☆ 4.6 Article

Supported l-tryptophan on Fe3O4@SiO2 as an efficient and magnetically separable catalyst for one-pot construction of spiro[indene-2,2′-naphthalene]-4′-carbonitrile derivatives

RSC ADVANCES (2022)

相关参考文献

注意：仅列出部分参考文献，下载原文获取全部文献信息。

Review Biochemistry & Molecular Biology

Recent development in the synthesis of heterocycles by 2-naphthol-based multicomponent reactions

Ankita Chaudhary

Summary: 2-Naphthol is a versatile starting material with multiple reactive sites that can be used in various organic transformations to produce biologically active compounds. The use of multicomponent reactions utilizing 2-naphthol has greatly expanded the synthetic utility of this compound for the rapid synthesis of diverse heterocyclic scaffolds with potent biological properties.

MOLECULAR DIVERSITY (2021)

添加到收藏夹

Review Chemistry, Multidisciplinary

Catalytic Enantioselective Isocyanide-Based Reactions: Beyond Passerini and Ugi Multicomponent Reactions

Jian Luo et al.

Summary: This review discusses the recent advancements in catalytic enantioselective isocyanide-based reactions, highlighting the advantages, limitations, possible mechanisms, and synthetic applications of each reaction type. Additionally, it provides a personal outlook on potential opportunities for further exploration in this rapidly growing field.

CHEMISTRY-A EUROPEAN JOURNAL (2021)

添加到收藏夹

Article Chemistry, Multidisciplinary

Convenient construction of spiro[indoline-3,5′-pyrrolo[3,4-c]carbazole] and spiro[indene-2,5′-pyrrolo[3,4-c]carbazole] via acid-catalyzed Diels-Alder reaction

Chen Yan et al.

Summary: The p-TsOH catalyzed Diels-Alder reaction provides a method for the synthesis of various spiro compounds with different structures and properties from 3-(indol-3-yl)maleimides and different substrates.

CHINESE CHEMICAL LETTERS (2021)

添加到收藏夹

Review Chemistry, Applied

Multicomponent and One-pot Syntheses of Quinoxalines

Lukas Biesen et al.

Summary: Quinoxalines are nitrogen-containing bicyclic heterocycles with diverse biological activities and luminescence properties. Their syntheses involve a range of multicomponent methods, such as Ugi-reactions, leading to the development of novel reactions and sequences. Diversity-oriented synthesis and transition metal catalyzed multicomponent reactions offer efficient pathways to quinoxalines and quinoxaline-containing moieties.

ADVANCED SYNTHESIS & CATALYSIS (2021)

添加到收藏夹

Article Biochemistry & Molecular Biology

Synthesis, antidiabetic activity and molecular docking study of rhodanine-substitued spirooxindole pyrrolidine derivatives as novel α-amylase inhibitors

Amani Toumi et al.

Summary: This study synthesized a series of novel rhodanine-fused spim [pyrrolidine-2,3'-oxindoles], showcasing efficient construction of diverse structures and excellent inhibition of alpha-amylase activity.

BIOORGANIC CHEMISTRY (2021)

添加到收藏夹

Review Chemistry, Medicinal

Multicomponent reactions (MCR) in medicinal chemistry: a patent review (2010-2020)

Hafiza Amna Younus et al.

Summary: Multicomponent reactions (MCR) play a crucial role in synthesizing complex-functionalized molecules of high biological significance, allowing for the quick establishment of libraries of bioactive compounds for the discovery of potential therapeutic agents.

EXPERT OPINION ON THERAPEUTIC PATENTS (2021)

添加到收藏夹

Article Multidisciplinary Sciences

Application of novel nanomagnetic metal-organic frameworks as a catalyst for the synthesis of new pyridines and 1,4-dihydropyridines via a cooperative vinylogous anomeric based oxidation

Hassan Sepehrmansourie et al.

Summary: The new magnetic metal-organic frameworks based on Fe3O4 exhibit excellent properties and can be used to prepare compounds with potential as drug candidates. The methodology offers significant advantages such as mild reaction conditions, high efficiency, easy operation, short reaction times, high thermal stability, and reusability of the catalyst.

SCIENTIFIC REPORTS (2021)

添加到收藏夹

Article Chemistry, Applied

Vinylogous Aza-Michael Addition of Urea Derivatives with p-Quinone Methides Followed by Oxidative Dearomative Cyclization: Approach to Spiroimidazolidinone Derivatives

Navpreet Kaur et al.

Summary: An efficient protocol for the synthesis of spiro-imidazolidinone-cyclohexadienones from p-quinone methides and dialkyloxy ureas is reported, showing good functional group tolerance and providing a straightforward method for accessing the desired compounds. Additionally, the debenzylation of spiroimidazolidinones to give N-hydroxycyclic ureas has been demonstrated in follow-up chemistry.

ADVANCED SYNTHESIS & CATALYSIS (2021)

添加到收藏夹

Article Chemistry, Medicinal

Structural insights of oxindole based kinase inhibitors as anticancer agents: Recent advances

Prajwal Dhokne et al.

