期刊
MATERIALS
卷 14, 期 21, 页码 -出版社
MDPI
DOI: 10.3390/ma14216281
关键词
ZnO nanoparticles; borosiloxane; antibacterial agents; composite materials
类别
资金
- Ministry of Science and Higher Education of the Russian Federation [075-15-2020-775]
The study analyzed the antibacterial properties of a composite material based on borosiloxane and zinc oxide nanoparticles (ZnO NPs), showing significant inhibition of E. coli division. Additionally, the composite material did not inhibit the growth and division of mammalian cells. It was demonstrated that incorporating ZnO NPs into borosiloxane could have a positive effect reaching 100% or higher when the viscoelastic properties are retained.
The present study a comprehensive analysis of the antibacterial properties of a composite material based on borosiloxane and zinc oxide nanoparticles (ZnO NPs). The effect of the polymer matrix and ZnO NPs on the generation of reactive oxygen species, hydroxyl radicals, and long-lived oxidized forms of biomolecules has been studied. All variants of the composites significantly inhibited the division of E. coli bacteria and caused them to detach from the substrate. It was revealed that the surfaces of a composite material based on borosiloxane and ZnO NPs do not inhibit the growth and division of mammalians cells. It is shown in the work that the positive effect of the incorporation of ZnO NPs into borosiloxane can reach 100% or more, provided that the viscoelastic properties of borosiloxane with nanoparticles are retained.
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