et al.
NATURE CELL BIOLOGY (2014)
Cytotoxicity of Paclitaxel in Breast Cancer Is due to Chromosome Missegregation on Multipolar Spindles
Lauren M. Zasadil et al.
SCIENCE TRANSLATIONAL MEDICINE (2014)
Microtubule-Depolymerizing Kinesins
Claire E. Walczak et al.
ANNUAL REVIEW OF CELL AND DEVELOPMENTAL BIOLOGY, VOL 29 (2013)
Aurora B Inhibits MCAK Activity through a Phosphoconformational Switch that Reduces Microtubule Association
Stephanie C. Ems-McClung et al.
CURRENT BIOLOGY (2013)
Coordination of adjacent domains mediates TACC3-ch-TOG-clathrin assembly and mitotic spindle binding
Fiona E. Hood et al.
JOURNAL OF CELL BIOLOGY (2013)
Let's huddle to prevent a muddle: centrosome declustering as an attractive anticancer strategy
A. Ogden et al.
CELL DEATH AND DIFFERENTIATION (2012)
The Tubulin Colchicine Domain: a Molecular Modeling Perspective
Alberto Massarotti et al.
CHEMMEDCHEM (2012)
Clathrin promotes centrosome integrity in early mitosis through stabilization of centrosomal ch-TOG
Amy B. Foraker et al.
JOURNAL OF CELL BIOLOGY (2012)
An Antitubulin Agent BCFMT Inhibits Proliferation of Cancer Cells and Induces Cell Death by Inhibiting Microtubule Dynamics
Ankit Rai et al.
PLOS ONE (2012)
Principles of early drug discovery
J. P. Hughes et al.
BRITISH JOURNAL OF PHARMACOLOGY (2011)
Hallmarks of Cancer: The Next Generation
Douglas Hanahan et al.
CELL (2011)
A critical role of integrin-linked kinase, ch-TOG and TACC3 in centrosome clustering in cancer cells
A. B. Fielding et al.
ONCOGENE (2011)
XMAP215 polymerase activity is built by combining multiple tubulin-binding TOG domains and a basic lattice-binding region
Per O. Widlund et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
Regulation of microtubule dynamics by TOG-domain proteins XMAP215/Dis1 and CLASP
Jawdat Al-Bassam et al.
TRENDS IN CELL BIOLOGY (2011)
Proteins Required for Centrosome Clustering in Cancer Cells
Blanka Leber et al.
SCIENCE TRANSLATIONAL MEDICINE (2010)
Microtubules and resistance to tubulin-binding agents
Maria Kavallaris
NATURE REVIEWS CANCER (2010)
Spheroid-based drug screen: considerations and practical approach
Juergen Friedrich et al.
NATURE PROTOCOLS (2009)
The Ability to Survive Mitosis in the Presence of Microtubule Poisons Differs Significantly Between Human Nontransformed (RPE-1) and Cancer (U2OS, HeLa) Cells
Daniela A. Brito et al.
CELL MOTILITY AND THE CYTOSKELETON (2009)
XMAP215 is a processive microtubule polymerase
Gary J. Brouhard et al.
CELL (2008)
Effects of anti-microtubule agents on microtubule organization in cells lacking the kinesin-13 MCAK
David G. Hedrick et al.
CELL CYCLE (2008)
MCAK-Independent Functions of ch-Tog/XMAP215 in Microtubule Plus-End Dynamics
Alexis R. Barr et al.
MOLECULAR AND CELLULAR BIOLOGY (2008)
How do microtubule-targeted drugs work? An overview
Mary Ann Jordan et al.
CURRENT CANCER DRUG TARGETS (2007)
Structural basis for the regulation of tubulin by vinblastine
B Gigant et al.
NATURE (2005)
Differential functional interplay of TOGp/XMAP215 and the KinI kinesin MCAK during interphase and mitosis
P Holmfeldt et al.
EMBO JOURNAL (2004)
Aurora B regulates MCAK at the mitotic centromere
PD Andrews et al.
DEVELOPMENTAL CELL (2004)
The ch-TOG/XMAP215 protein is essential for spindle pole organization in human somatic cells
F Gergely et al.
GENES & DEVELOPMENT (2003)