Visible light photocatalytic one pot synthesis of Z-arylvinyl halides from E-arylvinyl acids with N-halosuccinimide

An efficient visible light photocatalytic strategy to synthesize thermodynamically less stable Z-arylvinyl halides (with up to >99/1 Z/E ratio and 86% yield) was developed. The reaction combined base-mediated halodecarboxylation of E-arylvinyl acids with N-halosuccinimide and visible light Ir-photocatalyzed isomerization of E-arylvinyl halides in a one pot sequential catalytic process.

Automated summary

An efficient visible light photocatalytic strategy was developed for synthesizing thermodynamically less stable Z-arylvinyl halides. The reaction involved base-mediated halodecarboxylation of E-arylvinyl acids and visible light Ir-photocatalyzed isomerization of E-arylvinyl halides in a one pot sequential catalytic process, resulting in high yields and high Z/E ratios.