期刊
MATERIALS
卷 14, 期 19, 页码 -出版社
MDPI
DOI: 10.3390/ma14195643
关键词
photoacoustic; carbon materials; molecular imaging; contrast agents; theragnosis
类别
资金
- National Research Foundation of Korea (NRF) - Korean government (MSIT, Ministry of Science and ICT) [2019R1F1A1055458, 2019R1F1A1062948]
- Bio and Medical Technology Development Program of the NRF - Korean government (MSIT) [NRF-2019M3E5D1A02067958]
- National Research Foundation of Korea [2019M3E5D1A02067958, 2019R1F1A1062948] Funding Source: Korea Institute of Science & Technology Information (KISTI), National Science & Technology Information Service (NTIS)
This review discusses the current state of PAI modality, recent progress on PAI imaging with carbon-based agents, and provides a future perspective on advanced PAI systems using carbon-based agents.
For biomedical imaging, the interest in noninvasive imaging methods is ever increasing. Among many modalities, photoacoustic imaging (PAI), which is a combination of optical and ultrasound imaging techniques, has received attention because of its unique advantages such as high spatial resolution, deep penetration, and safety. Incorporation of exogenous imaging agents further amplifies the effective value of PAI, since they can deliver other specified functions in addition to imaging. For these agents, carbon-based materials can show a large specific surface area and interesting optoelectronic properties, which increase their effectiveness and have proved their potential in providing a theragnostic platform (diagnosis + therapy) that is essential for clinical use. In this review, we introduce the current state of the PAI modality, address recent progress on PAI imaging that takes advantage of carbon-based agents, and offer a future perspective on advanced PAI systems using carbon-based agents.
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