期刊
NUTRIENTS
卷 13, 期 11, 页码 -出版社
MDPI
DOI: 10.3390/nu13114001
关键词
asthma; micronutrients; immunity; oxidative stress; inflammation; supplementation
Asthma, a chronic inflammatory disease, is influenced not only by traditional risk factors but also by disturbances in micronutrient levels. The impact of micronutrients on the prevalence and severity of asthma is discussed in this review.
Asthma represents one of the most common medical issues in the modern world. It is a chronic inflammatory disease characterized by persistent inflammation of the airways and disturbances in redox status, leading to hyperresponsiveness of bronchi and airway obstruction. Apart from classical risk factors such as air pollution, family history, allergies, or obesity, disturbances of the levels of micronutrients lead to impairments in the defense mechanisms of the affected organism against oxidative stress and proinflammatory stimuli. In the present review, the impact of micronutrients on the prevalence, severity, and possible risk factors of asthma is discussed. Although the influence of classical micronutrients such as selenium, copper, or zinc are well known, the effects of those such as iodine or manganese are only rarely mentioned. As a consequence, the aim of this paper is to demonstrate how disturbances in the levels of micronutrients and their supplementation might affect the course of asthma.
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