4.7 Article

A machine learning pipeline revealing heterogeneous responses to drug perturbations on vascular smooth muscle cell spheroid morphology and formation

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Biochemical Research Methods

A deep learning-based segmentation pipeline for profiling cellular morphodynamics using multiple types of live cell microscopy

Junbong Jang et al.

Summary: MARS-Net is a deep learning network that accurately segments cell edges using data from different types of microscopes. By training on various microscope data, MARS-Net achieves more accurate edge localization compared to neural network models trained on single datasets. It is expected to accelerate studies on cellular morphodynamics by providing accurate pixel-level segmentation of complex live-cell datasets.

CELL REPORTS METHODS (2021)

Article Surgery

RhoA inhibitor-eluting stent attenuates restenosis by inhibiting YAP signaling

Chen Huang et al.

JOURNAL OF VASCULAR SURGERY (2019)

Article Oncology

CDC42 promotes vascular calcification in chronic kidney disease

Zehua Li et al.

JOURNAL OF PATHOLOGY (2019)

Article Biochemical Research Methods

U-Net: deep learning for cell counting, detection, and morphometry

Thorsten Falk et al.

NATURE METHODS (2019)

Article Cardiac & Cardiovascular Systems

Opportunities and Challenges in Cardiovascular Pharmacogenomics From Discovery to Implementation

Dan M. Roden et al.

CIRCULATION RESEARCH (2018)

Article Biochemistry & Molecular Biology

CellProfiler 3.0: Next-generation image processing for biology

Claire McQuin et al.

PLOS BIOLOGY (2018)

Article Multidisciplinary Sciences

Deep transfer learning-based hologram classification for molecular diagnostics

Sung-Jin Kim et al.

SCIENTIFIC REPORTS (2018)

Article Cell Biology

Rac GTPase regulation of 3D invasion in neuroblastomas lacking MYCN amplification

Camilla B. Mitchell et al.

CELL ADHESION & MIGRATION (2017)

Article Multidisciplinary Sciences

Curvature and Rho activation differentially control the alignment of cells and stress fibers

Nathan D. Bade et al.

SCIENCE ADVANCES (2017)

Article Multidisciplinary Sciences

Measuring the Stiffness of Ex Vivo Mouse Aortas Using Atomic Force Microscopy

Yong Ho Bae et al.

JOVE-JOURNAL OF VISUALIZED EXPERIMENTS (2016)

Article Computer Science, Interdisciplinary Applications

AnaSP: A software suite for automatic image analysis of multicellular spheroids

Filippo Piccinini

COMPUTER METHODS AND PROGRAMS IN BIOMEDICINE (2015)

Article Multidisciplinary Sciences

Apolipoprotein E3 Inhibits Rho to Regulate the Mechanosensitive Expression of Cox2

Bernadette Y. Hsu et al.

PLOS ONE (2015)

Review Cell Biology

3D Cell Culture Systems: Advantages and Applications

Maddaly Ravi et al.

JOURNAL OF CELLULAR PHYSIOLOGY (2015)

Review Biochemical Research Methods

Three-Dimensional Cell Culture Systems and Their Applications in Drug Discovery and Cell-Based Biosensors

Rasheena Edmondson et al.

ASSAY AND DRUG DEVELOPMENT TECHNOLOGIES (2014)

Article Cardiac & Cardiovascular Systems

Transdifferentiation of Vascular Smooth Muscle Cells to Macrophage-Like Cells During Atherogenesis

Susanne Feil et al.

CIRCULATION RESEARCH (2014)

Article Cardiac & Cardiovascular Systems

Smooth muscle cells and vascular diseases

J.-B. Michel et al.

CARDIOVASCULAR RESEARCH (2012)

Article Hematology

Focal Adhesion Kinase Regulates Smooth Muscle Cell Recruitment to the Developing Vasculature

Zhaokang Cheng et al.

ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2011)

Article Biochemistry & Molecular Biology

Computer Vision in Cell Biology

Gaudenz Danuser

Article Multidisciplinary Sciences

A Simple Hanging Drop Cell Culture Protocol for Generation of 3D Spheroids

Ramsey Foty

JOVE-JOURNAL OF VISUALIZED EXPERIMENTS (2011)

Review Physics, Multidisciplinary

Community detection in graphs

Santo Fortunato

PHYSICS REPORTS-REVIEW SECTION OF PHYSICS LETTERS (2010)

Article Biochemistry & Molecular Biology

Cell-Cycle Control by Physiological Matrix Elasticity and In Vivo Tissue Stiffening

Eric A. Klein et al.

CURRENT BIOLOGY (2009)

Article Biochemical Research Methods

Spheroid-based drug screen: considerations and practical approach

Juergen Friedrich et al.

NATURE PROTOCOLS (2009)

Article Cardiac & Cardiovascular Systems

Ethnic differences in cardiovascular drug response potential contribution of pharmacogenetics

Julie A. Johnson

CIRCULATION (2008)

Article Biochemistry & Molecular Biology

Specificity and mechanism of action of EHT 1864, a novel small molecule inhibitor of rac family small GTPases

Adam Shutes et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2007)

Review Medicine, General & Internal

Pharmacogenomics: Challenges and opportunities

Dan M. Roden et al.

ANNALS OF INTERNAL MEDICINE (2006)

Article Medicine, General & Internal

Outcomes in hypertensive black and nonblack patients treated with chlorthalidone, amlodipine, and lisinopril

JT Wright et al.

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2005)

Article Hematology

N-cadherin upregulation and function in response of smooth muscle cells to arterial injury

M Jones et al.

ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2002)

Article Medicine, General & Internal

Effect of blood pressure lowering and antihypertensive drug class on progression of hypertensive kidney disease - Results from the AASK trial

JT Wright et al.

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2002)

Article Cell Biology

Timing of cyclin D1 expression within G1 phase is controlled by Rho

CF Welsh et al.

NATURE CELL BIOLOGY (2001)

Article Cardiac & Cardiovascular Systems

A mouse model of vascular injury that induces rapid onset of medial cell apoptosis followed by reproducible neointimal hyperplasia

M Sata et al.

JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY (2000)