Summary: Small-molecule kinase inhibitors are being explored as promising anticancer therapeutics due to the deregulation of kinases in cancerous tissues. Oxindole motifs have shown significant inhibitory activity against multiple kinases, making them privileged scaffolds for development. Recent advances in oxindole-based kinase inhibitors, including their structural frameworks, design strategies, and mechanism of action have been summarized in this review.

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2021)

添加到收藏夹

Review Chemistry, Multidisciplinary

Magnetic nanoparticles for cancer theranostics: Advances and prospects

Xuexin Li et al.

Summary: Nanoparticles have emerged as a novel approach in cancer diagnosis and treatment, showing great potential in medical applications. However, more research is needed to improve their toxicity and efficacy for clinical use.

JOURNAL OF CONTROLLED RELEASE (2021)

添加到收藏夹

Article Chemistry, Organic

Multicomponent Reaction for Diastereoselective Synthesis of Spiro[carbazole-3,4 '-pyrazoles] and Spiro[carbazole-3,4 '-thiazoles]

Shao-Cong Zhan et al.

Summary: The presence of copper sulfate enables the three-component and four-component reactions involving aromatic aldehydes, ethylindole-3-acetate, and various small molecules to proceed efficiently in refluxing toluene, yielding spiro[carbazole-3,4'-pyrazoles] and spiro[carbazole-3,4'-thiazoles] with high diastereoselectivity. The reaction outcomes demonstrate the versatility and potential utility of CuSO4 catalysis in diverse multi-component reactions.

JOURNAL OF ORGANIC CHEMISTRY (2021)

添加到收藏夹

Article Chemistry, Organic

Regio- and Stereoselective Synthesis of Dispiro-bisoxindoles via [3+2] Annulation Involving Nitroisatylidene as a Vinylogous Michael Donor

Chenikkayala Siva Sankara et al.

Summary: The cascade [3+2] annulation described involves a gamma-selective vinylogous Michael addition followed by an intramolecular Michael addition, yielding dispiro-bis-oxindoles and spiro-oxindoles with up to four contiguous chiral centers. This transformation provides a convenient entry into conformationally constrained gamma-amino acid derivatives.

ORGANIC LETTERS (2021)

添加到收藏夹

Review Chemistry, Multidisciplinary

Synthesis of iron-based magnetic nanocomposites: A review

Is Fatimah et al.

Summary: The paper presents a review on the development of iron oxide-based magnetic nanocomposites, focusing on the synthesis methods, materials, and various factors influencing their properties. Future perspectives for development are also highlighted in the study.

ARABIAN JOURNAL OF CHEMISTRY (2021)

添加到收藏夹

Article Chemistry, Multidisciplinary

A Bronsted acidic ionic liquid anchored to magnetite nanoparticles as a novel recoverable heterogeneous catalyst for the Biginelli reaction

Hourieh Sadat Oboudatian et al.

Summary: This study utilized a chemical co-precipitation method to prepare Fe3O4 nanoparticles, followed by coating a SiO2 shell using the Stober method, and finally coating CPTES and morpholine on the SiO2 shell to successfully synthesize Mag@Morph-AIL. The nanocatalyst showed easy separation, recyclability, non-toxicity, versatility, high stability, short reaction times, and excellent yields, making it a useful method for the preparation of 3,4-dihydropyrimidinones.

RSC ADVANCES (2021)

添加到收藏夹

Review Chemistry, Multidisciplinary

Arenesulfonyl indole: new precursor for diversification of C-3 functionalized indoles

Banni Preet Kaur et al.

Summary: Arenesulfonyl indoles, with a good leaving group, serve as effective precursors for vinylogous imine intermediates generated in situ under basic conditions. These intermediates readily react with other nucleophilic reagents to yield C-3 substituted indole derivatives. The success of this substrate in organic synthesis is attributed to the stability of arylsulfonyl-containing substrates, mild reaction conditions, and the wide variety of nucleophiles involved.

RSC ADVANCES (2021)

添加到收藏夹

Article Chemistry, Organic

Regioselective synthesis of spiro isoxazole-oxindole-tetrahydrothiophene hybrids via cascade reactions under catalyst-free conditions

Sakkani Nagaraju et al.

JOURNAL OF HETEROCYCLIC CHEMISTRY (2020)

添加到收藏夹

Article Chemistry, Multidisciplinary

Synthesis of 1,2,3-Triazole Tethered 3-Hydroxy-2-oxindoles: Promising Corrosion Inhibitors for Steel in Acidic Medium and Their Anti-Microbial Evaluation

Sugirdha Sampath et al.

CHEMISTRYSELECT (2020)

添加到收藏夹

Review Chemistry, Physical

Preparation, surface functionalization and application of Fe3O4 magnetic nanoparticles

Shixiang Liu et al.

ADVANCES IN COLLOID AND INTERFACE SCIENCE (2020)

添加到收藏夹

Article Chemistry, Organic

Novel one-pot approach to 2-aminofuran derivatives via multicomponent reaction of 3-hydroxy-4H-pyran-4-ones, α-ketoaldehydes and methylene active nitriles

Andrey N. Komogortsev et al.

