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The Role of Vitamin Deficiency in Liver Disease: To Supplement or Not Supplement?

期刊

NUTRIENTS
卷 13, 期 11, 页码 -

出版社

MDPI
DOI: 10.3390/nu13114014

关键词

vitamins; chronic liver disease; micronutrients; vitamin supplementation

资金

  1. PO FESR Sicilia 2014-2020, - Alimenti Nutraceutica e SaluteProject TRIAL [08TP1041100162, CUP G48I18001120007, IRIS/U GOV 16463]

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In recent years, there has been a growing interest in the impact of dietary requirements and nutritional factors on chronic diseases, leading to strengthened nutritional programs in public health policies. Abnormalities in vitamin levels are often detected in chronic liver disease, with treatment programs focusing on correcting these deficiencies which are associated with higher rates of comorbidities. Specific knowledge about the role of vitamins in liver disease is emerging, with potential benefits seen from improved vitamin intake combined with pharmacological treatments, particularly in cases of liver tumors. Further studies are still needed in this area.
Over the past few years, growing interest has been shown for the impact of dietary requirements and nutritional factors on chronic diseases. As a result, nutritional programs have been reinforced by public health policies. The precise role of micronutrients in chronic liver disease is currently receiving particular attention since abnormalities in vitamin levels are often detected. At present, treatment programs are focused on correcting vitamin deficiencies, which are frequently correlated to higher rates of comorbidities with poor outcomes. The literature reviewed here indicates that liver diseases are often related to vitamin disorders, due to both liver impairment and abnormal intake. More specific knowledge about the role of vitamins in liver disease is currently emerging from various results and recent evidence. The most significant benefits in this area may be observed when improved vitamin intake is combined with a pharmacological treatment that may also affect the progression of the liver disease, especially in the case of liver tumors. However, further studies are needed.

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