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Advances in Sintering Techniques for Calcium Phosphates Ceramics

期刊

MATERIALS
卷 14, 期 20, 页码 -

出版社

MDPI
DOI: 10.3390/ma14206133

关键词

calcium phosphates; sintering; bioceramics; bone tissue engineering

资金

  1. European Unions Horizon 2020 research and innovation program [857287]
  2. European Regional Development Fund [1.1.1.2/VIAA/2/18/318]

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Calcium phosphate (CaP) biomaterials are widely used for bone defect reconstruction, but traditional sintering may lead to the formation of secondary phases and excessive grain growth. Therefore, researchers are exploring advanced sintering techniques to improve the densification of CaPs.
Calcium phosphate (CaP) biomaterials are extensively used to reconstruct bone defects. They resemble a chemical similarity to the inorganic mineral present in bones. Thus, they are termed as the key players in bone regeneration. Sintering is a heat treatment process applied to CaP powder compact or fabricated porous material to impart strength and integrity. Conventional sintering is the simplest sintering technique, but the processing of CaPs at a high temperature for a long time usually leads to the formation of secondary phases due to their thermal instability. Furthermore, it results in excessive grain growth that obstructs the densification process, limiting the application of CaP's ceramics in bone regeneration. This review focuses on advanced sintering techniques used for the densification of CaPs. These techniques utilize the synergy of temperature with one or more parameters such as external pressure, electromagnetic radiation, electric current, or the incorporation of transient liquid that boosts the mass transfer while lowering the sintering temperature and time.

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