TETRAHEDRON LETTERS (2020)

添加到收藏夹

Article Chemistry, Multidisciplinary

Synthesis and characterization of new quaternary ammonium surfactant [C18-Dabco][Br] and its catalytic application in the synthesis of spirocarbocycles under ultrasonic condition

Trushant Lohar et al.

RESEARCH ON CHEMICAL INTERMEDIATES (2019)

添加到收藏夹

Article Chemistry, Multidisciplinary

A facile atom economic one pot multicomponent synthesis of bioactive spiro-indenoquinoxaline pyrrolizines as potent antioxidants and anti-cancer agents

Kailasam Saravana Mani et al.

NEW JOURNAL OF CHEMISTRY (2018)

添加到收藏夹

Article Chemistry, Applied

Synthesis of quinazolines over recyclable Fe3O4@SiO2-PrNH2-Fe3+ nanoparticles: A green, efficient, and solvent-free protocol

Esmaiel Eidi et al.

APPLIED ORGANOMETALLIC CHEMISTRY (2018)

添加到收藏夹

Article Chemistry, Applied

Fe3O4@SiO2@l-arginine@Pd(0): a new magnetically retrievable heterogeneous nanocatalyst with high efficiency for C-C bond formation

Arash Ghorbani-Choghamarani et al.

APPLIED ORGANOMETALLIC CHEMISTRY (2016)

添加到收藏夹

Article Chemistry, Organic

Catalyst free ethylene glycol promoted synthesis of spiro[indene-2,2′-naphthalene]-4′-carbonitriles and spiro[naphthalene-2,5′-pyrimidine]-4-carbonitriles via one-pot three-component reaction

Garima Khanna et al.

TETRAHEDRON LETTERS (2016)

添加到收藏夹

Article Chemistry, Multidisciplinary

One-pot multicomponent reaction synthesis of spirooxindoles promoted by guanidine-functionalized magnetic Fe3O4 nanoparticles

Fatemeh Alemi Tameh et al.

RSC ADVANCES (2016)

添加到收藏夹

Review Chemistry, Multidisciplinary

Catalytic C-C Bond-Forming Multi-Component Cascade or Domino Reactions: Pushing the Boundaries of Complexity in Asymmetric Organocatalysis

Chandra M. R. Volla et al.

CHEMICAL REVIEWS (2014)

添加到收藏夹

Article Chemistry, Medicinal

Synthesis of new class of spirocarbocycle derivatives by multicomponent domino reaction and their evaluation for antimicrobial, anticancer activity and molecular docking studies

N. Sudhapriya et al.

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2014)

添加到收藏夹

Article Chemistry, Multidisciplinary

Magnetically retrievable catalysts for organic synthesis

R. B. Nasir Baig et al.

CHEMICAL COMMUNICATIONS (2013)

添加到收藏夹

Article Chemistry, Applied

One-Pot, Three-Component Synthesis of a Library of Spirooxindole-Pyrimidines Catalyzed by Magnetic Nanoparticle Supported Dodecyl Benzenesulfonic Acid in Aqueous Media

Jia Deng et al.

ACS COMBINATORIAL SCIENCE (2012)

添加到收藏夹

Article Engineering, Biomedical

Multi-functional magnetic nanoparticles for magnetic resonance imaging and cancer therapy

Murali M. Yallapu et al.

BIOMATERIALS (2011)

添加到收藏夹

Article Chemistry, Physical

Effect of Various Aminated Single-Walled Carbon Nanotubes on the Epoxy Cross-Linking Reactions

J. M. Gonzalez-Dominguez et al.

JOURNAL OF PHYSICAL CHEMISTRY C (2011)

添加到收藏夹

Article Chemistry, Organic

Direct asymmetric aldol reactions between aldehydes and ketones catalyzed by L-tryptophan in the presence of water

Zhaoqin Jiang et al.

ORGANIC & BIOMOLECULAR CHEMISTRY (2010)

添加到收藏夹

Article Chemistry, Inorganic & Nuclear

Silica-supported L-proline organocatalysts for asymmetric aldolisation

Alexandra Zamboulis et al.

TETRAHEDRON-ASYMMETRY (2009)

添加到收藏夹

Review Pharmacology & Pharmacy

Magnetic nanoparticles in MR imaging and drug delivery

Conroy Sun et al.

ADVANCED DRUG DELIVERY REVIEWS (2008)

添加到收藏夹

Article Chemistry, Applied

Novel prolinamide-supported polystyrene as highly stereoselective and recyclable organocatalyst for the aldol reaction

Michelangelo Gruttadauria et al.

ADVANCED SYNTHESIS & CATALYSIS (2008)

添加到收藏夹

Article Chemistry, Multidisciplinary

Functionalized chiral ionic liquids as highly efficient asymmetric organocatalysts for Michael addition to nitroolefins

Sanzhong Luo et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2006)

添加到收藏夹

© Peeref 2019-2024. All rights reserved.